ChemicalBook > CAS DataBase List > 5-Fluoroindole

5-Fluoroindole

Product Name
5-Fluoroindole
CAS No.
399-52-0
Chemical Name
5-Fluoroindole
Synonyms
5-FLUORO-1H-INDOLE;NSC 88613;AKOS JY2082903;5-FLUOROINDOLE;BUTTPARK 24\07-33;Indole, 5-fluoro-;5-Fluoroindole98%;5-Fluoroindole>5-Fluoroindole 98%;5-Fluoroindole,99%
CBNumber
CB7445446
Molecular Formula
C8H6FN
Formula Weight
135.14
MOL File
399-52-0.mol
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5-Fluoroindole Property

Melting point:
45-48 °C (lit.)
Boiling point:
120 °C / 1mmHg
Density 
1.1203 (estimate)
Flash point:
>230 °F
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Crystalline Powder
pka
16.16±0.30(Predicted)
color 
Off-white
BRN 
112350
CAS DataBase Reference
399-52-0(CAS DataBase Reference)
NIST Chemistry Reference
1H-indole, 5-fluoro-(399-52-0)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
F 
10
HazardClass 
IRRITANT
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
F9108
Product name
5-Fluoroindole
Purity
98%
Packaging
1g
Price
$60.9
Updated
2024/03/01
TCI Chemical
Product number
F0369
Product name
5-Fluoroindole
Purity
>98.0%(GC)
Packaging
1g
Price
$34
Updated
2024/03/01
TCI Chemical
Product number
F0369
Product name
5-Fluoroindole
Purity
>98.0%(GC)
Packaging
5g
Price
$109
Updated
2024/03/01
Alfa Aesar
Product number
A15346
Product name
5-Fluoroindole, 99%
Packaging
1g
Price
$50.65
Updated
2024/03/01
Alfa Aesar
Product number
A15346
Product name
5-Fluoroindole, 99%
Packaging
5g
Price
$194.65
Updated
2024/03/01
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5-Fluoroindole Chemical Properties,Usage,Production

Chemical Properties

off-white crystalline powder

Uses

• ;Reactant for preparation of 5-HT6 receptor ligands1• ;Reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators2• ;Reactant for preparation of antitumor agents3• ;Reactant for preparation of antibacterial agents4• ;Reactant for preparation of immunosuppressive agents5• ;Reactant for preparation of Sodium-Dependent Glucose Co-transporter 2 (SGLT2) Inhibitors for the Management of Hyperglycemia in Diabetes6• ;Reactant for preparation of Myeloperoxidase Inhibitors7• ;Reactant fo

Uses

5-Fluoroindole is a reactant used in various syntheses. It was used in the synthesis of Spirotetrahydro β-Carbolines (Spiroindolones), which is a new class of potent and orally efficacious compounds for the treatment of malaria. 5-Fluoroindole was also a reactant in direct indole and pyrrole couplings to carbonyl compound in total synthesis of Acremoauxin A and Oxazinin 3.

Uses

  • Reactant for preparation of 5-HT6 receptor ligands
  • Reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators
  • Reactant for preparation of antitumor agents
  • Reactant for preparation of antibacterial agents
  • Reactant for preparation of immunosuppressive agents
  • Reactant for preparation of Sodium-Dependent Glucose Co-transporter 2 (SGLT2) Inhibitors for the Management of Hyperglycemia in Diabetes
  • Reactant for preparation of Myeloperoxidase Inhibitors
  • Reactant for preparation of Potent Selective Serotonin Reuptake Inhibitors

Definition

ChEBI: An organofluorine compound that is the 5-fluoro derivative of indole.

5-Fluoroindole Preparation Products And Raw materials

Raw materials

ZINC Sodium dithionite 5-Fluoro-2-nitrotoluene Hydrazinium hydroxide solution Ethanol Acetic anhydride N,N-Dimethylformamide Toluene Nickel Sodium bisulfite Sodium nitrite Fluoroboric acid Nitric acid Acetic acid Methanol Sodium hydroxide N,N-Dimethylformamide dimethyl acetal Indole Pyrrolidine

Preparation Products

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5-Fluoroindole Suppliers

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View Lastest Price from 5-Fluoroindole manufacturers

Honest Joy Holdings Limited
Product
5-Fluoroindole 399-52-0
Price
US $0.00/KG
Min. Order
1KG
Purity
97.1%
Supply Ability
100 tons
Release date
2022-02-21
Chemwill Asia Co.,Ltd.
Product
5-Fluoroindole in stock Factory 399-52-0
Price
US $1.00/KG
Min. Order
1KG
Purity
TOP 3 Factory in China
Supply Ability
Top 3 largest production capacity Factory
Release date
2019-04-03
Shaanxi Dideu Medichem Co. Ltd
Product
5-Fluoroindole 399-52-0
Price
US $0.00-0.00/KG
Min. Order
10g
Purity
99.0%+
Supply Ability
100 tons
Release date
2019-12-25

399-52-0, 5-FluoroindoleRelated Search:

Indole-3-butyric acid Indole Indoline Indometacin Indole-3-acetic acid 5-FLUORO-DL-TRYPTOPHAN 2-ETHYLFORMATE-5-FLUOROINDOLE,ETHYL 5-FLUOROINDOLE-2-CARBOXYLATE,Ethyl 5-fluoroindole 5-FLUOROINDOLE-3-ACETIC ACID 6-Chloro-5-fluoroindole 5-FLUOROINDOLE-3-CARBOXALDEHYDE Fluorine 5-Fluorotryptamine hydrochloride 5-Fluoroindole-2-carboxylicacid,99%,5-Fluoroindole-2-carboxylic acid 99% 4,5-DIFLUORO-2-METHYLINDOLE ETHYL 6-FLUOROINDOLE-2-CARBOXYLATE,6-FLUOROINDOLE-2-CARBOXYLIC ACID ETHYL ESTER 5,7-Difluoroindole 6-FLUOROINDOLE-3-ALDEHYDE,6-FLUOROINDOLE-3-CARBALDEHYDE,6-FLUOROINDOLE-3-CARBOXALDEHYDE,6-FLUOROINDOLE-3-CARBOXALDEHYDE 98% (HPLC) 5-Fluoroindole-2-One

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