ML-109

Product Name: ML-109
CAS No.: 1186649-91-1
Chemical Name: ML-109
Synonyms: ML-109;ML-109, 10 mM in DMSO;ML-109 (CID-25246343);N-(4-((5-(3-Benzyl-5-hydroxy-4-oxo-1,2,3,4-tetrahydroquinazolin-2-yl)-2-methoxybenzyl)oxy)phenyl)acetamide;TSH Receptor,Thyrotropin receptor,inhibit,ML-109,ML 109,Inhibitor,Thyroid-stimulating hormone Receptor,ML109;N-(4-{[5-(3-benzyl-5-hydroxy-4-oxo-1,2,3,4-tetrahydroquinazolin-2-yl)-2-methoxyphenyl]methoxy}phenyl)acetamide;N-[4-[[2-Methoxy-5-[1,2,3,4-tetrahydro-5-hydroxy-4-oxo-3-(phenylmethyl)-2-quinazolinyl]phenyl]methoxy]phenyl]acetamide;Acetamide, N-[4-[[2-methoxy-5-[1,2,3,4-tetrahydro-5-hydroxy-4-oxo-3-(phenylmethyl)-2-quinazolinyl]phenyl]methoxy]phenyl]-
CBNumber: CB74796672
Molecular Formula: C31H29N3O5
Formula Weight: 523.58
MOL File: 1186649-91-1.mol

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ML-109 Property

Boiling point:: 810.1±65.0 °C(Predicted)
Density: 1.300±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO:83.0(Max Conc. mg/mL);158.5(Max Conc. mM)
form: Solid
pka: 8.66±0.40(Predicted)
color: White to light yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0069880
Product name: ML-109
Purity: 99.12%
Packaging: 5mg
Price: $350
Updated: 2021/12/16

ChemScene

Product number: CS-0069880
Product name: ML-109
Purity: 99.12%
Packaging: 10mg
Price: $550
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb572982
Product name: ML-109
Purity: >98%
Packaging: 100mg
Price: $1431.4
Updated: 2021/12/16

ChemScene

Product number: CS-0069880
Product name: ML-109
Purity: 99.12%
Packaging: 50mg
Price: $1650
Updated: 2021/12/16

ChemScene

Product number: CS-0069880
Product name: ML-109
Purity: 99.12%
Packaging: 100mg
Price: $2250
Updated: 2021/12/16

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ML-109 Chemical Properties,Usage,Production

Uses

ML-109 is a potent and full thyroid stimulating hormone receptor (TSHR) agonist, with an EC50 of 40 nM.

Definition

ChEBI: N-[4-[[5-[5-hydroxy-4-oxo-3-(phenylmethyl)-1,2-dihydroquinazolin-2-yl]-2-methoxyphenyl]methoxy]phenyl]acetamide is a member of quinazolines.

References

[1] Neumann S, et al. Small-molecule agonists for the thyrotropin receptor stimulate thyroid function in human thyrocytes and mice. Proc Natl Acad Sci U S A. 2009 Jul 28;106(30):12471-6. DOI:10.1073/pnas.0904506106

ML-109 Preparation Products And Raw materials

Raw materials

Preparation Products

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ML-109 Suppliers

China 39 United States 4 Global 43

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4769
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Shanghaizehan biopharma technology co., Ltd.

Tel: 021-61350663 13052117465
Fax: 021-61350662
Email: sales@zehanbiopharma.com
Country: China
ProdList: 984
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

ShangHai Biochempartner Co.,Ltd

Tel: 177-54423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8000
Advantage: 62

Shanghai Rechem science Co., Ltd.

Tel: 021-31433387 15618786686
Fax: QQ:1369748377
Email: sales@rechemscience.com
Country: China
ProdList: 2991
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Shanghai Chaolan Chemical Technology Center

Tel: 021-QQ：65489617 15618227136
Fax: 21-5161 9052
Email: Sales@ATKchemical.com
Country: China
ProdList: 9125
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 18101056239
Email: 3193328036@qq.com
Country: China
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Chuzhou KeMail Chemical Technology Co., Ltd

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Fax: 0550-5196001
Email: wj520wjxby@126.com
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Heze Development Zone chuangli Chemical Co., Ltd.

Tel: 0530-+86-530-529 6766，+86-15666160102 15666160102
Fax: 0530-529 6766
Email: info@chuangli-chem.com
Country: China
ProdList: 836
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Fan De(Beijing) Biotechnology Co., Ltd.

Tel: 15911056312
Email: liming@bio-fount.com
Country: China
ProdList: 9729
Advantage: 58

1186649-91-1, ML-109Related Search:

5-[(4-Nitrobenzoyl)oxy]-2-[(2-pyrimidinylthio)methyl]-4H-pyran-4-one ML-228 ML188 (Racemate) ML 18 ML-098 ML277 ML 204 ML329 ML364 VU0456810 ML188 ML418 [4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone ML213 N-(3,4-difluorophenyl)-2-pyridin-4-ylquinazolin-4-amine ML-327 PTP1B-IN-2 ML264

ML-109

Acetamide, N-[4-[[2-methoxy-5-[1,2,3,4-tetrahydro-5-hydroxy-4-oxo-3-(phenylmethyl)-2-quinazolinyl]phenyl]methoxy]phenyl]-

N-[4-[[2-Methoxy-5-[1,2,3,4-tetrahydro-5-hydroxy-4-oxo-3-(phenylmethyl)-2-quinazolinyl]phenyl]methoxy]phenyl]acetamide

ML-109 (CID-25246343)

TSH Receptor,Thyrotropin receptor,inhibit,ML-109,ML 109,Inhibitor,Thyroid-stimulating hormone Receptor,ML109

N-(4-((5-(3-Benzyl-5-hydroxy-4-oxo-1,2,3,4-tetrahydroquinazolin-2-yl)-2-methoxybenzyl)oxy)phenyl)acetamide

N-(4-{[5-(3-benzyl-5-hydroxy-4-oxo-1,2,3,4-tetrahydroquinazolin-2-yl)-2-methoxyphenyl]methoxy}phenyl)acetamide

ML-109, 10 mM in DMSO

1186649-91-1

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