AC-VDVAD-CHO

Product Name: AC-VDVAD-CHO
CAS No.: 194022-51-0
Chemical Name: AC-VDVAD-CHO
Synonyms: AC-VAVAD-CHO;AC-VDVAD-CHO;AC-VDVAD-ALDEHYDE;CASPASE 2 INHIBITOR;AC-VAL-ASP-VAL-ASP-CHO;AC-VAL-ASP-ALA-ASP-CHO;CASPASE INHIBITOR VIII;AC-VAL-ASP-VAL-ALA-ASP-CHO;CASPASE-2 INHIBITOR (ALDEHYDE);AC-VAL-ASP-VAL-ALA-ASP-ALDEHYDE
CBNumber: CB7488030
Molecular Formula: C23H37N5O10
Formula Weight: 543.57
MOL File: 194022-51-0.mol

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AC-VDVAD-CHO Property

Boiling point:: 996.6±65.0 °C(Predicted)
Density: 1.272±0.06 g/cm3(Predicted)
storage temp.: −20°C
form: solid
pka: 4.19±0.10(Predicted)
Sequence: Ac-Val-Asp-Val-Ala-Asp-CHO

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth

Product number: FA111092
Product name: Ac-Val-Asp-Val-Ala-Asp-aldehyde (pseudo acid)
Packaging: 1mg
Price: $94
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA111092
Product name: Ac-Val-Asp-Val-Ala-Asp-aldehyde (pseudo acid)
Packaging: 2mg
Price: $164
Updated: 2021/12/16

AK Scientific

Product number: 3611CR
Product name: Ac-VDVAD-CHO
Packaging: 2mg
Price: $271
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA111092
Product name: Ac-Val-Asp-Val-Ala-Asp-aldehyde (pseudo acid)
Packaging: 5mg
Price: $328
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA111092
Product name: Ac-Val-Asp-Val-Ala-Asp-aldehyde (pseudo acid)
Packaging: 10mg
Price: $570
Updated: 2021/12/16

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AC-VDVAD-CHO Chemical Properties,Usage,Production

Uses

Ac-VDVAD-CHO is a caspase-2/3 inhibitor (IC50: 46 and 15 nM)[1].

IC 50

Caspase-2: 46 nM (IC₅₀); Caspase-3: 15 nM (IC₅₀)

References

[1] Maillard MC, et al. Exploiting differences in caspase-2 and -3 S? subsites for selectivity: structure-based design, solid-phase synthesis and in vitro activity of novel substrate-based caspase-2 inhibitors. Bioorg Med Chem. 2011 Oct 1;19(19):5833-51. DOI:10.1016/j.bmc.2011.08.020

AC-VDVAD-CHO Preparation Products And Raw materials

Raw materials

Preparation Products

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AC-VDVAD-CHO Suppliers

China 44 Japan 1 Switzerland 2 United Kingdom 4 United States 14 Global 65

3B Pharmachem (Wuhan) International Co.,Ltd.

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Shanghai Hanhong Scientific Co.,Ltd.

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Chemsky (shanghai) International Co.,Ltd

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Country: China
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BOC Sciences

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Country: United States
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Hangzhou Peptidego Biotech Co.,Ltd.

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Shanghai Kanglang Biotechnology Co., Ltd.

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Nanchang Tianzhen Biotechnology Co., Ltd

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Nanjing TGpeptide Biotechnology Co.,Ltd.

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Hangzhou Go Top Peptide Biotech

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DONBOO AMINO ACID COMPANY

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194022-51-0, AC-VDVAD-CHORelated Search:

Z-VAD-FMK AC-IETD-CHO Z-PHE-DL-ALA-FLUOROMETHYLKETONE AC-YVAD-PNA CASPASE INHIBITOR3 AC-VEID-AMC Z-ASP-2,6-DICHLOROBENZOYLOXYMETHYLKETONE Z-YVAD-AFC ALPHA-(TRICHLOROMETHYL)-4-PYRIDINEETHANOL AC-DEVD-AFC PAC1 AC-DEVD-CHO AC-LEHD-AFC AC-LEU-GLU-THR-ASP-AFC AC-VDVAD-PNA MCA-VDVADGWK(DNP)-NH2 AC-VDVAD-AFC AC-VDVAD-AMC

CASPASE 2 INHIBITOR

CASPASE-2 INHIBITOR (ALDEHYDE)

CASPASE INHIBITOR VIII

Acetyl-valyl-aspartyl-valyl-alanyl-aspartal

ACETYL-L-VALYL-L-ASPARTYL-L-VALYL-L-ALANYL-L-ASPART-1-AL

AC-VAVAD-CHO

AC-VDVAD-ALDEHYDE

AC-VDVAD-CHO

AC-VAL-ASP-ALA-ASP-CHO

AC-VAL-ASP-VAL-ASP-CHO

AC-VAL-ASP-VAL-ALA-ASP-ALDEHYDE

AC-VAL-ASP-VAL-ALA-ASP-ALDEHYDE (PSEUDO ACID)

AC-VAL-ASP-VAL-ALA-ASP-CHO

AC-VAL-ASP-VAL-ALA-ASP-H (ALDEHYDE)

N-ACETYL-VAL-ASP-VAL-ALA-ASP-CHO

L-Alaninamide, N-acetyl-L-valyl-L-α-aspartyl-L-valyl-N-[(1S)-2-carboxy-1-formylethyl]-

(3S)-3-[[(2S)-2-acetamido-3-methylbutanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-carboxy-3-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid

194022-51-0

C23H37N5O10

C22H33N5O11

Inhibitors

Caspase 2

Caspases

Cell Biology

Cell Signaling and Neuroscience

Apoptosis and Cell Cycle

BioChemical

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