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ETHYL 5-ISOPROPYLPYRAZOLE-3-CARBOXYLATE

Product Name
ETHYL 5-ISOPROPYLPYRAZOLE-3-CARBOXYLATE
CAS No.
78208-72-7
Chemical Name
ETHYL 5-ISOPROPYLPYRAZOLE-3-CARBOXYLATE
Synonyms
ETHYL 5-ISOPROPYLPYRAZOLE-3-CARBOXYLATE;ETHYL-3-ISOPROPYL PYRAZOLE-5-CARBOXYLATE;ETHYL 5-ISOPROPYLPYRAZOLE-3-CARBOXYLATE, 97;ethyl 3-(propan-2-yl)-1H-pyrazole-5-carboxylate;Ethyl 5-(1-methylethyl)-1H-pyrazole-3-carboxylate;3-ISOPROPYL-1H-PYRAZOLE-5-CARBOXYLICACIDETHYLESTER;5-Isopropyl-1H-pyrazole-3-carboxylic acid ethyl ester;1H-Pyrazole-3-carboxylic acid, 5-(1-Methylethyl)-, ethyl ester
CBNumber
CB7500776
Molecular Formula
C9H14N2O2
Formula Weight
182.22
MOL File
78208-72-7.mol
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ETHYL 5-ISOPROPYLPYRAZOLE-3-CARBOXYLATE Property

Melting point:
75°C
Boiling point:
313.0±30.0 °C(Predicted)
Density 
1.101
storage temp. 
2-8°C
pka
11.36±0.10(Predicted)
Appearance
Light yellow to yellow Solid
InChI
InChI=1S/C9H14N2O2/c1-4-13-9(12)8-5-7(6(2)3)10-11-8/h5-6H,4H2,1-3H3,(H,10,11)
InChIKey
ILTUMWMASHHTOQ-UHFFFAOYSA-N
SMILES
N1C(C(C)C)=CC(C(OCC)=O)=N1
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Safety

HS Code 
2933199090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
E921968
Product name
Ethyl3-isopropyl-1H-pyrazole-5-carboxylate,
Packaging
100mg
Price
$45
Updated
2021/12/16
TRC
Product number
E921968
Product name
Ethyl3-isopropyl-1H-pyrazole-5-carboxylate,
Packaging
250mg
Price
$55
Updated
2021/12/16
TRC
Product number
E921968
Product name
Ethyl3-isopropyl-1H-pyrazole-5-carboxylate,
Packaging
500mg
Price
$65
Updated
2021/12/16
AK Scientific
Product number
Y5548
Product name
Ethyl3-isopropyl-1H-pyrazole-5-carboxylate
Packaging
1g
Price
$77
Updated
2021/12/16
Apolloscientific
Product number
OR909670
Product name
Ethyl3-isopropyl-1H-pyrazole-5-carboxylate,
Purity
98%
Packaging
1g
Price
$100
Updated
2021/12/16
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ETHYL 5-ISOPROPYLPYRAZOLE-3-CARBOXYLATE Chemical Properties,Usage,Production

Uses

Ethyl 3-isopropyl-1H-pyrazole-5-carboxylate,

Synthesis

64195-85-3

78208-72-7

General procedure for the synthesis of ethyl 5-isopropylpyrazole-3-carboxylate from ethyl 2,4-dioxo-5-methyl-hexanoate: a mixture of ethyl 2,4-dioxo-5-methyl-hexanoate (1 g, 5.37 mmol) and hydrazine hydrate (10.7 mmol, 9.64 mol/L) in ethanol (20 mL) was stirred for 1 hr at 75 °C under nitrogen atmosphere. After completion of the reaction, the mixture was concentrated under vacuum. The residue was purified by silica gel column chromatography using petroleum ether: ethyl acetate (2:1, v/v) as eluent to afford ethyl 5-isopropylpyrazole-3-carboxylate (0.55 g, 56% yield) as a light yellow solid. Mass spectrum (ESI, positive ion mode) m/z: 183.1 [M + H]+. 1H NMR (600 MHz, CDCl3) δ: 11.37 (br s, 1H), 6.63 (s, 1H), 4.40-4.37 (m, 2H), 3.07-3.05 (m, 1H), 1.43-1.40 (m, 3H), 1.39- 1.30 (m, 6H).

References

[1] Patent: WO2016/127859, 2016, A1. Location in patent: Paragraph 00202
[2] Patent: WO2015/165835, 2015, A1. Location in patent: Page/Page column 63; 64
[3] Bioorganic and Medicinal Chemistry Letters, 2007, vol. 17, # 20, p. 5620 - 5623
[4] Bioorganic and Medicinal Chemistry Letters, 2009, vol. 19, # 9, p. 2537 - 2541
[5] Patent: US2004/220186, 2004, A1. Location in patent: Page 18

ETHYL 5-ISOPROPYLPYRAZOLE-3-CARBOXYLATE Preparation Products And Raw materials

Raw materials

Preparation Products

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ETHYL 5-ISOPROPYLPYRAZOLE-3-CARBOXYLATE Suppliers

China 92 India 4 Ukraine 1 United States 10 Global 107
Spectrum Info Ltd.
Tel
--
Fax
--
Email
spec-info@spec-info.com
Country
Ukraine
ProdList
512
Advantage
60
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View Lastest Price from ETHYL 5-ISOPROPYLPYRAZOLE-3-CARBOXYLATE manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
Ethyl5-isopropylpyrazole-3-carboxylate 78208-72-7
Price
US $1.60-9.60/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-06-20
Career Henan Chemical Co
Product
ETHYL 5-ISOPROPYLPYRAZOLE-3-CARBOXYLATE, 97 78208-72-7
Price
US $1.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
100KG
Release date
2018-12-22

78208-72-7, ETHYL 5-ISOPROPYLPYRAZOLE-3-CARBOXYLATERelated Search:

Ethyl 3-n-propylpyrazole-5-carboxylate SILDENAFIL-D8 4-Amino-1-methyl-3-propyl-5-pyrazolecarboxamide 1-METHYL-3-PROPYLPYRAZOLE-5-CARBOXYLIC ACID Sildenafil Impurity 25 1-METHYL-3-(2-METHYLPROPYL)-1H-PYRAZOLE-5-CARBOXYLIC ACID 1H-Pyrazole-5-carboxaMide, 1-Methyl-4-[(2-propoxybenzoyl)aMino]-3-propyl- 3-ETHYL-1-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID Sildenafil DiMer IMpurity ETHYL 2,4-DIOXOHEPTANOATE 1-METHYL-3-ISOPROPYL-1H-PYRAZOLE-5-CARBOXYLICACID 5-CHLOROSULFONYL-2-ETHOXYBENZOIC ACID 2-ETHOXY-5-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]BENZOIC ACID Ethyl 5-(tert-butyl)-2H-pyrazole-3-carboxylate 5-TERT-BUTYL-2H-PYRAZOLE-3-CARBOXYLIC ACID ETHYL ESTER ETHYL 3-(TERT-BUTYL)-1-(3-METHYLBENZYL)-1H-PYRAZOLE-5-CARBOXYLATE 5-Pyrazolecarboxylic acid 5-ISOPROPYL-2H-PYRAZOLE-3-CARBOXYLIC ACID

  • ETHYL 5-ISOPROPYLPYRAZOLE-3-CARBOXYLATE, 97
  • 3-ISOPROPYL-1H-PYRAZOLE-5-CARBOXYLICACIDETHYLESTER
  • ethyl 3-(propan-2-yl)-1H-pyrazole-5-carboxylate
  • 1H-Pyrazole-3-carboxylic acid, 5-(1-Methylethyl)-, ethyl ester
  • Ethyl 5-(1-methylethyl)-1H-pyrazole-3-carboxylate
  • 5-Isopropyl-1H-pyrazole-3-carboxylic acid ethyl ester
  • ETHYL 5-ISOPROPYLPYRAZOLE-3-CARBOXYLATE
  • ETHYL-3-ISOPROPYL PYRAZOLE-5-CARBOXYLATE
  • 78208-72-7