3,5-Dibromoanisole
- Product Name
- 3,5-Dibromoanisole
- CAS No.
- 74137-36-3
- Chemical Name
- 3,5-Dibromoanisole
- Synonyms
- 3,5-DibromoanisoL;3,5-DIBROMOANISOLE;3,5-Dibromoanisole>3,5-dibromophenyl ether;Phloroglucinol Impurity 13;1,3-dibromo-5-methoxybenzene;Benzene,1,3-dibroMo-5-Methoxy-
- CBNumber
- CB7511635
- Molecular Formula
- C7H6Br2O
- Formula Weight
- 265.93
- MOL File
- 74137-36-3.mol
3,5-Dibromoanisole Property
- Melting point:
- 34-38 °C
- Boiling point:
- 249.7°C
- Density
- 1.823
- Flash point:
- 98.1°C
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- soluble in Methanol
- form
- powder to crystal
- color
- White to Gray to Brown
- Stability:
- Stable. Incompatible with strong oxidizing agents.
- InChI
- InChI=1S/C7H6Br2O/c1-10-7-3-5(8)2-6(9)4-7/h2-4H,1H3
- InChIKey
- OQZAQBGJENJMHT-UHFFFAOYSA-N
- SMILES
- C1(Br)=CC(OC)=CC(Br)=C1
- CAS DataBase Reference
- 74137-36-3(CAS DataBase Reference)
N-Bromosuccinimide Price
- Product number
- 675830
- Product name
- 3,5-Dibromoanisole
- Purity
- 97%
- Packaging
- 1g
- Price
- $51.45
- Updated
- 2025/07/31
- Product number
- D3364
- Product name
- 3,5-Dibromoanisole
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $44
- Updated
- 2025/07/31
- Product number
- D3364
- Product name
- 3,5-Dibromoanisole
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $169
- Updated
- 2025/07/31
- Product number
- D422970
- Product name
- 3,5-Dibromoanisole
- Packaging
- 10g
- Price
- $165
- Updated
- 2021/12/16
- Product number
- D422970
- Product name
- 3,5-Dibromoanisole
- Packaging
- 2.5g
- Price
- $120
- Updated
- 2021/12/16
3,5-Dibromoanisole Chemical Properties,Usage,Production
Chemical Properties
solid
Uses
3,5-Dibromoanisole, is an organic building block used for the synthesis of various pharmaceutical compounds, such as Dicationic m-Terphenyl and 1,3-Dipyridylbenzene Derivatives, having Antiprotozoal Activity.
Synthesis
67-56-1
6311-60-0
74137-36-3
The general procedure for the synthesis of 3,5-dibromoanisole from methanol and 1,3-dibromo-5-nitrobenzene was as follows: 1,3-dibromo-5-nitrobenzene (21.07 g, 75 mmol), freshly powdered potassium hydroxide (7.57 g, 135 mmol) and tetrabutyl ammonium bromide (2.42 g, 7.5 mmol) were suspended in tetramethylurea (80 mL). A solution of methanol (4.81 g, 6.09 mL, 150 mmol) dissolved in 20 mL of tetramethylurea was added slowly and dropwise to the above brown suspension over a period of 15 min at room temperature. The reaction mixture was stirred continuously for 24 h at room temperature before it was quenched by pouring it into ice (150 g) and extracted with tert-butyl methyl ether (3 x 250 mL). The organic phases were combined, dried with magnesium sulfate and subsequently concentrated under reduced pressure to give the crude product. The crude product was purified by reduced pressure distillation (124 °C, 10 Torr) to give 16.74 g (84% yield) of 3,5-dibromoanisole as a light yellow solid.
References
[1] Patent: US2006/270686, 2006, A1. Location in patent: Page/Page column 35
[2] Journal of Medicinal Chemistry, 2011, vol. 54, # 1, p. 179 - 200
[3] Patent: US2008/280891, 2008, A1. Location in patent: Page/Page column 34-35
[4] Patent: WO2008/8059, 2008, A1. Location in patent: Page/Page column 96
3,5-Dibromoanisole Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3,5-Dibromoanisole manufacturers
- Product
- 3,5-Dibromoanisole 74137-36-3
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- 3,5-Dibromoanisole 74137-36-3
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09
- Product
- 3,5-Dibromoanisole 74137-36-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500kg
- Release date
- 2019-12-25