(-)-4-BROMOTETRAMISOLE OXALATE
- Product Name
- (-)-4-BROMOTETRAMISOLE OXALATE
- CAS No.
- 62284-79-1
- Chemical Name
- (-)-4-BROMOTETRAMISOLE OXALATE
- Synonyms
- (-)-P-BROMOTETRAMISOLE OXALATE;(-)-p-Bromotetramisole oxalate;(S)-6-(p-bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole oxalate;R 30402;6-BROMOLEVAMISOLE OXALATE;L-P-BROMOTETRAMISOLE OXALATE;(-)-P-BROMOLEVAMISOLE OXALATE;(-)-4-BROMOTETRAMISOLE OXALATE;Bromotetramisole, L(-) oxalate;(-)-4-BROMOTETRAMISOLE OXALATE
- CBNumber
- CB7709111
- Molecular Formula
- C13H13BrN2O4S
- Formula Weight
- 373.22
- MOL File
- 62284-79-1.mol
(-)-4-BROMOTETRAMISOLE OXALATE Property
- Melting point:
- 192 °C (dec.) (lit.)
- Flash point:
- 87℃
- storage temp.
- 2-8°C
- solubility
- Soluble in Water (up to 10 mg/ml)
- form
- liquid
- color
- White
- optical activity
- [α]25/D 104°, c = 0.5 in H2O
- BRN
- 4944883
- Stability:
- Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 3 months.
Safety
- Hazard Codes
- Xn
- Risk Statements
- 21/22-36/37/38-20/21/22
- Safety Statements
- 24/25-36/37/39-26
- WGK Germany
- 3
- F
- 10
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
N-Bromosuccinimide Price
- Product number
- 190047
- Product name
- (?)-p-Bromolevamisole oxalate
- Purity
- 99%
- Packaging
- 25mg
- Price
- $68.4
- Updated
- 2024/03/01
- Product number
- 190047
- Product name
- (?)-p-Bromolevamisole oxalate
- Purity
- 99%
- Packaging
- 100mg
- Price
- $462
- Updated
- 2024/03/01
- Product number
- 18713
- Product name
- L-p-Bromotetramisole (oxalate)
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 18713
- Product name
- L-p-Bromotetramisole (oxalate)
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $70
- Updated
- 2024/03/01
- Product number
- 18713
- Product name
- L-p-Bromotetramisole (oxalate)
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $109
- Updated
- 2024/03/01
(-)-4-BROMOTETRAMISOLE OXALATE Chemical Properties,Usage,Production
Description
Four distinct human isoenzymes of alkaline phosphatase (AP) are known: intestinal (IAP), placental (PLAP), tissue non-specific (NSAP, also known as liver/bone/kidney AP), and germ cell AP (also known as placental-like AP, PLAP-like). L-p-Bromotetramisole is a cell-permeable inhibitor of all four human AP isoenzymes (Kis =18 and 56 μM for PLAP and NSAP, respectively). While PLAP is strongly inhibited by L-p-bromotetramisole, a second AP, possibly PLAP-like, shows only partial inhibition. L-p-Bromotetramisole has been shown to inhibit a tyrosine phosphatase from Drosophila and, as a result, is also used as a tyrosine phosphatase inhibitor.
Chemical Properties
white to light yellow crystal powde
Uses
L-p-Bromotetramisole Oxalate or (-)-p-Bromotetramisole Oxalate is a potent inhibitor of alkaline phosphatase.
Biochem/physiol Actions
(-)-p-Bromolevamisole oxalate inhibits L-isoforms of alkaline phosphatases.
target
alkaline phosphatase
References
1) Kovach?et al. (1992),?Levamisole potentiation of fluorouracil antiproliferative activity mimicked by orthovanadate, an inhibitor of tyrosine phosphatase; J. Natl. Cancer Inst.,?84?515 2) Luo et al. (2000),?Role of protein phosphatases in the activation of CTFR (ABCC7) by genistein and bromotetramisole;?Am. J. Physiol. Cell Physiol.,?279?C108 3) Scher?et al.?(1998),?The phosphatase inhibitors, orthovanadate and levamisole, inhibit induction of erythroid differentiation and abrogate the associated inhibition of glycolysis; Int. J. Oncol.,?12?987
(-)-4-BROMOTETRAMISOLE OXALATE Preparation Products And Raw materials
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View Lastest Price from (-)-4-BROMOTETRAMISOLE OXALATE manufacturers
- Product
- (-)-4-BROMOTETRAMISOLE OXALATE 62284-79-1
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 100 Tons min
- Release date
- 2021-08-18
- Product
- (-)-4-BROMOTETRAMISOLE OXALATE 62284-79-1
- Price
- US $3.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2020-02-01