H-LEU-4M-BETANA HCL
- Product Name
- H-LEU-4M-BETANA HCL
- CAS No.
- 4467-68-9
- Chemical Name
- H-LEU-4M-BETANA HCL
- Synonyms
- H-Leu-4MbNA·HCl;H-Leu-4MβNA · HCl;H-LEU-4M-BETANA HCL;LEUCINE-4M-BETANA HCL;H-Leu-4MβNA (hydrochloride);L-LEU-4-METHOXY-BETA-NAPHTHYLAMIDE HCL;L-LEUCYL-4-METHOXY-B-NAPHTHYLAMIDE HYDROCHLORIDE;L-leucine 4-methoxy-B-naphthylamide*hydrochloride;L-Leucine 4-methoxy-β-naphthylamide (hydrochloride);L-Leucine 4-methoxy-β-naphthylamide hydrochloride
- CBNumber
- CB7743373
- Molecular Formula
- C17H23ClN2O2
- Formula Weight
- 322.83
- MOL File
- 4467-68-9.mol
H-LEU-4M-BETANA HCL Property
- storage temp.
- 2-8°C
- solubility
- ≤25mg/ml in ethanol;10mg/ml in DMSO;20mg/ml in dimethyl formamide
- form
- crystalline solid
N-Bromosuccinimide Price
- Product number
- 16223
- Product name
- L-Leucine 4-methoxy-β-naphthylamide (hydrochloride)
- Purity
- ≥98%
- Packaging
- 100mg
- Price
- $55
- Updated
- 2024/03/01
- Product number
- 16223
- Product name
- L-Leucine 4-methoxy-β-naphthylamide (hydrochloride)
- Purity
- ≥98%
- Packaging
- 1g
- Price
- $358
- Updated
- 2024/03/01
- Product number
- 16223
- Product name
- L-Leucine 4-methoxy-β-naphthylamide (hydrochloride)
- Purity
- ≥98%
- Packaging
- 250mg
- Price
- $96
- Updated
- 2024/03/01
- Product number
- C3708
- Product name
- L-Leucine4-methoxy-β-naphthylamide(hydrochloride)
- Packaging
- 250mg
- Price
- $177
- Updated
- 2021/12/16
- Product number
- 3484AL
- Product name
- L-Leucine4-methoxy-beta-naphthylamidehydrochloride
- Packaging
- 250mg
- Price
- $272
- Updated
- 2021/12/16
H-LEU-4M-BETANA HCL Chemical Properties,Usage,Production
Description
L-Leucine 4-methoxy-β-naphthylamide is a cell-permeable substrate for aminopeptidase M and leucine aminopeptidase that was developed for intracellular analysis of protease activities.
Chemical Properties
Crystalline
Uses
L-Leucine 4-methoxy-β-naphthylamide is a cell-permeable substrate for aminopeptidase M and leucine aminopeptidase that was developed for intracellular analysis of protease activities.
in vitro
l-leucine 4-methoxy-β-naphthylamide was identified as a cell-permeable substrate for aminopeptidase m and leucine aminopeptidase that was developed for intracellular analysis of protease activities [1]. in a previous method-developing study, peptide derivatives of 4-methoxy-β-naphthylamine including l-leucine 4-methoxy-β-naphthylamide were incubated in microtiter plates together with nitrosalicylaldehyde. selectivity was achieved by running parallel assays containing inhibitors partially selective for each of peptide derivatives. this method was successfully validated by measurements in cells isolated from cathepsin b-/--, k-/--, and l-/-- mice [2].
References
[1] monis, b. ,wasserkrug, h. and seligman, a.m. comparison of fixatives and substrates for aminopeptidase. journal of histochemistry and cytochemistry 13(6), 503-509 (1965).
[2] rüttger, a. ,mollenhauer, j.,lser, r., et al. microplate assay for quantitative determination of cathepsin activities in viable cells using derivatives of 4-methoxy-β-naphthylamide. biotechniques 41(4), 469-473 (2006).
H-LEU-4M-BETANA HCL Preparation Products And Raw materials
Raw materials
Preparation Products
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