ChemicalBook > CAS DataBase List > H-LEU-4M-BETANA HCL

H-LEU-4M-BETANA HCL

Product Name
H-LEU-4M-BETANA HCL
CAS No.
4467-68-9
Chemical Name
H-LEU-4M-BETANA HCL
Synonyms
H-Leu-4MbNA·HCl;H-Leu-4MβNA · HCl;H-LEU-4M-BETANA HCL;LEUCINE-4M-BETANA HCL;H-Leu-4MβNA (hydrochloride);L-LEU-4-METHOXY-BETA-NAPHTHYLAMIDE HCL;L-LEUCYL-4-METHOXY-B-NAPHTHYLAMIDE HYDROCHLORIDE;L-leucine 4-methoxy-B-naphthylamide*hydrochloride;L-Leucine 4-methoxy-β-naphthylamide (hydrochloride);L-Leucine 4-methoxy-β-naphthylamide hydrochloride
CBNumber
CB7743373
Molecular Formula
C17H23ClN2O2
Formula Weight
322.83
MOL File
4467-68-9.mol
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H-LEU-4M-BETANA HCL Property

storage temp. 
2-8°C
solubility 
≤25mg/ml in ethanol;10mg/ml in DMSO;20mg/ml in dimethyl formamide
form 
crystalline solid
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Safety

Hazard Codes 
Xn
Risk Statements 
40
Safety Statements 
22-36
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H351Suspected of causing cancer

Precautionary statements

P281Use personal protective equipment as required.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
16223
Product name
L-Leucine 4-methoxy-β-naphthylamide (hydrochloride)
Purity
≥98%
Packaging
100mg
Price
$55
Updated
2024/03/01
Cayman Chemical
Product number
16223
Product name
L-Leucine 4-methoxy-β-naphthylamide (hydrochloride)
Purity
≥98%
Packaging
1g
Price
$358
Updated
2024/03/01
Cayman Chemical
Product number
16223
Product name
L-Leucine 4-methoxy-β-naphthylamide (hydrochloride)
Purity
≥98%
Packaging
250mg
Price
$96
Updated
2024/03/01
ApexBio Technology
Product number
C3708
Product name
L-Leucine4-methoxy-β-naphthylamide(hydrochloride)
Packaging
250mg
Price
$177
Updated
2021/12/16
AK Scientific
Product number
3484AL
Product name
L-Leucine4-methoxy-beta-naphthylamidehydrochloride
Packaging
250mg
Price
$272
Updated
2021/12/16
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H-LEU-4M-BETANA HCL Chemical Properties,Usage,Production

Description

L-Leucine 4-methoxy-β-naphthylamide is a cell-permeable substrate for aminopeptidase M and leucine aminopeptidase that was developed for intracellular analysis of protease activities.

Chemical Properties

Crystalline

Uses

L-Leucine 4-methoxy-β-naphthylamide is a cell-permeable substrate for aminopeptidase M and leucine aminopeptidase that was developed for intracellular analysis of protease activities.

in vitro

l-leucine 4-methoxy-β-naphthylamide was identified as a cell-permeable substrate for aminopeptidase m and leucine aminopeptidase that was developed for intracellular analysis of protease activities [1]. in a previous method-developing study, peptide derivatives of 4-methoxy-β-naphthylamine including l-leucine 4-methoxy-β-naphthylamide were incubated in microtiter plates together with nitrosalicylaldehyde. selectivity was achieved by running parallel assays containing inhibitors partially selective for each of peptide derivatives. this method was successfully validated by measurements in cells isolated from cathepsin b-/--, k-/--, and l-/-- mice [2].

References

[1] monis, b. ,wasserkrug, h. and seligman, a.m. comparison of fixatives and substrates for aminopeptidase. journal of histochemistry and cytochemistry 13(6), 503-509 (1965).
[2] rüttger, a. ,mollenhauer, j.,lser, r., et al. microplate assay for quantitative determination of cathepsin activities in viable cells using derivatives of 4-methoxy-β-naphthylamide. biotechniques 41(4), 469-473 (2006).

H-LEU-4M-BETANA HCL Preparation Products And Raw materials

Raw materials

Preparation Products

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H-LEU-4M-BETANA HCL Suppliers

Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15402
Advantage
60
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
BOC Sciences
Tel
16314854226; +16314854226
Email
inquiry@bocsci.com
Country
United States
ProdList
19741
Advantage
58
Nextpeptide Inc
Tel
+86-0571-81612335 +8613336028439
Email
sales@nextpeptide.com
Country
China
ProdList
19908
Advantage
58
Jiangsu Hongmin Pharmaceutical Co., Ltd.
Tel
18221292452
Email
fannieliu@glschina.com
Country
China
ProdList
6798
Advantage
58
MedBioPharmaceutical Technology Inc
Tel
021-69568360 18916172912
Email
order@med-bio.cn
Country
China
ProdList
8140
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing@energy-chemical.com
Country
China
ProdList
44918
Advantage
58
TCI (Shanghai) Chemical Trading Co., Ltd.
Tel
021-021-61109150
Fax
021-61105897
Email
sales@tcisct.com
Country
China
ProdList
31121
Advantage
58
Shanghai Yiyan Biotechnology Co. , Ltd.
Tel
021-69985186 13611928337
Email
3427709316@qq.com
Country
China
ProdList
7978
Advantage
58

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