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trans-Chalcone

Product Name
trans-Chalcone
CAS No.
614-47-1
Chemical Name
trans-Chalcone
Synonyms
(E)-CHALCONE;BENZALACETOPHENONE;cone;BENZYLIDENEACETOPHENONE;1,3-DIPHENYL-2-PROPEN-1-ONE;CHALKONE;1,3-DIPHENYL-2-PROPENONE;2-Propen-1-one, 1,3-diphenyl-, (E)-;Nsc167107;trans-ChaL
CBNumber
CB7746253
Molecular Formula
C15H12O
Formula Weight
208.26
MOL File
614-47-1.mol
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trans-Chalcone Property

Melting point:
55-59 °C
Boiling point:
208 °C25 mm Hg(lit.)
Density 
1.0712
refractive index 
1.5361 (estimate)
Flash point:
>230 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly)
form 
Solid
color 
Pale Yellow
Odor
at 100.00 %. floral balsam herbal
Odor Type
floral
Water Solubility 
Soluble in chloroform, ether, benzene, and ethanol (slightly). Insoluble in water.
Merck 
14,2037
BRN 
509985
LogP
4.013 (est)
CAS DataBase Reference
614-47-1(CAS DataBase Reference)
NIST Chemistry Reference
Benzalacetophenone(614-47-1)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-36/37
Safety Statements 
22-36/37/39-45
WGK Germany 
3
RTECS 
UD5576750
HS Code 
29143990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
136123
Product name
trans-Chalcone
Purity
97%
Packaging
5g
Price
$42.7
Updated
2024/03/01
Sigma-Aldrich
Product number
136123
Product name
trans-Chalcone
Purity
97%
Packaging
100g
Price
$62.4
Updated
2024/03/01
Alfa Aesar
Product number
A14734
Product name
trans-Chalcone, 97%
Packaging
100g
Price
$53
Updated
2024/03/01
Alfa Aesar
Product number
A14734
Product name
trans-Chalcone, 97%
Packaging
500g
Price
$175
Updated
2024/03/01
TRC
Product number
C291860
Product name
trans-Chalcone
Packaging
5g
Price
$65
Updated
2021/12/16
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trans-Chalcone Chemical Properties,Usage,Production

Description

trans-Chalcone is an open chain flavonoid that may prevent lung and forestomach cancer.

Chemical Properties

Trans-Chalcone is a yellowish crystals. M.P. 58℃. (trans-isomer). M .P. 46℃. (cis-isomer).Sp.Gr. 1.07 (liquid).Insoluble in water, soluble in alcohol (poorly) and oils.

Uses

trans-Chalcone is a positive allosteric modulator of α7 nicotinic acetylcholine receptors and exhibits antioxidant activity.

Definition

ChEBI: Chalcone is a member of the class of chalcones that is acetophenone in which one of the methyl hydrogens has been replaced by a benzylidene group. It has a role as a plant metabolite. It is a member of styrenes and a member of chalcones.

Application

trans-Chalcone was used in the synthesis of cis and trans diphenyl cyclopropane. It was also used in screening of surface adsorbed species of isobutybenzene and 4-isobutylacetophenone on bulk fosfotungstic Wells-Dawson acid (H6P2W18O62.xH2O).

Preparation

trans-Chalcones have been obtained in good yields and selectivities following an environmentally friendly methodology by using montmorillonite KSF as a reusable heterogeneous catalyst.
Clay-catalysed solventless synthesis of trans-chalcones

Synthesis Reference(s)

Journal of the American Chemical Society, 104, p. 4724, 1982 DOI: 10.1021/ja00381a058

General Description

trans-Chalcone is an open chain flavonoid that may prevent lung and forestomach cancer.

Biological Activity

trans-Chalcone exhibits antifungal activity against Trichophyton rubrum. It is inhibitor of fatty acid synthase and α-amylase. It induces programmed cell death due to reduced mitochondrial transmembrane potential in Arabidopsis thaliana roots.

Biochem/physiol Actions

trans-Chalcone exhibits antifungal activity against Trichophyton rubrum. It is inhibitor of fatty acid synthase and α-amylase. It induces programmed cell death due to reduced mitochondrial transmembrane potential in Arabidopsis thaliana roots.

Synthesis

Trans-Chalcone is synthesized by condensation of Benzaldehyde with Acetophenone.

trans-Chalcone Preparation Products And Raw materials

Raw materials

Preparation Products

α-Naphthoflavone Chalcone 3,5-DIPHENYLPYRAZOLE
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trans-Chalcone Suppliers

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View Lastest Price from trans-Chalcone manufacturers

Hebei Kingfiner Technology Development Co.Ltd
Product
trans-Chalcone 614-47-1
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
50000kg
Release date
2024-06-18
Career Henan Chemical Co
Product
trans-Chalcone 614-47-1
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000kgs
Release date
2020-01-02

614-47-1, trans-ChalconeRelated Search:

PROPYLENE tert-Butylchlorodiphenylsilane trans,trans-2,4-Undecadienal 1,3-Diphenyl-2-thiourea DIPHENYLCYCLOPROPENONE Dichlorodiphenylsilane Diphenylphosphine Biphenyl Diphenylsilane Diphenylmethane Chlorodiphenylphosphine Neosperidin dihydrochalcone 3-HYDROXYFLAVONE Galangin 7,8-Dihydroxyflavone α-Naphthoflavone 4'-METHOXYCHALCONE Apigenin

  • PHENYL STYRYL KETONE
  • (2E)-1,3-DIPHENYLPROP-2-EN-1-ONE
  • 2-BENZALACETOPHENONE
  • 2-BENZYLIDENEACETOPHENONE
  • 3-PHENYLACRYLOPHENONE
  • TRANS-BENZYLIDENEACETOPHENONE
  • TRANS-CHALCONE
  • 1,3-DIPHENYL-2-PROPEN-1-ONE
  • 1,3-DIPHENYL-2-PROPEN-I-ONE
  • 1,3-DIPHENYL-2-PROPENONE
  • 1,3-DIPHENYL-3-PROPEN-1-ONE
  • 1,3-DIPHENYLPROP-2-EN-1-ONE
  • phenyltrans-styrylketone
  • trans-benzalacetophenone
  • (e)-1,3-diphenyl-2-propen-1-one
  • (e)-benzylideneacetophenone
  • 2-Propen-1-one, 1,3-diphenyl-, (E)-
  • 3-diphenyl-(e)-2-propen-1-on
  • phenyl(e)-2-phenylethenylketone
  • cone
  • trans-ChaL
  • Chalcone(BenzalAcetophenone)
  • CHALKONE
  • (E)-CHALCONE
  • BENZYLIDENEACETOPHENONE
  • BENZYLIDINEACETOPHENONE
  • BENZALACETOPHENONE
  • (E)-1,3-Diphenylpropen-3-one
  • (E)-1-Benzoyl-2-phenylethylene
  • trans-1,3-Diphenyl-2-propen-1-one
  • (αE)-β-Phenylacrylophenone
  • (βE)-β-Phenylacrylophenone
  • Phenyl[(E)-styryl] ketone
  • trans-Benzalacetophenone, (E)-1,3-Diphenylprop-2-en-1-one
  • Nsc167107
  • trans-Chalcone 97%
  • <i>trans</i>-Chalcone
  • 2-Propen-1-one, 1,3-diphenyl-, (2E)-
  • rans-chalcone
  • Benzylidence aceptophenone (Chalcone-97%)
  • trans-Chalcone 614-47-1
  • Chalcone|||Cinnamophenone|||Chalkone
  • 614-47-1
  • C6H5COCHCHC6H5
  • Organic Building Blocks
  • Ketones
  • Building Blocks
  • Carbonyl Compounds
  • C15 to C38
  • Flavonoids