6-Mercaptohexan-1-ol Property

Boiling point:

225 °C(lit.)

Density 

0.981 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.486(lit.)

Flash point:

>230 °F

storage temp. 

Inert atmosphere,Room Temperature

solubility 

Chloroform (Sparingly), Methanol (Slightly)

pka

10.47±0.10(Predicted)

form 

liquid

color 

Colourless

BRN 

1846871

Stability:

Air Sensitive

InChI

InChI=1S/C6H14OS/c7-5-3-1-2-4-6-8/h7-8H,1-6H2

InChIKey

UGZAJZLUKVKCBM-UHFFFAOYSA-N

SMILES

C(O)CCCCCS

LogP

1.370 (est)

EPA Substance Registry System

1-Hexanol, 6-mercapto- (1633-78-9)

Safety

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

RIDADR 

UN 3334

WGK Germany 

3

F 

10-13-23

HS Code 

29309090

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

6-Mercaptohexan-1-ol Chemical Properties,Usage,Production

Chemical Properties

Colorless to light yellow liquid

Uses

6-Mercapto-1-hexanolcan be used as a chemical linker for anchoring biological molecules to gold surfaces.

Uses

This compound is used to produce hydrophilic SAMs. The resulting monolayers which are terminated with alcohols can be further functionalized with various groups even when attached to gold nanoclusters.

Uses

MCH is coated on a piezoelectric crystal which can be used for the fabrication of chemical sensor to differentiate between cheese varieties. Self assembled monolayers of MCH can be used on gold surfaces for bio-sensing applications. It can also be used as a monolayer for the surface modification of gold-polyaniline (Au-PANI) nanocomposites for the development of aptamer based biosensors (aptasensors).

General Description

6-mecapto-1-hexanol (MCH) forms a self-assembled monolayer (SAM) with identically represented C6 spacer. MCH is a tool for surface coating that enables blocking of active sites and non-specific absorption.