ChemicalBook > CAS DataBase List > Thalidomide-NH-C6-NH2 TFA
Thalidomide-NH-C6-NH2 TFA
- Product Name
- Thalidomide-NH-C6-NH2 TFA
- CAS No.
- 2093386-51-5
- Chemical Name
- Thalidomide-NH-C6-NH2 TFA
- Synonyms
- Thalidomide-NH-C6-NH2 TFA;Pomalidomide Related Compound 11 Triflate;4-((6-Aminohexyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione 2,2,2-trifluoroacetate
- CBNumber
- CB78054835
- Molecular Formula
- C21H25F3N4O6
- Formula Weight
- 486.45
- MOL File
- 2093386-51-5.mol
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Thalidomide-NH-C6-NH2 TFA Property
- solubility
- Soluble in DMSO
- form
- Solid
- color
- Light yellow to yellow
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Thalidomide-NH-C6-NH2 TFA Chemical Properties,Usage,Production
Biological Activity
Thalidomide-NH-C6-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].
References
[1]. Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Sep 12;62(17):8152-8163.
Thalidomide-NH-C6-NH2 TFA Preparation Products And Raw materials
Raw materials
Preparation Products
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Thalidomide-NH-C6-NH2 TFA Suppliers
- Tel
- --
- Fax
- --
- mktg@pharmaffiliates.com
- Country
- India
- ProdList
- 6739
- Advantage
- 58
2093386-51-5, Thalidomide-NH-C6-NH2 TFARelated Search:
Thalidomide-O-amido-C2-NH2
4-((2-(2-(2-aminoethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
2-(2,6-dioxopiperidin-3-yl)-4-(prop-2-yn-1-yloxy)isoindoline-1,3-dione
-alkylC5-amine
4-[(6-Aminohexyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl
E3 ligase Ligand-Linker Conjugates 15
Thalidomide-O-amido-C2-NH2
Thalidomide-NH-C4-NH-Boc
Thalidomide-NH-C4-NH2 TFA
Thalidomide-NH-PEG2-C2-NH2 hydrochloride
Thalidomide-NH-PEG2-C2-NH2 (TFA)