Lucatumumab

Product Name: Lucatumumab
CAS No.: 903512-50-5
Chemical Name: Lucatumumab
Synonyms: Lucatumumab;Lucatumumab (anti-CD40);Research Grade Lucatumumab;Research Grade Lucatumumab(DHD68905)
CBNumber: CB78080760
Formula Weight: 0
MOL File: Mol file

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Lucatumumab Property

storage temp.: Store at -20°C
form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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Lucatumumab Chemical Properties,Usage,Production

Uses

Lucatumumab (HCD122) is a fully human anti-CD40 antagonist monoclonal antibody, which blocks CD40/CD40L-mediated signaling. Lucatumumab efficiently mediates antibody-dependent cell-mediated cytotoxicity (ADCC) and clearance of tumor cells, can be used for refractory lymphomas, CLL and multiple myeloma research[1][2].

IC 50

CD40

References

[1] Luqman M, et al. The antileukemia activity of a human anti-CD40 antagonist antibody, HCD122, on human chronic lymphocytic leukemia cells. Blood. 2008 Aug 1;112(3):711-20. DOI:10.1182/blood-2007-04-084756
[2] Drgona L, et al. ESCMID Study Group for Infections in Compromised Hosts (ESGICH) Consensus Document on the safety of targeted and biological therapies: an infectious diseases perspective (Agents targeting lymphoid or myeloid cells surface antigens [II]: CD22, CD30, CD33, CD38, CD40, SLAMF-7 and CCR4). Clin Microbiol Infect. 2018 Jun;24 Suppl 2:S83-S94. DOI:10.1016/j.cmi.2018.03.022

Lucatumumab Preparation Products And Raw materials

Raw materials

Preparation Products

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Lucatumumab Suppliers

China 13 Global 13

Shanghai YuanYe Biotechnology Co., Ltd.

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Wuhan Chemstan Biotechnology Co., Ltd.

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TargetMol Chemicals Inc.

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Biolab Reagents

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Shanghai Yifei Biotechnology Co. , Ltd.

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Atagenix Laboratories

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AntibodySystem Laboratories SAS

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Biosynth Biological Technology (Suzhou) Co Ltd

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Cell Sciences

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903512-50-5, LucatumumabRelated Search:

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Lucatumumab

Research Grade Lucatumumab(DHD68905)

Research Grade Lucatumumab

Lucatumumab (anti-CD40)

903512-50-5