ChemicalBook > CAS DataBase List > Ethyl 3-(pyridin-2-ylamino)propanoate
Ethyl 3-(pyridin-2-ylamino)propanoate
- Product Name
- Ethyl 3-(pyridin-2-ylamino)propanoate
- CAS No.
- 103041-38-9
- Chemical Name
- Ethyl 3-(pyridin-2-ylamino)propanoate
- Synonyms
- Dabigatran Impurity 83;3-(Pyridin-2-ylamino)propanoate;Dabigatran Etexilate Impurity 90;N-[2]PYRIDYL-B-ALANIN-ETHYL ESTER;Ethyl 3-(pyridin-2-ylamino)propan;Ethyl 3-(2-PyridylaMino)propanoate;N-2-pyridinyl-β-Alanine,ethylester;Dabigatran Etexilate Intermdiate 4;Ethyl 3-(2-Pyridylamino)propionate;N-2-Pyridinyl-β-Alanine,ethylester
- CBNumber
- CB81011425
- Molecular Formula
- C10H14N2O2
- Formula Weight
- 194.23
- MOL File
- 103041-38-9.mol
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Ethyl 3-(pyridin-2-ylamino)propanoate Property
- Melting point:
- 48-50°C
- Boiling point:
- 125°C/0.2mmHg(lit.)
- Density
- 1.131±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,2-8°C
- solubility
- DMSO, Methanol
- form
- Solid
- pka
- 6.26±0.10(Predicted)
- color
- White
- InChI
- InChI=1S/C10H14N2O2/c1-2-14-10(13)6-8-12-9-5-3-4-7-11-9/h3-5,7H,2,6,8H2,1H3,(H,11,12)
- InChIKey
- UITNIDFEANEWPC-UHFFFAOYSA-N
- SMILES
- C(OCC)(=O)CCNC1C=CC=CN=1
- LogP
- 1.54 at 22℃ and pH6
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Safety
- HS Code
- 2933.39.9200
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N-Bromosuccinimide Price
TCI Chemical
- Product number
- E1214
- Product name
- Ethyl 3-(2-Pyridylamino)propionate
- Purity
- >98.0%(T)
- Packaging
- 5g
- Price
- $27
- Updated
- 2024/03/01
TCI Chemical
- Product number
- E1214
- Product name
- Ethyl 3-(2-Pyridylamino)propionate
- Purity
- >98.0%(T)
- Packaging
- 25g
- Price
- $79
- Updated
- 2024/03/01
TRC
- Product number
- E925620
- Product name
- Ethyl3-(Pyridin-2-ylamino)propanoate
- Packaging
- 10g
- Price
- $110
- Updated
- 2021/12/16
TRC
- Product number
- E925620
- Product name
- Ethyl3-(Pyridin-2-ylamino)propanoate
- Packaging
- 1g
- Price
- $45
- Updated
- 2021/12/16
TRC
- Product number
- E925620
- Product name
- Ethyl3-(Pyridin-2-ylamino)propanoate
- Packaging
- 5g
- Price
- $70
- Updated
- 2021/12/16
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Ethyl 3-(pyridin-2-ylamino)propanoate Chemical Properties,Usage,Production
Chemical Properties
White Solid
Uses
Dabigatran etexilate intermediate
Uses
Ethyl 3-(2-Pyridylamino)propanoate is an intermediate used in the synthesis of Dabigatran etexilate, as thrombin inhibitors. Ethyl Ester form of P993315.
Synthesis
A method for preparing Ethyl 3-(pyridin-2-ylamino)propanoate comprises the following steps: using 2-aminopyridine and ethyl acrylate as raw materials, using anhydrous ethanol as a solvent, using trifluoromethanesulfonic acid as a catalyst, and heating in an oil bath to control the temperature at 120 to 160° C. for a catalytic reaction for 16 to 20 hours under nitrogen protection. The obtained reaction solution is washed with petroleum ether at a temperature of 35 to 40° C. and a pressure of 0.09 to 0.1 MPa, then concentrated under reduced pressure, and then washed with petroleum ether/ethyl acetate and recrystallized to obtain white flaky crystals of Ethyl 3-(pyridin-2-ylamino)propanoate.
Ethyl 3-(pyridin-2-ylamino)propanoate Preparation Products And Raw materials
Raw materials
Preparation Products
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Ethyl 3-(pyridin-2-ylamino)propanoate Suppliers
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View Lastest Price from Ethyl 3-(pyridin-2-ylamino)propanoate manufacturers
Hebei Chuanghai Biotechnology Co,.LTD
- Product
- Ethyl 3- (pyridin-2-ylamino) Propanoate 103041-38-9
- Price
- US $5.00-2.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10000kg
- Release date
- 2024-08-21
Zibo Wei Bin Import & Export Trade Co. Ltd.
- Product
- N-[2]PYRIDYL-B-ALANIN-ETHYL ESTER 103041-38-9
- Price
- US $100.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 1T
- Release date
- 2023-07-18
Henan Fengda Chemical Co., Ltd
- Product
- N-[2]PYRIDYL-B-ALANIN-ETHYL ESTER 103041-38-9
- Price
- US $5.00-0.10/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-16
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