ChemicalBook > CAS DataBase List > Pamidronic acid

Pamidronic acid

Product Name
Pamidronic acid
CAS No.
40391-99-9
Chemical Name
Pamidronic acid
Synonyms
DLV;AHPrBP;Panolin;amidronate;Rescriptor;Pamidronicaci;PAMIDRONIC ACID;Iflab-bb F1977-0047;Delavirdine mesylate;Ibandronate Impurity 23
CBNumber
CB8107554
Molecular Formula
C3H11NO7P2
Formula Weight
235.07
MOL File
40391-99-9.mol
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Pamidronic acid Property

Melting point:
226-228°C
Boiling point:
658.7±65.0 °C(Predicted)
Density 
1.998±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
solubility 
Methanol (Very Slightly, Heated, Sonicated), Water (Slightly, Heated, Sonicated)
pka
1.44±0.10(Predicted)
form 
Solid
color 
Light Brown to Beige
Stability:
Hygroscopic
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Safety

HS Code 
9999999999
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Tocris
Product number
4149
Product name
Delavirdine mesylate
Purity
≥99%(HPLC)
Packaging
50
Price
$634
Updated
2021/12/16
TRC
Product number
P172490
Product name
PamidronicAcid
Packaging
50mg
Price
$105
Updated
2021/12/16
Usbiological
Product number
462007
Product name
Pamidronic Acid
Packaging
50mg
Price
$368
Updated
2021/12/16
AK Scientific
Product number
2631AH
Product name
Pamidronicacid
Packaging
1g
Price
$158
Updated
2021/12/16
Biorbyt Ltd
Product number
orb134480
Product name
Pamidronic acid
Purity
>99%
Packaging
100mg
Price
$510
Updated
2021/12/16
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Pamidronic acid Chemical Properties,Usage,Production

Chemical Properties

White Solid

Originator

Aredia,Novartis,India

Uses

A biphosphonate bone resorption inhibitor.

Uses

anticancer

Definition

ChEBI: Pamidronate is a phosphonoacetic acid.

Manufacturing Process

For a batch size of 5 L, 587.5 g (3.2 moles) of mannitol is dissolved in 3.5 L of water. Pamidronic acid (31.6 g, 0.133 moles) is mixed with a 1.0 L aliquot of the mannitol solution to form a slurry. The slurry is then transferred into the remainder of the mannitol solution, and stirred for at least 15 min. Aqueous 1 N sodium hydroxide (270 ml) is then added and the mixture is stirred until a clear, colorless solution results. The pH is then adjusted to 6.50.1 using either 1 M aqueous phosphoric acid or 1 N aqueous sodium hydroxide, as needed. The solution is then filtered through a 0.22 micron filter, and filled at 20°C into vials at 4.0 ml (4.172 g)/vial, under sterile conditions. The aqueous solution is frozen at -37°C and lyophilized (20 mbar, 20°-40°C) to yield 1,250 vials, each containing 30 mg of amorphous disodium pamidronate. The vials are sealed under positive nitrogen pressure. The disodium pamidronate is amorphous (noncrystalline) by X-ray diffraction and contains 0.7 wt-% water.

brand name

Rescriptor (Agouron).

Therapeutic Function

Bone resorption suppressant

Pamidronic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Pamidronic acid Suppliers

UHN Shanghai Research & Development Co., Ltd.
Tel
021-58958002 18930822973
Fax
021-58958618
Email
xiaoyangw@gmail.com
Country
China
ProdList
2129
Advantage
58
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
Chembest Research Laboratories Limited
Tel
021-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6013
Advantage
61
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9984
Advantage
60
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10194
Advantage
62
LGM Pharma
Tel
1-(800)-881-8210
Fax
615-250-9817
Email
inquiries@lgmpharma.com
Country
United States
ProdList
2127
Advantage
70
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7815
Advantage
57
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
sales@meilune.com
Country
China
ProdList
4647
Advantage
58
S.Z. PhyStandard Bio-Tech. Co., Ltd.
Tel
4000505016; 13380397412
Fax
0755 28094224
Email
3001272453@qq.com
Country
China
ProdList
5000
Advantage
50
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View Lastest Price from Pamidronic acid manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Pamidronic acid 40391-99-9
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
10kg/month
Release date
2021-06-21
Dideu Industries Group Limited
Product
Pamidronic acid 40391-99-9
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons min
Release date
2021-07-28

40391-99-9, Pamidronic acid Related Search:


  • PAMIDRONIC ACID
  • PAMIDRONIC ACID SODIUM SALT
  • Rescriptor
  • amidronate
  • DLV
  • (3-amino-1-hydroxypropylidene)bisphosphonic acid
  • (3-Amino-1-hydroxypropylidene)diphosphonic acid
  • 3-AMINO-1-HYDROXY-1,1-PROPANEDIPHOSPHONIC ACID
  • Delavirdine mesylate
  • AHPrBP
  • (3-Amino-1-hydroxypropylidene)-1,1-bisphosphonate
  • 3-Amino-1-hydroxypropane-1,1-diphosphonic acid
  • Panolin
  • Propane-1-hydroxy-3-amino-1,1-diphosphonic acid
  • [2-Aminoethyl(hydroxy)methylene]bisphosphonic acid
  • 1-Hydroxy-3-aminopropylidenebis(phosphonic acid)
  • 1-Hydroxy-3-aminopropylidenebisphosphonic acid
  • Iflab-bb F1977-0047
  • PaMidronic acid(Delavirdine Mesylate,Rescriptor)
  • (3-amino-1-hydroxypropane-1,1-diyl)diphosphonic acid
  • Ibandronate Impurity 23
  • Pamidronic acid-d3 major
  • Pamidronicaci
  • Pamidronic acid USP/EP/BP
  • Phosphonic acid, P,P'-(3-amino-1-hydroxypropylidene)bis-
  • (3-Amino-1-hydroxypropane-1,1-diyl)bis(phosphonic acid)
  • 40391-99-9
  • C3H11NO7P2
  • C3H19NNa2O7P2
  • (intermediate of pamidronate disodium)
  • Delavirdine
  • API