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Sodium thiosulfate pentahydrate

Product Name
Sodium thiosulfate pentahydrate
CAS No.
10102-17-7
Chemical Name
Sodium thiosulfate pentahydrate
Synonyms
SODIUM THIOSULPHATE;HYPO;SODIUM THIOSULFATE SOLUTION;Sodium Thiosulfate Hydrate;1kg;4-MPH;SODIUM THIOSULFATE 5 H2O;SodiuM thiosulfate pentahydra;SODIUM THIOSULPHATE PENTAHYDRATE;16g
CBNumber
CB8108182
Molecular Formula
H10Na2O8S2
Formula Weight
248.18
MOL File
10102-17-7.mol
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Sodium thiosulfate pentahydrate Property

Melting point:
48.5 °C
Boiling point:
100 C
Density 
1.01 g/mL at 25 °C
storage temp. 
Store at +5°C to +30°C.
solubility 
H2O: 1 M at 20 °C, clear, colorless
form 
Solid
Specific Gravity
1.729
color 
White tranparent
Odor
Odorless
PH Range
6 - 8.5
PH
6.0-7.5 (100g/l, H2O, 20℃)
Water Solubility 
680 g/L (20 ºC)
Merck 
14,8694
Stability:
Stable. Incompatible with strong acids, iodine, mercury.
InChIKey
AKHNMLFCWUSKQB-UHFFFAOYSA-L
LogP
-0.428 (est)
CAS DataBase Reference
10102-17-7(CAS DataBase Reference)
EPA Substance Registry System
Thiosulfuric acid (H2S2O3), disodium salt, pentahydrate (10102-17-7)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
24/25-37/39-36-26
WGK Germany 
1
RTECS 
WE6660000
F 
10
TSCA 
Yes
HS Code 
28323000
Toxicity
LD50 orally in Rabbit: > 5000 mg/kg
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
13479
Product name
Sodium thiosulfate pentahydrate
Purity
puriss., meets analytical specification of Ph. Eur., BP, USP
Packaging
500G
Price
$61.3
Updated
2024/03/01
Sigma-Aldrich
Product number
13479
Product name
Sodium thiosulfate pentahydrate
Purity
puriss., meets analytical specification of Ph. Eur., BP, USP
Packaging
2.5KG
Price
$231
Updated
2024/03/01
Sigma-Aldrich
Product number
1.09147
Product name
Sodium thiosulfate solution
Purity
c(Na?S?O? 5 H?O) = 0.1 mol/l (0.1 N) Titripur? Reag. Ph Eur,Reag. USP
Packaging
1L
Price
$32.4
Updated
2024/03/01
Sigma-Aldrich
Product number
1.60318
Product name
Sodium thiosulfate solution
Purity
0.01?M Na2S2O3 (0.01 N), Titripur?
Packaging
1L
Price
$30.5
Updated
2024/03/01
Sigma-Aldrich
Product number
1.60311
Product name
Sodium thiosulfate solution
Purity
0.05?M Na2S2O3 (0.05 N), Titripur?
Packaging
1L
Price
$31.5
Updated
2024/03/01
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Sodium thiosulfate pentahydrate Chemical Properties,Usage,Production

Chemical Properties

translucent crystals or white powder

Chemical Properties

Sodium thiosulfate occurs as odorless and colorless crystals, a crystalline powder or granules. It is efflorescent in dry air and deliquescent in moist air.

Uses

Titrimetry.

Uses

Sodium thiosulfate pentahydrate is used as an analytical reagent in laboratories. It is used in photographic processing and in gold extraction. Its alkylated derivatives, S-alkylthiosulfonates, are known as Bunte salts. It is involved in the preparation of thioglycolic acid. Furthermore, it is used to dechlorinate tap water, for removing free bromine from solutions and to check the pH of bleach solutions with liquid indicators. Other uses include tanning of leather; as an active component in hand warmers and chemical heating pads and as an anionic surfactant to aid in the dispersion of pharmaceutical preparations.

Definition

ChEBI: Sodium thiosulfate pentahydrate is a hydrate consisting of sodium thiosulfate with 5 mol eq. of water. It has a role as an antidote to cyanide poisoning, a nephroprotective agent and an antifungal drug. It contains a sodium thiosulfate.

Production Methods

On an industrial scale, sodium thiosulfate is produced chiefly from liquid waste products of sodium sulfide or sulfur dye manufacture. Small-scale synthesis is done by boiling an aqueous solution of sodium sulfite with sulfur.

brand name

Sulfactol (Sterling Winthrop).

Pharmaceutical Applications

Sodium thiosulfate is used as an antioxidant in pharmaceuticals (ophthalmic, intravenous, and oral preparations). It has also been used for its antifungal properties and as a reagent in analytical chemistry.

Safety

Sodium thiosulfate is used in ophthalmic, intravenous, and oral pharmaceutical preparations. Apart from osmotic disturbances, sodium thiosulfate is relatively nontoxic. It is moderately toxic by the subcutaneous route and mildly irritating to respiratory tract and skin. Large oral doses have a cathartic action.
LD50 (IP, mouse) 5.6 g/kg
LD50 (IV, mouse) 2.4 g/kg

storage

Sodium thiosulfate decomposes on heating. The bulk powder should be stored in a cool place, and the container should be kept tightly closed in a dry and well-ventilated place. It should not be stored near acids.

Purification Methods

Crystallise it from EtOH/H2O solutions or from water (0.3mL/g) below 60o by cooling to 0o, and dry it at 35o over P2O5 under vacuum. [Foerster & Mommsen Chem Ber 57 258 1924.] This salt is used as a secondary standard in volumetric analysis [Kilpatrick J Am Chem Soc 45 2132 1923], and is used as “Hypo” in photography [Hargreaves & Dunningham J Soc Chem Ind 42 147T 1923.]

Incompatibilities

Sodium thiosulfate is incompatible with iodine, with acids, and with lead, mercury, and silver salts. It may reduce the activity of some preservatives, including bronopol, phenylmercuric salts, and thimerosal.

Regulatory Status

GRAS listed. Included in the FDA Inactive Ingredients Database (IV solutions; ophthalmic solutions and suspensions; oral capsules, solutions, and tablets). Included in the Canadian List of Acceptable Non-medicinal Ingredients.

Sodium thiosulfate pentahydrate Preparation Products And Raw materials

Raw materials

ZINC Sulfur Calcium oxide Sodium sulfide Sodium sulfite Sulfur dioxide Sulphur Black 1 Industrial nitric acid Potassium sodium tartrate Vanadium(V) oxide Hydrochloric acid Sulphur Sodium hydroxide BARIUM SULFIDE Activated carbon Sulfuric acid Sodium carbonate

Preparation Products

(1S,2S,3R,5S)-(+)-2,3-Pinanediol 5-Bromo-2-hydroxymethylpyridine Molosultap 5-BROMO-2-METHYLPYRIDINE N-OXIDE Insecticide double agent 5-bromo-1H-indazole Sodium thiosulfate Chlorotrifluoroethylene Cartap 2-QUINOXALINECARBALDEHYDE 5-Bromopyridine-2-carbaldehyde Allicin S-METHYL-S-BENZYL SULFOXIMINE 2-(TRIFLUOROMETHYL)-4-ISOCYANATOPYRIDINE Bromoform Fomesafen
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View Lastest Price from Sodium thiosulfate pentahydrate manufacturers

HebeiShuoshengImportandExportco.,Ltd
Product
Sodium thiosulfate pentahydrate 10102-17-7
Price
US $6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000KG/Month
Release date
2024-08-14
HebeiShuoshengImportandExportco.,Ltd
Product
Sodium thiosulfate pentahydrate 10102-17-7
Price
US $6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000KG/Month
Release date
2024-08-14
Hebei Andu Technology Com.,Ltd
Product
Sodium thiosulfate pentahydrate 10102-17-7
Price
US $3.60/kg
Min. Order
1kg
Purity
≥99%
Supply Ability
3000tons/month
Release date
2024-07-30

10102-17-7, Sodium thiosulfate pentahydrateRelated Search:

Sodium acetate Sodium chloride Sodium bicarbonate Sodium sulfate DL-α-Tocopherol 5-Chlorovaleric acid 4-(Diethylamino)salicylaldehyde Diphenolic acid Pralmorelin Sodium hydroxide Diclofenac sodium Sodium thiosulfate Sodium benzoate Sodium thioglycolate Sodium thiocyanate PENTAMETHYLDISILOXANE Bismuth nitrate pentahydrate Sodium tetraborate decahydrate Sodium Thiosulfate Hydrate

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  • 16g
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