ChemicalBook > CAS DataBase List > Ethyl 2-aminopropanoate hydrochloride

Ethyl 2-aminopropanoate hydrochloride

Product Name
Ethyl 2-aminopropanoate hydrochloride
CAS No.
617-27-6
Chemical Name
Ethyl 2-aminopropanoate hydrochloride
Synonyms
NSC 46032;DL-Ala-OEt·HCl;H-DL-ALA-OET HCL;DL-ALANINE-OET HCL;TIMTEC-BB SBB004040;Ethyl alaninate HCL;DL-Alanine ethyl est;DL-ALA ETHYL ESTER HCL;H-DL-ALA-OET HYDROCHLORIDE;DL-Alanine Ethyl Ester HCl
CBNumber
CB8121073
Molecular Formula
C5H12ClNO2
Formula Weight
153.61
MOL File
617-27-6.mol
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Ethyl 2-aminopropanoate hydrochloride Property

Melting point:
85-87 °C(lit.)
storage temp. 
Inert atmosphere,2-8°C
solubility 
Methanol (Sparingly), Water
form 
Granular Powder and Granules
color 
White
Sensitive 
Hygroscopic
BRN 
3654425
InChI
InChI=1S/C5H11NO2.ClH/c1-3-8-5(7)4(2)6;/h4H,3,6H2,1-2H3;1H
InChIKey
JCXLZWMDXJFOOI-UHFFFAOYSA-N
SMILES
C(=O)(C(N)C)OCC.Cl
CAS DataBase Reference
617-27-6(CAS DataBase Reference)
EPA Substance Registry System
Alanine, ethyl ester, hydrochloride (617-27-6)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-24/25
WGK Germany 
3
TSCA 
Yes
HS Code 
29224999
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H226Flammable liquid and vapour

H304May be fatal if swallowed and enters airways

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P331Do NOT induce vomiting.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
05180
Product name
DL-Alanine ethyl ester hydrochloride
Purity
≥99.0% (AT)
Packaging
5g
Price
$55.7
Updated
2023/06/20
Sigma-Aldrich
Product number
05180
Product name
DL-Alanine ethyl ester hydrochloride
Purity
≥99.0% (AT)
Packaging
25g
Price
$118
Updated
2023/06/20
TRC
Product number
A510575
Product name
DL-Alanine ethyl ester hydrochloride
Packaging
5g
Price
$50
Updated
2021/12/16
Usbiological
Product number
237415
Product name
DL-Alanine ethyl ester hydrochloride 99+%
Packaging
25g
Price
$177
Updated
2021/12/16
Usbiological
Product number
260234
Product name
DL-Alanine ethyl ester hydrochloride
Packaging
50g
Price
$212
Updated
2021/12/16
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Ethyl 2-aminopropanoate hydrochloride Chemical Properties,Usage,Production

Chemical Properties

White Crystalline Solid

Uses

Alanine derivative

reaction suitability

reaction type: solution phase peptide synthesis

Synthesis

64-17-5

302-72-7

617-27-6

The general procedure for the synthesis of ethyl 2-aminopropionate hydrochloride from ethanol and DL-alanine was as follows: commercially available DL-alanine (5.00 g, 56.12 mmol) was dissolved in 150 mL of anhydrous ethanol, 5 mL of 37% concentrated hydrochloric acid was added, and the mixture was refluxed for 5 hours. After completion of the reaction, the solvent was removed by evaporation and the resulting colorless oily residue was vacuum dried to give the target product in 92% yield. The product was characterized by 1H NMR (CDCl3): δ 1.05 (t, 3H, J=7.07Hz, -OCH2CH3), 1.45 (d, 3H, J=7.25Hz, -CHCH3), 3.48 (q, 2H, J=7.07Hz, -OCH2CH3), and 4.02 ppm (q, 1H, J=7.25Hz, - CHCH3). High-resolution mass spectrometry (HRMS, ESI, 140 eV) analysis showed that the m/z [M+H+] calculated value for C5H12NO2 was 118.0868 and the measured value was 118.0794.

References

[1] Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1994, # 7, p. 1455 - 1462
[2] Dalton Transactions, 2008, # 13, p. 1689 - 1697
[3] Polyhedron, 2014, vol. 67, p. 520 - 528
[4] Scientia Pharmaceutica, 2001, vol. 69, # 4, p. 329 - 350
[5] Bioorganic and Medicinal Chemistry, 2009, vol. 17, # 6, p. 2336 - 2350

Ethyl 2-aminopropanoate hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Ethyl 2-aminopropanoate hydrochloride manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
Ethyl 2-aminopropanoate hydrochloride 617-27-6
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-10-13
Career Henan Chemical Co
Product
l 2-aminopropanoate hydrochloride 617-27-6
Price
US $7.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2018-12-24

617-27-6, Ethyl 2-aminopropanoate hydrochlorideRelated Search:


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  • DL-Alanine ethyl ester hydrochloride≥ 99% (Assay)
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  • 617-27-6
  • C5H11NO2HCl
  • Specialty Synthesis
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  • Amino Acid Derivatives
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  • Amino Acids 13C, 2H, 15N
  • Amino Acids & Derivatives
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