ASIALOGANGLIOSIDE-GM2
- Product Name
- ASIALOGANGLIOSIDE-GM2
- CAS No.
- 35960-33-9
- Chemical Name
- ASIALOGANGLIOSIDE-GM2
- Synonyms
- GG3;ASIALO GM2;Glycolipid GA2;GA2 GANGLIOSIDE;Ganglioside GA2;gangliosides (Gls);Tay-Sachs globoside;CERAMIDE TRIHEXOSIDE;ASIALOGANGLIOSIDE-GM2;Glycosphingolipid GA2
- CBNumber
- CB8124322
- Molecular Formula
- C56H104N2O18
- Formula Weight
- 1093.42756
- MOL File
- 35960-33-9.mol
ASIALOGANGLIOSIDE-GM2 Property
- storage temp.
- −20°C
- solubility
- Chloroform:Methanol:Water (2:1:0.1): Soluble
- form
- lyophilized powder
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- 24629
- Product name
- Ganglioside GM2 Asialo Mixture
- Purity
- ≥98%
- Packaging
- 100μg
- Price
- $765
- Updated
- 2024/03/01
- Product number
- G235075
- Product name
- GangliosideGM2,Asialo
- Packaging
- 100μg
- Price
- $180
- Updated
- 2021/12/16
- Product number
- G235075
- Product name
- GangliosideGM2,Asialo
- Packaging
- 250μg
- Price
- $365
- Updated
- 2021/12/16
- Product number
- 297086
- Product name
- GA2-Ganglioside
- Packaging
- 1mg
- Price
- $626
- Updated
- 2021/12/16
- Product number
- 5309EL
- Product name
- N-[(E,2R,3S)-1-[5-[5-[3-Acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-hydroxyoctadec-4-en-2-yl]octadecanamide
- Packaging
- 1mg
- Price
- $475
- Updated
- 2021/12/16
ASIALOGANGLIOSIDE-GM2 Chemical Properties,Usage,Production
Description
Ganglioside GM2 asialo (asialo- GM2) is a glycosphingolipid containing three monosaccharide residues and a fatty acid of variable chain length but lacking the sialic acid residue present on ganglioside M2. Asialo-GM2 levels are low-to-undetectable in normal human brain, but it accumulates in the brain of patients with Tay-Sachs and Sandhoff disease, which are neurodegenerative disorders characterized by deficiency of lysosomal β-hexosaminidase A and B, respectively. It also binds to various bacteria, including Pseudomonas isolates derived from cystic fibrosis patients. Asialo-GM2 mixture contains ganglioside GM2 asialo molecular species with fatty acyl chains of variable lengths. [Matreya, LLC. Catalog No. 1512]
Uses
Ganglioside GM2, Asialo is a semisynthetic ganglioside.
General Description
Gangliosides are major constituents of neuronal cell membranes and endoplasmic reticulum; contain a sialated polysaccharide chain linked to ceramide through a β-glycosidic linkage; for classification of gangliosides see Svennerholm, L., et al. (eds.), Structure and Function of Gangliosides, New York, Plenum, 1980.
Biochem/physiol Actions
Degraded form of Asialoganglioside-GM1 ganglioside.
ASIALOGANGLIOSIDE-GM2 Preparation Products And Raw materials
Raw materials
Preparation Products
ASIALOGANGLIOSIDE-GM2 Suppliers
- Tel
- --
- Fax
- --
- jaeger@biotrend.com
- Country
- Germany
- ProdList
- 6115
- Advantage
- 76