Arjunolic acid
- Product Name
- Arjunolic acid
- CAS No.
- 465-00-9
- Chemical Name
- Arjunolic acid
- Synonyms
- arjunolicaci;Arjulic acid;arjunolic acid;Arjunolic acid, 10 mM in DMSO;Arjunolic acid >=95% (LC/MS-ELSD);2,3,23-Trihydroxyolean-12-en-28-oic acid;Olean-12-en-28-oicacid, 2,3,23-trihydroxy-, (2a,3b,4a)-;(2alpha,3beta,4alpha)-2,3,23-Trihydroxy-olean-12-en-28-oic acid;hepatocyte injury,hyperglycemia,Inhibitor,type 1 diabetes,antimicrobial,antioxidant,Reactive Oxygen Species,Antidiabetic,Arjunolic acid,antibacterial,inhibit,Symplocos lancifolia,reactive oxygen
- CBNumber
- CB81366679
- Molecular Formula
- C30H48O5
- Formula Weight
- 488.7
- MOL File
- 465-00-9.mol
Arjunolic acid Property
- Melting point:
- 332-334 °C
- Boiling point:
- 606.0±55.0 °C(Predicted)
- Density
- 1.19±0.1 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- Powder
- pka
- 4.62±0.70(Predicted)
- color
- White to off-white
- InChIKey
- RWNHLTKFBKYDOJ-QBUVGUFVNA-N
- SMILES
- [C@@H]1(O)C[C@@]2([C@@]3([H])CC=C4[C@]5([C@](C(O)=O)(CCC(C)(C)C5)CC[C@@]4(C)[C@]3(C)CC[C@@]2([H])[C@](C)(CO)[C@H]1O)[H])C |&1:0,3,4,9,10,22,24,28,30,34,r|
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- SMB00119
- Product name
- Arjunolic acid
- Purity
- ≥95% (LC/MS-ELSD)
- Packaging
- 1mg
- Price
- $324
- Updated
- 2025/07/31
- Product number
- 29438
- Product name
- Arjunolic Acid
- Packaging
- 500μg
- Price
- $121
- Updated
- 2024/03/01
- Product number
- 29438
- Product name
- Arjunolic Acid
- Packaging
- 10mg
- Price
- $1201
- Updated
- 2024/03/01
- Product number
- 29438
- Product name
- Arjunolic Acid
- Packaging
- 1mg
- Price
- $230
- Updated
- 2024/03/01
- Product number
- 29438
- Product name
- Arjunolic Acid
- Packaging
- 5mg
- Price
- $662
- Updated
- 2024/03/01
Arjunolic acid Chemical Properties,Usage,Production
Description
Arjunolic acid is a triterpene that has been found in T. arjuna and has diverse biological activities, including antioxidant, anticancer, and anti-inflammatory properties. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals in a cell-free assay when used at a concentration of 0.8 mM. Arjunolic acid (20 mg/kg for four days) prevents arsenic-induced decreases in the activity of superoxide dismutase (SOD1), catalase, GST, and glutathione reductase in mouse brain. It reduces tumor growth in an Ehrlich murine spontaneous adenocarcinoma model when administered at doses of 100 and 250 mg/kg for 20 days. Arjunolic acid reduces renal fibrosis and increases in kidney TNF-α and IL-1β levels induced by cisplatin in mice when administered at doses of 100 and 250 mg/kg per day for 10 days.
Uses
Arjunolic Acid is a naturally occurring terpenoid which displays anti-inflammatory activity as well as protective effects during chemical induced organ pathophysiology.
Definition
ChEBI: A pentacyclic triterpenoid that is olean-12-en-28-oic acid substituted by hydroxy groups at positions 2, 3 and 23 (the 2alpha,3beta stereoisomer). Isolated from Symplocos lancifolia and Juglans sinensi , it exhibits antioxidant and antimicrobial activities.
References
[1] MAHUA SINHA Parames C S Prasenjit Manna. Protective effect of arjunolic acid against arsenic-induced oxidative stress in mouse brain.[J]. Journal of Biochemical and Molecular Toxicology, 2008, 22 1: 15-26. DOI: 10.1002/jbt.20209
[2] NEHAL M. ELSHERBINY Mohammed M H A G. Anti-tumor activity of arjunolic acid against Ehrlich Ascites Carcinoma cells in vivo and in vitro through blocking TGF-β type 1 receptor[J]. Biomedicine & Pharmacotherapy, 2016, 82: Pages 28-34. DOI: 10.1016/j.biopha.2016.04.046
[3] NEHAL M. ELSHERBINY Mohammed M H A G Mohamed A Eladl. Renal protective effects of arjunolic acid in a cisplatin-induced nephrotoxicity model[J]. Cytokine, 2016, 77: Pages 26-34. DOI: 10.1016/j.cyto.2015.10.010
Arjunolic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Arjunolic acid manufacturers
- Product
- Arjunolic acid 465-00-9
- Price
- US $8.00/KG
- Min. Order
- 1KG
- Purity
- >98% HPLC
- Supply Ability
- 20 tons
- Release date
- 2020-02-17