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3-Bromo-4-chloropyridine

Product Name
3-Bromo-4-chloropyridine
CAS No.
36953-42-1
Chemical Name
3-Bromo-4-chloropyridine
Synonyms
4-CHLORO-3-BROMOPYRIDINE;3-BROMO-4-CHLOROPYRIDINE;3-BroMo-4-chloridepyridine;Pyridine, 3-bromo-4-chloro-;3-Bromo-4-chloropyridine,98%;3-broMo -4-chlorine pyridine;3-BroMo-2-chloropyridine, 97+%;3-BroMo-4-chloropyridine, 98% 1GR;3-Bromo-4-chloropyridine ISO 9001:2015 REACH;TIANFUCHEM--36953-42-1--3-Bromo-4-chloropyridine in stock
CBNumber
CB8138363
Molecular Formula
C5H3BrClN
Formula Weight
192.44
MOL File
36953-42-1.mol
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3-Bromo-4-chloropyridine Property

Melting point:
17.5-18.5 °C
Boiling point:
115 °C(Press: 20 Torr)
Density 
1.19
refractive index 
1.453
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
form 
Liquid After Melting
pka
1.74±0.10(Predicted)
color 
Clear colorless to yellow
InChI
InChI=1S/C5H3BrClN/c6-4-3-8-2-1-5(4)7/h1-3H
InChIKey
QADXKWUCCGPQNR-UHFFFAOYSA-N
SMILES
C1=NC=CC(Cl)=C1Br
CAS DataBase Reference
36953-42-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn,Xi,T
Risk Statements 
36/37/38-20/22-41-37/38-25
Safety Statements 
36/37/39-26-22-45-39
HazardClass 
IRRITANT
HS Code 
29333990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
CDS003116
Product name
3-Bromo-4-chloropyridine
Purity
Aldrich<SUP>CPR</SUP>
Packaging
250 mg
Price
$73.1
Updated
2025/07/31
TRC
Product number
B684388
Product name
3-Bromo-4-chloropyridine
Packaging
100mg
Price
$45
Updated
2021/12/16
TRC
Product number
B684388
Product name
3-Bromo-4-chloropyridine
Packaging
500mg
Price
$65
Updated
2021/12/16
AK Scientific
Product number
N150
Product name
3-Bromo-4-chloropyridine
Packaging
5g
Price
$23
Updated
2021/12/16
Matrix Scientific
Product number
024993
Product name
3-Bromo-4-chloropyridine
Purity
98%
Packaging
5g
Price
$26
Updated
2021/12/16
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3-Bromo-4-chloropyridine Chemical Properties,Usage,Production

Chemical Properties

Light yellow needles

Uses

3-Bromo-4-chloropyridine can be used as a bulk drug intermediate in pharmaceutical synthesis.

Synthesis

31270-80-1

36953-42-1

220939-72-0

Example 543A Synthesis of 3-bromo-4-chlorofuro[3,2-c]pyridine: 4-Chlorofuro[3,2-c]pyridine (commercially available, 10.60 g, 69 mmol) was dissolved in carbon tetrachloride (135 mL) and cooled to -15°C. Bromine (12.13 g, 80 mmol) was added dropwise over 15 min. The reaction mixture was stirred at room temperature for 18 hours. Upon completion of the reaction, the solvent was removed under vacuum. The residue was dissolved in methanol (250 mL), 20% aqueous sodium hydroxide solution (35 mL) was added and stirring was continued for 1 hour at room temperature. Subsequently, methanol was removed under vacuum and the residue was partitioned between water (100 mL) and dichloromethane (50 mL). The organic layers were combined, dried over anhydrous magnesium sulfate, and the solvent was removed in vacuo to afford 3-bromo-4-chlorofuro[3,2-c]pyridine 15.45 g (96% yield) as a solid. Mass spectrum (ESI(+)) m/e 232,234 (M + H)+.

References

[1] Patent: US2005/26944, 2005, A1

3-Bromo-4-chloropyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 3-Bromo-4-chloropyridine manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
3-Bromo-4-chloropyridine 36953-42-1
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100 mt
Release date
2024-12-03
Henan Fengda Chemical Co., Ltd
Product
3-Bromo-2-chloropyridine 36953-42-1
Price
US $200.00-1.00/KG
Min. Order
1KG
Purity
99%, 99.5% Sublimated
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-30
Dideu Industries Group Limited
Product
3-Bromo-4-chloropyridine 36953-42-1
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons min
Release date
2021-09-03

36953-42-1, 3-Bromo-4-chloropyridineRelated Search:


  • 3-BROMO-4-CHLOROPYRIDINE
  • 4-CHLORO-3-BROMOPYRIDINE
  • 3-BroMo-4-chloropyridine, 98% 1GR
  • 3-BroMo-4-chloridepyridine
  • 3-Bromo-4-chloropyridine,98%
  • 3-BroMo-2-chloropyridine, 97+%
  • 3-broMo -4-chlorine pyridine
  • Pyridine, 3-bromo-4-chloro-
  • 3-Bromo-4-chloropyridine ISO 9001:2015 REACH
  • TIANFUCHEM--36953-42-1--3-Bromo-4-chloropyridine in stock
  • 36953-42-1
  • 624-28-7
  • Pyridine
  • Pyridine series
  • Halides
  • Pyridines