ChemicalBook > CAS DataBase List > 2-Bromo-3-methylthiophene
2-Bromo-3-methylthiophene
- Product Name
- 2-Bromo-3-methylthiophene
- CAS No.
- 14282-76-9
- Chemical Name
- 2-Bromo-3-methylthiophene
- Synonyms
- 2B3MT;178.04;TH1-Br;2-Bromo-3-methylthio;2-bromo-3-methyltiophene;3-Methyl-2-bromothiophene;2-BROMO-3-METHYLTHIOPHENE;Thiophene,2-bromo-3-methyl-;2-Bromo-3-methylthiophene>2-Bromo-3-methylthiophene 97%
- CBNumber
- CB8147031
- Molecular Formula
- C5H5BrS
- Formula Weight
- 177.06
- MOL File
- 14282-76-9.mol
More
Less
2-Bromo-3-methylthiophene Property
- Melting point:
- <25 °C
- Boiling point:
- 173-176 °C (lit.)
- Density
- 1.572 g/mL at 25 °C (lit.)
- refractive index
- n20/D 1.572(lit.)
- Flash point:
- 155 °F
- storage temp.
- 2-8°C
- Water Solubility
- Insoluble in water
- solubility
- soluble in Chloroform, Ethyl Acetate
- form
- liquid
- color
- Pale yellow
- Specific Gravity
- 1.580
- BRN
- 105719
- CAS DataBase Reference
- 14282-76-9(CAS DataBase Reference)
- NIST Chemistry Reference
- Thiophene, 2-bromo-3-methyl-(14282-76-9)
More
Less
Safety
- Hazard Codes
- T,Xi,Xn
- Risk Statements
- 25-41-43-36/37/38-20/21/22
- Safety Statements
- 26-36/37/39-45
- RIDADR
- UN 2810
- WGK Germany
- 3
- Hazard Note
- Harmful
- HazardClass
- IRRITANT-HARMFUL, KEEP COLD
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 29349990
More
Less
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H318Causes serious eye damage
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
More
Less
N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 337021
- Product name
- 2-Bromo-3-methylthiophene
- Purity
- 95%
- Packaging
- 1g
- Price
- $26.4
- Updated
- 2023/06/20
Sigma-Aldrich
- Product number
- 337021
- Product name
- 2-Bromo-3-methylthiophene
- Purity
- 95%
- Packaging
- 5g
- Price
- $71.7
- Updated
- 2023/06/20
TCI Chemical
- Product number
- B1025
- Product name
- 2-Bromo-3-methylthiophene
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $44
- Updated
- 2024/03/01
TCI Chemical
- Product number
- B1025
- Product name
- 2-Bromo-3-methylthiophene
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $129
- Updated
- 2024/03/01
Alfa Aesar
- Product number
- L11393
- Product name
- 2-Bromo-3-methylthiophene, 97%
- Packaging
- 5g
- Price
- $53.65
- Updated
- 2024/03/01
More
Less
2-Bromo-3-methylthiophene Chemical Properties,Usage,Production
Chemical Properties
clear colorless to light yellow liquid
Uses
2-Bromo-3-methylthiophene was used in the preparation of poly(3,3′′′-dimethyl-(2,2′:5′,2′:5′,2′′′)tetrathiophene)). It was also used in the preparation of 2-bromo-3-(bromomethyl)thiophene, lachrymatory compound.
Application
2-Bromo-3-methylthiophene is used as a pharmaceutical intermediate. It is used to prepare pyrazolo[3,4-d]pyrimidine derivatives as inhibitors of human enterovirus, coxsackievirus, echovirus, influenza virus, herpes simplex virus and rhinovirus. It is also used in the synthesis of oral α7 nicotinic receptor agonists.
Preparation
2-Bromo-3-methylthiophene synthesis: To a solution of glacial AcOH (100 mL), acetic anhydride (4.0 g, 0.039 mol), and 3-methylthiophene (9.82 g, 0.100 mol) as a stirred mixture was added NBS (19.6 g, 0.11 mol) in one portion with a slight exotherm to 44 oC. After 20 min the reaction mixture was poured onto ice, neutralized with sodium bisulfite and extracted with ether. The ether layer was washed with water and concentrated to give 11.3 g (64%) of 2-bromo-3-methylthiophene as a tan colored liquid in 88% purity by GC area % analysis: 1H NMR (CDCl3) d 7.1 (d, 1H, J=5.7 Hz), 6.7 (d, 1H, J=5.9 Hz), 2.2 (s, 3H).
General Description
2-Bromo-3-methylthiophene is formed (approx. 90%) by bromination of 3-methyl thiophene with N-bromosuccinimide in the absence of benzoyl peroxide.
2-Bromo-3-methylthiophene Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
2-Bromo-3-methylthiophene Suppliers
- Tel
- 0371-63315541 13323832564
- Fax
- QQ:3001332135
- 3001332135@qq.com
- Country
- China
- ProdList
- 9880
- Advantage
- 58
- Tel
- 0515-82159088 13770142076
- Fax
- 86-0515-8215909
- twl@njuchem.com
- Country
- China
- ProdList
- 213
- Advantage
- 65
- Tel
- 0393-0393-0393-8910800 15238090375
- Fax
- 0393-8912775
- info@huichengchem.com
- Country
- China
- ProdList
- 557
- Advantage
- 64
- Tel
- 15250805028
- Fax
- QQ：1048979734
- 1048979734@qq.com
- Country
- China
- ProdList
- 304
- Advantage
- 58
- Tel
- 18678041314 18765609661
- 2547772582@qq.com
- Country
- China
- ProdList
- 877
- Advantage
- 58
- Tel
- 021-50182298 021-50180596
- Fax
- +86-21-57758967
- sales@boylechem.com
- Country
- China
- ProdList
- 2208
- Advantage
- 55
- Tel
- 010-82848833 400-666-7788
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 021-61259108 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- 400-0066400 13621662912
- Fax
- 021-55660885
- sales@jonln.com
- Country
- China
- ProdList
- 1995
- Advantage
- 65
- Tel
- 400-6106006
- Fax
- 021-67582001/03/05
- saleschina@alfa-asia.com
- Country
- China
- ProdList
- 30123
- Advantage
- 84
- Tel
- 021-67121386
- Fax
- 021-67121385
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 24529
- Advantage
- 81
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44689
- Advantage
- 61
- Tel
- +86 (0) 571 85 58 67 18
- Fax
- 0086-571-85864795
- sales@capotchem.com
- Country
- China
- ProdList
- 18207
- Advantage
- 66
- Tel
- 010-82967028 13552068683
- Fax
- +86-10-82967029
- 2355560935@qq.com
- Country
- China
- ProdList
- 12390
- Advantage
- 60
- Tel
- 0573-85285100 18627885956
- Fax
- 0573-85285100
- isenchem@163.com
- Country
- China
- ProdList
- 9413
- Advantage
- 66
- Tel
- 13526569071
- sales@leadmedpharm.com
- Country
- China
- ProdList
- 7905
- Advantage
- 64
- Tel
- 400-6009262 16621234537
- Fax
- 021-64823266
- chenyj@titansci.com
- Country
- China
- ProdList
- 14103
- Advantage
- 59
- Tel
- 021-50795510 4000665055
- Fax
- 021-50795055
- sales@accelachem.com
- Country
- China
- ProdList
- 11655
- Advantage
- 64
- Tel
- 021-58099652-8005 13585536065
- Fax
- 021-58099609
- bin.wu@shlschem.com
- Country
- China
- ProdList
- 9809
- Advantage
- 59
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
- ProdList
- 42958
- Advantage
- 64
- Tel
- 86-0571-85151182
- Fax
- 86-0571-85151182
- Country
- China
- ProdList
- 5691
- Advantage
- 66
- Tel
- 15527768850
- 1791901229@qq.com
- Country
- China
- ProdList
- 8843
- Advantage
- 52
- Tel
- 010-82954736 13391601435
- sales@isomersyn.com
- Country
- China
- ProdList
- 3295
- Advantage
- 57
- Tel
- 400-1166-196 18981987031
- Fax
- 028-84555506 800101999
- cdhxsj@163.com
- Country
- China
- ProdList
- 11707
- Advantage
- 57
- Tel
- 400 638 7771
- sales@heowns.com
- Country
- China
- ProdList
- 14435
- Advantage
- 57
- Tel
- 027-85736489
- Fax
- 86-27-85736485
- info@kemiworks.net
- Country
- China
- ProdList
- 540
- Advantage
- 57
- Tel
- 0086-755-86198205
- acinfo@aemonchem.com
- Country
- China
- ProdList
- 1931
- Advantage
- 57
- Tel
- 0571-82693216
- Fax
- +86-571-82880190
- info@yuhaochemical.com
- Country
- China
- ProdList
- 9387
- Advantage
- 52
- Tel
- 0370-2785118 17550508557
- Fax
- QQ：3470079902
- 675141927@qq.com
- Country
- China
- ProdList
- 3203
- Advantage
- 55
- Tel
- 4008-755-333 18080918076
- Fax
- 028-86757656
- 800078821@qq.com
- Country
- China
- ProdList
- 9718
- Advantage
- 55
- Tel
- 021-61551611 13296011611
- Fax
- ＋86 21-50676805
- contact@trustwe.com
- Country
- China
- ProdList
- 9895
- Advantage
- 58
- Tel
- 86-21-34053660
- Fax
- 86-21-34053661
- sale@labgogo.com
- Country
- China
- ProdList
- 9865
- Advantage
- 52
- Tel
- +86-21-60341587
- Fax
- +86-21-61294319
- sales@topbiochem.com
- Country
- China
- ProdList
- 6175
- Advantage
- 58
- Tel
- 13901585132
- Fax
- +86-25-52131256
- 799750417@qq.com
- Country
- China
- ProdList
- 8878
- Advantage
- 55
- Tel
- 18017383231 18017383231
- Fax
- qq：2817624287
- lyh_antaeus@163.com
- Country
- China
- ProdList
- 9347
- Advantage
- 55
- Tel
- 4009209199
- Fax
- 86-021-52271987
- sales@9dingchem.com
- Country
- China
- ProdList
- 18209
- Advantage
- 56
- Tel
- 400-400-6206333 18521732826
- Fax
- 021-50323701
- market@aladdin-e.com
- Country
- China
- ProdList
- 25003
- Advantage
- 65
- Tel
- 021-61552785
- Fax
- 021-55660885
- sales@shshiji.com
- Country
- China
- ProdList
- 9545
- Advantage
- 55
- Tel
- 86-0755-86635001
- Fax
- 86-0755-22642228
- cantotech@126.com
- Country
- China
- ProdList
- 4566
- Advantage
- 55
- Tel
- 021-62960152
- Fax
- 021-52212593
- 934678158@qq.com
- Country
- China
- ProdList
- 9899
- Advantage
- 55
- Tel
- +86-021-50935922
- Fax
- +86-021-33847795
- Country
- China
- ProdList
- 7865
- Advantage
- 55
- Tel
- +86-28-85122536 85324413
- Fax
- +86-28-85326443
- market@astatech.cn
- Country
- China
- ProdList
- 8026
- Advantage
- 55
- Tel
- 0570-3066667
- Fax
- 0570-3063388
- Country
- China
- ProdList
- 3930
- Advantage
- 58
- Tel
- 400-8706899
- Fax
- 400-8706899
- hysj_bj.com
- Country
- China
- ProdList
- 3583
- Advantage
- 55
- Tel
- 13971561712, 13995564702, 027-50664929
- Fax
- 027-50664927
- hbeixys2001@163.com
- Country
- China
- ProdList
- 3120
- Advantage
- 55
- Tel
- 021-60549325 18616193163
- Fax
- 021-33250306
- Country
- China
- ProdList
- 4526
- Advantage
- 56
- Tel
- 400-0066400 13621662912
- Fax
- 021-55660885
- 422131432@qq.com
- Country
- China
- ProdList
- 9978
- Advantage
- 55
- Tel
- 0554-2106669
- Fax
- 0554-2666215
- sales1@kedichem.com
- Country
- China
- ProdList
- 4924
- Advantage
- 55
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 41462
- Advantage
- 60
- Tel
- 0371-53732842 15981811963
- Fax
- 0371-86239377
- 1758257485@qq.com
- Country
- China
- ProdList
- 950
- Advantage
- 56
More
Less
View Lastest Price from 2-Bromo-3-methylthiophene manufacturers
Shaanxi Dideu Medichem Co. Ltd
- Product
- 2-Bromo-3-methylthiophene 14282-76-9
- Price
- US $1.00-1.00/KG
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 50tons
- Release date
- 2020-04-22
Hebei Weibang Biotechnology Co., Ltd
- Product
- 2-Bromo-3-methylthiophene 14282-76-9
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-10-31
Hebei Yanxi Chemical Co., Ltd.
- Product
- 2-Bromo-3-methylthiophene 14282-76-9
- Price
- US $10.00-1.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 20 tons
- Release date
- 2023-10-08
14282-76-9, 2-Bromo-3-methylthiopheneRelated Search:
4-Bromomethylbenzoic acid
3-Methylthiophene
(Bromomethyl)cyclopropane
Bromotrimethylsilane
Poly(3-hexylthiophene-2,5-diyl)
2-Bromothiophene
Methyl bromide
Bromine
2-BROMO-5-CHLORO-3-METHYLBENZO[B]THIOPHENE
2,3,5-TRIBROMO-4-METHYLTHIOPHENE
2,5-DIBROMO-3-DECYLTHIOPHENE
2,5-Dibromo-3-hexylthiophene
2,5-Dibromo-3-octylthiophene
2,5-DIBROMO-3-METHYLTHIOPHENE
2,5-DIBROMO-3-DODECYLTHIOPHENE
2,5-DIBROMO-3-BUTYLTHIOPHENE
2-Bromo-3-bromomethylthiophene
3-bromo-2-methylthiophene