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Acrichin dihydrochloride

Product Name
Acrichin dihydrochloride
CAS No.
69-44-3
Chemical Name
Acrichin dihydrochloride
Synonyms
AMODIAQUINE HCL;camoquinhydrochloride;Amodiaquine HCL USP31;AMODIAQUIN HYDROCHLORIDE;Acrichin dihydrochloride;Amodiquine hydrochloride;AMODIAQUINE HYDROCHLORIDE;AMODIAQUIN DIHYDROCHLORIDE;AMODIAQUINE DIHYDROCHLORIDE;BULK DRUG : AMODIAQUINE HYDROCHLORIDE (DMF GRADE)
CBNumber
CB8156037
Molecular Formula
C20H23Cl2N3O
Formula Weight
392.32
MOL File
69-44-3.mol
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Acrichin dihydrochloride Property

storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO: 125 mg/mL (291.52 mM)
form 
Solid
color 
Light yellow to yellow
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
C429303
Product name
4-((7-Chloroquinolin-4-yl)amino)-2-((diethylamino)methyl)phenolDihydrochloride
Packaging
10mg
Price
$45
Updated
2021/12/16
Matrix Scientific
Product number
099311
Product name
4-((7-Chloroquinolin-4-yl)amino)-2-((diethylamino)-methyl)phenol dihydrochloride
Purity
95+%
Packaging
10g
Price
$10
Updated
2021/12/16
Matrix Scientific
Product number
099311
Product name
4-((7-Chloroquinolin-4-yl)amino)-2-((diethylamino)-methyl)phenol dihydrochloride
Purity
95+%
Packaging
25g
Price
$19
Updated
2021/12/16
AK Scientific
Product number
N752
Product name
Amodiaquinedihydrochloride
Packaging
25g
Price
$25
Updated
2021/12/16
ApexBio Technology
Product number
C7157
Product name
Amodiaquine hydrochloride
Packaging
100mg
Price
$50
Updated
2021/12/16
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Acrichin dihydrochloride Chemical Properties,Usage,Production

Chemical Properties

Yellow crystalline solid; odorless; bitter. Soluble in water; sparingly soluble in alcohol; very slightly soluble in benzene, chloroform, and ether.

Originator

Camoquin HCl,Parke Davis,US,1950

Uses

Medicine (antimalarial).

Manufacturing Process

72.8 g (0.5 mol) of p-aminophenol hydrochloride is dissolved in 500 cc of water and added to 99 g (0.5 mol) of 4,7-dichloroquinoline. After a few minutes of warming in a steam bath, 4-(4'-hydroxyanilino)-7-chloroquinoline hydrochloride, of sufficient purity for use in further experiments, precipitates as a yellow crystalline solid. Recrystallized from methanol, the MP is over 300°C.
A mixture consisting of 13.5 g of 4-(4'-hydroxyanilino)-7-chloroquinoline hydrochloride dissolved in absolute ethanol is treated with a solution of 4.38 g of diethylamine and 1.8 g of paraformaldehyde in 20 cc of absolute ethanol. The reaction mixture is heated under reflux for 16 hours, evaporated to onehalf volume and the warm solution treated with an excess of hydrogen chloride dissolved in absolute ethanol. Acetone is added to the warm solution until it becomes turbid and then the solution is cooled. The crude dihydrochloride which separates is collected and purified by recrystallization from methanol; MP 240-242°C.
By using an equivalent amount of 4-(4'-hydroxyanilino)-7-bromoquinoline in the above procedure, 4-(3'-diethylaminomethyl-4'-hydroxyanilino)-7- bromoquinoline dihydrochloride is obtained; MP (base) 206-208°C dec.

brand name

Camoquin (Parke-Davis).

Therapeutic Function

Antimalarial

Acrichin dihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Acrichin dihydrochloride Suppliers

XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8843
Advantage
52
Hangzhou Yuhao Chemical Technology Co., Ltd
Tel
0571-82693216
Fax
+86-571-82880190
Email
info@yuhaochemical.com
Country
China
ProdList
9387
Advantage
52
Wuhan Fortuna Chemical Co., Ltd
Tel
027-59207852 13308628970
Fax
QQ3130921841
Email
buy@fortunachem.com
Country
China
ProdList
2876
Advantage
58
ShangHai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847 13636370518
Fax
021-55068248
Email
shyysw007@163.com
Country
China
ProdList
4940
Advantage
60
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12335
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66099280 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19915
Advantage
55
Shanghai Jian Chao Chemical Technology Co., Ltd.
Tel
18017383231 18017383231
Fax
qq:2817624287
Email
lyh_antaeus@163.com
Country
China
ProdList
9347
Advantage
55
Wuhan DKY Technology Co.,Ltd.
Tel
27-81302488 18007166089
Fax
027-81302088
Email
info@dkybpc.com
Country
China
ProdList
2024
Advantage
58
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41462
Advantage
60
Wuhan Dahua Pharmaceutical Co., Ltd.
Tel
027-59262863 13277907145 3091977954
Fax
027-59420980
Country
China
ProdList
4943
Advantage
58
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View Lastest Price from Acrichin dihydrochloride manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Acrichin dihydrochloride 69-44-3
Price
US $0.00/Kg/Drum
Min. Order
25KG
Purity
97%-103%; USP
Supply Ability
500kg
Release date
2021-08-20
.GZ HONESTCHEM CO.,LTD
Product
Acrichin dihydrochloride 69-44-3
Price
US $1.00/g
Min. Order
300g
Purity
99.8%
Supply Ability
20 TONS
Release date
2021-07-05
Anhui Ruihan Technology Co., Ltd
Product
Acrichin dihydrochloride 69-44-3
Price
US $30.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000t/year
Release date
2023-09-07

69-44-3, Acrichin dihydrochlorideRelated Search:


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  • 69-44-3
  • C20H24Cl3N3O
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