Acrichin dihydrochloride
- Product Name
- Acrichin dihydrochloride
- CAS No.
- 69-44-3
- Chemical Name
- Acrichin dihydrochloride
- Synonyms
- AMODIAQUINE HCL;camoquinhydrochloride;Amodiaquine HCL USP31;AMODIAQUIN HYDROCHLORIDE;Acrichin dihydrochloride;Amodiquine hydrochloride;AMODIAQUINE HYDROCHLORIDE;AMODIAQUIN DIHYDROCHLORIDE;AMODIAQUINE DIHYDROCHLORIDE;BULK DRUG : AMODIAQUINE HYDROCHLORIDE (DMF GRADE)
- CBNumber
- CB8156037
- Molecular Formula
- C20H23Cl2N3O
- Formula Weight
- 392.32
- MOL File
- 69-44-3.mol
Acrichin dihydrochloride Property
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO: 125 mg/mL (291.52 mM)
Safety
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330Rinse mouth.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- C429303
- Product name
- 4-((7-Chloroquinolin-4-yl)amino)-2-((diethylamino)methyl)phenolDihydrochloride
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- C7157
- Product name
- Amodiaquine hydrochloride
- Packaging
- 100mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- CS-0013341
- Product name
- Amodiaquine(dihydrochloride)
- Purity
- ≥98.0%
- Packaging
- 100mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- 099311
- Product name
- 4-((7-Chloroquinolin-4-yl)amino)-2-((diethylamino)-methyl)phenol dihydrochloride
- Purity
- 95+%
- Packaging
- 10g
- Price
- $10
- Updated
- 2021/12/16
- Product number
- C7157
- Product name
- Amodiaquine hydrochloride
- Packaging
- 200mg
- Price
- $80
- Updated
- 2021/12/16
Acrichin dihydrochloride Chemical Properties,Usage,Production
Chemical Properties
Yellow crystalline solid; odorless; bitter. Soluble in water; sparingly soluble in alcohol; very slightly soluble in benzene, chloroform, and ether.
Originator
Camoquin HCl,Parke Davis,US,1950
Uses
Medicine (antimalarial).
Manufacturing Process
72.8 g (0.5 mol) of p-aminophenol hydrochloride is dissolved in 500 cc of
water and added to 99 g (0.5 mol) of 4,7-dichloroquinoline. After a few
minutes of warming in a steam bath, 4-(4'-hydroxyanilino)-7-chloroquinoline
hydrochloride, of sufficient purity for use in further experiments, precipitates
as a yellow crystalline solid. Recrystallized from methanol, the MP is over
300°C.
A mixture consisting of 13.5 g of 4-(4'-hydroxyanilino)-7-chloroquinoline
hydrochloride dissolved in absolute ethanol is treated with a solution of 4.38 g of diethylamine and 1.8 g of paraformaldehyde in 20 cc of absolute ethanol.
The reaction mixture is heated under reflux for 16 hours, evaporated to onehalf
volume and the warm solution treated with an excess of hydrogen
chloride dissolved in absolute ethanol. Acetone is added to the warm solution
until it becomes turbid and then the solution is cooled. The crude
dihydrochloride which separates is collected and purified by recrystallization
from methanol; MP 240-242°C.
By using an equivalent amount of 4-(4'-hydroxyanilino)-7-bromoquinoline in
the above procedure, 4-(3'-diethylaminomethyl-4'-hydroxyanilino)-7-
bromoquinoline dihydrochloride is obtained; MP (base) 206-208°C dec.
brand name
Camoquin (Parke-Davis).
Therapeutic Function
Antimalarial
Acrichin dihydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Acrichin dihydrochloride Suppliers
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View Lastest Price from Acrichin dihydrochloride manufacturers
- Product
- Acrichin dihydrochloride 69-44-3
- Price
- US $0.00/Kg/Drum
- Min. Order
- 25KG
- Purity
- 97%-103%; USP
- Supply Ability
- 500kg
- Release date
- 2021-08-20
- Product
- Acrichin dihydrochloride 69-44-3
- Price
- US $30.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 1000t/year
- Release date
- 2023-09-07
- Product
- Acrichin dihydrochloride 69-44-3
- Price
- US $1.00/Kg
- Min. Order
- 1KG
- Purity
- 99.99%
- Supply Ability
- 500 Metric Ton/Day
- Release date
- 2021-03-01