5-METHOXY-2-METHYLINDOLE

Product Name: 5-METHOXY-2-METHYLINDOLE
CAS No.: 1076-74-0
Chemical Name: 5-METHOXY-2-METHYLINDOLE
Synonyms: NSC 63817;AKOS JY2082626;5-Methoxy-2-methyindole;2-Methyl-5-Methoxyindole;5-METHOXY-2-METHYLINDOLE;Indole, 5-methoxy-2-methyl-;5-Methoxy-2-methylindole>5-Methoxy-2-methylindole 99%;1H-Indole, 5-methoxy-2-methyl-;5-Methoxy-2-methylindole, 99+%
CBNumber: CB8174569
Molecular Formula: C10H11NO
Formula Weight: 161.2
MOL File: 1076-74-0.mol

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5-METHOXY-2-METHYLINDOLE Property

Melting point:: 86-88 °C (lit.)
Boiling point:: 145 °C / 1.5mmHg
Density: 1.0840 (rough estimate)
refractive index: 1.5200 (estimate)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Soluble in methanol (very faint turbidity.)
form: Crystalline Powder or Crystals
pka: 17.28±0.30(Predicted)
color: White to light beige
InChIKey: VSWGLJOQFUMFOQ-UHFFFAOYSA-N
CAS DataBase Reference: 1076-74-0(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 37/39-26
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: M15451
Product name: 5-Methoxy-2-methylindole
Purity: 99%
Packaging: 1g
Price: $52.4
Updated: 2024/03/01

Sigma-Aldrich

Product number: M15451
Product name: 5-Methoxy-2-methylindole
Purity: 99%
Packaging: 5g
Price: $174
Updated: 2024/03/01

TCI Chemical

Product number: M0730
Product name: 5-Methoxy-2-methylindole
Purity: >99.0%(GC)
Packaging: 1g
Price: $147
Updated: 2024/03/01

TCI Chemical

Product number: M0730
Product name: 5-Methoxy-2-methylindole
Purity: >99.0%(GC)
Packaging: 5g
Price: $584
Updated: 2024/03/01

Alfa Aesar

Product number: B21348
Product name: 5-Methoxy-2-methylindole, 99+%
Packaging: 1g
Price: $31.65
Updated: 2024/03/01

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5-METHOXY-2-METHYLINDOLE Chemical Properties,Usage,Production

Description

5-methoxy-2-methylindole is a useful organic raw material. It can be used as the reactant in the preparation of indolylquinoxalines by condensation reactions, in preparation of alkylindoles via Ir-catalyzed reductive alkylation, in arylation reactions in the presence of a palladium acetate catalyst, in enantioselective Friedel-Crafts alkylation, as well as in stereo selective synthesis of cyclopentaindolones via stereoselective [3+2] cyclopentannulation. It is also employed in inhibiting the chlorinating activity of myeloperoxidase (MPO) and in the metabolic synthesis of acrylacetic acid anti-inflammatory synthesis.

Chemical Properties

white to light beige crystalline powder or

Uses

An indole derivative shown to be an effective inhibitor of the chlorinating activity of myeloperoxidase (MPO). Used in the metabolic synthesis of arylacetic acid antiinflammatory synthesis.

Uses

reactant in preparation of indolylquinoxalines by condensation reactions1reactant in preparation of alkylindoles via Ir-catalyzed reductive alkylation2reactant in arylation reactions using a palladium acetate catalyst3reactant in enantioselective Friedel-Crafts alkylation4reactant in stereoselective synthesis of cyclopentaindolones via stereoselective [3+2] cyclopentannulation5

Uses

It is employed as a reactant in preparation of indolylquinoxalines by condensation reactions, reactant in preparation of alkylindoles via Ir-catalyzed reductive alkylation, reactant in arylation reactions using a palladium acetate catalyst, reactant in enantioselective Friedel-Crafts alkylation and reactant in stereoselective synthesis of cyclopentaindolones via stereoselective [3+2] cyclopentannulation. As an indole derivative shown to be an effective inhibitor of the chlorinating activity of myeloperoxidase (MPO). Used in the metabolic synthesis of arylacetic acid anti-inflammatory synthesis.

Definition

ChEBI: 5-Methoxy-2-methyl-1H-indole is a member of indoles.

References

https://www.alfa.com/en/catalog/B21348/
http://www.sigmaaldrich.com/catalog/product/aldrich/m15451?lang=en&region=US
https://pubchem.ncbi.nlm.nih.gov/compound/5-Methoxy-2-methylindole#section=2D-Structure

5-METHOXY-2-METHYLINDOLE Preparation Products And Raw materials

Raw materials

Acetone Zinc chloride Sodium bicarbonate 4-Methoxyphenylhydrazine hydrochloride

Preparation Products

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5-METHOXY-2-METHYLINDOLE Suppliers

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View Lastest Price from 5-METHOXY-2-METHYLINDOLE manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 5-METHOXY-2-METHYLINDOLE 1076-74-0
Price: US $0.10/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10
Release date: 2024-07-07

Henan Aochuang Chemical Co.,Ltd.

Product: 5-Methoxy-2-methylindole 1076-74-0
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-19

Nanjing jinheyou Trading Co., Ltd.

Product: 5-METHOXY-2-METHYLINDOLE 1076-74-0
Price: US $0.00/g
Min. Order: 1g
Purity: 95%min
Supply Ability: 20kg/month
Release date: 2019-12-20

1076-74-0, 5-METHOXY-2-METHYLINDOLERelated Search:

6-METHOXY-1,2,3,4-TETRAHYDRO-9 H-PYRIDO[3,4-B]INDOLE HYDROCHLORIDE 6-Methoxyharmalan 5-BENZYLOXYINDOLE-2-CARBOXYLIC ACID Indometacin ETHYL 5-BENZYLOXYINDOLE-2-CARBOXYLATE ETHYL 5-METHOXYINDOLE-2-CARBOXYLATE ETHYL 5,6-DIMETHOXYINDOLE-2-CARBOXYLATE 5-METHOXYINDOLE-2-CARBOXYLIC ACID 5-METHOXY-2-METHYLINDOLE 6-METHOXY-1,2,3,4-TETRAHYDRO-BETA-CARBOLINE 5-METHOXY-2-METHYLINDOLE-3-ACETIC ACID 5,6-DIMETHOXYINDOLE-2-CARBOXYLIC ACID 1-[P-CHLOROBENZOYL]-5-METHOXY-2-METHYLINDOLE-3-ACETIC ACID CARBOXYMETHYL ESTER 5-METHOXY-4-METHYLINDOLE 4-methoxy-2-methyl-1H-indole 5-METHOXY-1-METHYLINDOLE-3-CARBOXALDEHYDE,3-Formyl-5-methoxy-1-methylindole 4-METHOXY-1-METHYLINDOLE 2-Methylindole

5-Methoxy-2-methylindole, 99+%

5-METHOXY-2-METHYLINDOLE

AKOS JY2082626

5-Methoxy-2-methyindole

Indole, 5-methoxy-2-methyl-

5-Methoxy-2-Methylindole, 99+% 25GR

5-Methoxy-2-Methylindole, 99+% 5GR

2-Methyl-5-Methoxyindole

NSC 63817

5-Methoxy-2-methylindole 99%

1H-Indole, 5-methoxy-2-methyl-

5-Methoxy-2-methylindole&gt

5-Methoxy-2-methylindole, 99%, for synthesis

1076-74-0

Heterocyclic Building Blocks

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