2-Methoxy-3-(trifluoromethyl)pyridine

storage Uses

Product Name: 2-Methoxy-3-(trifluoromethyl)pyridine
CAS No.: 121643-44-5
Chemical Name: 2-Methoxy-3-(trifluoromethyl)pyridine
Synonyms: BUTTPARK 45\01-90;METHOXY-3-TRIFLUOROMETHYLPYRIDINE;2-Bromo-7-(trifluoromethyl)pyridine;2-METHOXY-3-(TRIFLUOROMETHYL)PYRIDINE;3-(trifluoroMethyl)-2-Methoxypyridine;2-Methoxy-3-(trifluoromethyl)pyridine>2-Methoxy-3-(trifluoromethyl)pyridine98%;2-Methoxy-3-(trifluoromethyl)pyridine 98%;2-Methoxy-3-(trifluoromethyl)pyridine ISO 9001：2015 REACH
CBNumber: CB8181415
Molecular Formula: C7H6F3NO
Formula Weight: 177.12
MOL File: 121643-44-5.mol

More

Less

2-Methoxy-3-(trifluoromethyl)pyridine Property

Boiling point:: 44 °C
Density: 1.297 g/mL at 25 °C
refractive index: n20/D 1.441
Flash point:: 118 °F
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: soluble in Methanol
form: clear liquid
pka: 0.97±0.10(Predicted)
color: Colorless to Almost colorless
InChI: InChI=1S/C7H6F3NO/c1-12-6-5(7(8,9)10)3-2-4-11-6/h2-4H,1H3
InChIKey: SSAZZVQVJJXPMB-UHFFFAOYSA-N
SMILES: C1(OC)=NC=CC=C1C(F)(F)F
CAS DataBase Reference: 121643-44-5(CAS DataBase Reference)

More

Less

Safety

Hazard Codes: T,Xi,Xn
Risk Statements: 10-25-36/37/38-20/21/22
Safety Statements: 16-26-45-36
RIDADR: UN 1992 3/PG 3
WGK Germany: 3
HazardClass: IRRITANT
PackingGroup: III
HS Code: 2933399990

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H226Flammable liquid and vapour

H300Fatal if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 658359
Product name: 2-Methoxy-3-(trifluoromethyl)pyridine
Purity: 96%
Packaging: 5g
Price: $86.1
Updated: 2023/06/20

TCI Chemical

Product number: M2191
Product name: 2-Methoxy-3-(trifluoromethyl)pyridine
Purity: >98.0%(GC)
Packaging: 1g
Price: $34
Updated: 2024/03/01

TCI Chemical

Product number: M2191
Product name: 2-Methoxy-3-(trifluoromethyl)pyridine
Purity: >98.0%(GC)
Packaging: 5g
Price: $114
Updated: 2025/07/31

TRC

Product number: M271975
Product name: 2-Methoxy-3-(trifluoromethyl)pyridine
Packaging: 1g
Price: $75
Updated: 2021/12/16

Oakwood

Product number: 006761
Product name: 2-Methoxy-3-(trifluoromethyl)pyridine
Purity: 98%
Packaging: 1g
Price: $10
Updated: 2021/12/16

More

Less

2-Methoxy-3-(trifluoromethyl)pyridine Chemical Properties,Usage,Production

storage

2-Methoxy-3-(trifluoromethyl)pyridine store at room temperature.

Uses

2-Methoxy-3-(trifluoromethyl)pyridine belongs to pyridine derivatives and can be used as pharmaceutical intermediates.

Synthesis

124-41-4

65753-47-1

121643-44-5

2-Chloro-3-trifluoromethylpyridine (3 g, 16.53 mmol) was dissolved in 30 mL of a methanol solution of sodium methanolate (5.4 M). The reaction mixture was stirred at room temperature for 48 hours. After completion of the reaction, the mixture was cooled in an ice bath and extracted three times with dichloromethane (DCM). The organic phases were combined, washed with saturated sodium chloride solution and dried over anhydrous magnesium sulfate. The organic phase was concentrated under reduced pressure to afford 2-methoxy-3-trifluoromethylpyridine as a colorless liquid (2.7 g, 89% yield). The product was characterized by 1H-NMR (400 MHz, DMSO-d6, 298 K): δ 3.98 (s, 3H), 7.2 (dd, 1H), 8.11 (d, 1H), 8.45 (d, 1H). Mass Spectrometry (MS): m/z 178.1 [M+1]+, retention time (Rt) = 1.29 min.

References

[1] Patent: WO2013/57711, 2013, A1. Location in patent: Page/Page column 45-46
[2] Patent: WO2013/88404, 2013, A1. Location in patent: Page/Page column 92
[3] Patent: US2015/342951, 2015, A1. Location in patent: Paragraph 0841-0842

2-Methoxy-3-(trifluoromethyl)pyridine Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

2-Methoxy-3-(trifluoromethyl)pyridine Suppliers

Americas 1 Belgium 1 China 164 Europe 3 France 2 Germany 5 India 6 Italy 1 Japan 1 Switzerland 1 United Kingdom 19 United States 45 Global 249

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
Advantage: 56

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Shanghai Sinch Parmaceuticals Tech. Co. Ltd.

Tel: +86-21-54098501
Fax: +86-21-54096319
Email: sales@sinch.com.cn
Country: China
ProdList: 11598
Advantage: 64

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9310
Advantage: 66

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10186
Advantage: 62

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14101
Advantage: 59

More

Less

View Lastest Price from 2-Methoxy-3-(trifluoromethyl)pyridine manufacturers

Hefei Lbao Physical & Chemical Science Co.,Ltd

Product: 2-Methoxy-3-(trifluoromethyl)pyridine 121643-44-5
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: Customise
Release date: 2025-11-28

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 2-Methoxy-3-(trifluoromethyl)pyridine 121643-44-5
Price: US $2.20-8.80/kg
Min. Order: 1kg
Purity: 99%min
Supply Ability: 1000kg
Release date: 2025-06-13

PNP Biotech Co. Ltd

Product: 2-Methoxy-3-(trifluoromethyl)pyridine 121643-44-5
Price: US $0.00/kg
Min. Order: 25kg
Purity: 98%
Supply Ability: Inquiry
Release date: 2023-07-10

121643-44-5, 2-Methoxy-3-(trifluoromethyl)pyridineRelated Search:

4-(Trifluoromethoxy)aniline 2-Methoxypyridine 3-(Trifluoromethyl)benzaldehyde 2,6-Lutidine 2-(Trifluoromethoxy)aniline 2-Methoxy-6-methylaminopyridine 2-(Trifluoromethyl)pyridine 3-Trifluoromethylpyridine 2,4,6-Collidine Pyridine (Trifluoromethoxy)benzene 4-Methylpyridine 3-BROMO-5-CHLORO-2-METHOXY-PYRIDINE 3-BROMO-2-METHOXY-6-PICOLINE 3-BROMO-5-FLUORO-2-METHOXYPYRIDINE 5-AMINO-3-BROMO-2-METHOXYPYRIDINE 2-Methoxy-3-nitropyridine 5-BROMO-2-METHOXY-3-NITRO-PYRIDINE

2-Methoxy-3-(trifluoromethyl)pyridine 98%

2-Methoxy-3-(trifluoromethyl)pyridine98%

BUTTPARK 45\01-90

METHOXY-3-TRIFLUOROMETHYLPYRIDINE

3-(trifluoroMethyl)-2-Methoxypyridine

2-METHOXY-3-(TRIFLUOROMETHYL)PYRIDINE

2-Methoxy-3-(trifluoromethyl)pyridine&gt

2-Bromo-7-(trifluoromethyl)pyridine

2-Methoxy-3-(trifluoromethyl)pyridine ISO 9001：2015 REACH

121643-44-5

Pyridines

Heterocyclic Building Blocks

C7 and C8

Building Blocks

C7 and C8

Heterocyclic Building Blocks

Pyridines

Pyridine