ChemicalBook > CAS DataBase List > 2-Amino-5-bromo-6-methylpyridine
2-Amino-5-bromo-6-methylpyridine
Application- Product Name
- 2-Amino-5-bromo-6-methylpyridine
- CAS No.
- 42753-71-9
- Chemical Name
- 2-Amino-5-bromo-6-methylpyridine
- Synonyms
- 5-BROMO-6-METHYLPYRIDIN-2-AMINE;6-AMINO-3-BROMO-2-PICOLINE;5-BROMO-6-METHYL-PYRIDIN-2-YLAMINE;ASISCHEM W51193;BUTTPARK 43\57-95;AKOS BBS-00004445;TIMTEC-BB SBB000260;6-Amino-3-bromo-2-methyL;2-AMINO-5-BROMO-6-PICOLINE;5-fluoro-2-pyridin-2-amine
- CBNumber
- CB8188979
- Molecular Formula
- C6H7BrN2
- Formula Weight
- 187.04
- MOL File
- 42753-71-9.mol
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2-Amino-5-bromo-6-methylpyridine Property
- Melting point:
- 79-84 °C(lit.)
- Boiling point:
- 234.3±35.0 °C(Predicted)
- Density
- 1.5672 (rough estimate)
- refractive index
- 1.5500 (estimate)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- pka
- 4.80±0.37(Predicted)
- form
- Fluffy Powder
- color
- White to off-white
- Sensitive
- Hygroscopic
- BRN
- 114140
- InChI
- InChI=1S/C6H7BrN2/c1-4-5(7)2-3-6(8)9-4/h2-3H,1H3,(H2,8,9)
- InChIKey
- SEOZHXRTVJPQPZ-UHFFFAOYSA-N
- SMILES
- C1(N)=NC(C)=C(Br)C=C1
- CAS DataBase Reference
- 42753-71-9(CAS DataBase Reference)
- EPA Substance Registry System
- 2-Pyridinamine, 5-bromo-6-methyl- (42753-71-9)
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Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36-26/37/39
- WGK Germany
- 3
- TSCA
- Yes
- HazardClass
- IRRITANT
- HS Code
- 29333999
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 548405
- Product name
- 6-Amino-3-bromo-2-methylpyridine
- Purity
- 97%
- Packaging
- 5g
- Price
- $48.7
- Updated
- 2023/06/20
TCI Chemical
- Product number
- A1889
- Product name
- 6-Amino-3-bromo-2-methylpyridine
- Purity
- >98.0%(GC)(T)
- Packaging
- 1g
- Price
- $17
- Updated
- 2025/07/31
TCI Chemical
- Product number
- A1889
- Product name
- 6-Amino-3-bromo-2-methylpyridine
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $66
- Updated
- 2025/07/31
TRC
- Product number
- A594933
- Product name
- 6-Amino-3-bromo-2-picoline
- Packaging
- 500mg
- Price
- $45
- Updated
- 2021/12/16
Matrix Scientific
- Product number
- 001583
- Product name
- 6-Amino-3-bromo-2-methylpyridine
- Purity
- 96%
- Packaging
- 5g
- Price
- $10
- Updated
- 2021/12/16
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2-Amino-5-bromo-6-methylpyridine Chemical Properties,Usage,Production
Application
2-Amino-5-bromo-6-methylpyridine is an important chemical raw material or intermediate, widely used in the synthesis of pyridine drugs, and also has potential effects such as antibacterial, antidepressant, insecticidal, herbicidal, and antimicrobial properties.
Chemical Properties
Light yellow Cryst
Synthesis
3430-17-9
42753-71-9
General steps: Example 2 Add 650 g of xylene as solvent to the reactor and heat to 115-120°C. The heating was continued under reflux conditions until the water was completely removed. The solvent was cooled to 70°C under nitrogen protection. Subsequently, 22 g of sodium amide was added and the solution was heated to 118-120 °C. Under reflux condition, 102 g of 2-bromo-3-methylpyridine was slowly added dropwise, and after completion of the dropwise addition, the reaction temperature was maintained at reflux for 1 hour. Upon completion of the reaction, the reaction solution was cooled to 45 °C. The reaction solution was then poured into ice water and the upper organic phase was separated. The xylene was concentrated under atmospheric pressure to 220 g remaining and cooled to 10-15 °C with stirring. After crystallization, 100 g of the target product 2-amino-5-bromo-6-methylpyridine was obtained with 99.3% purity and 90.1% yield.
References
[1] Patent: CN105348181, 2016, A. Location in patent: Paragraph 0023; 0024; 0025
2-Amino-5-bromo-6-methylpyridine Preparation Products And Raw materials
Raw materials
FUMING SULFURIC ACID
2-Amino-6-methylpyridine
Ethyl acetate
Bromine
Dichloromethane
Sodium hydroxide
PETROLEUM ETHER
Sulfuric acid
Preparation Products
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View Lastest Price from 2-Amino-5-bromo-6-methylpyridine manufacturers
Shaanxi Dideu New Materials Co. Ltd
- Product
- 2-Amino-5-bromo-6-methylpyridine 42753-71-9
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-05-29
Hebei Chuanghai Biotechnology Co,.LTD
- Product
- 2-Amino-5-bromo-6-methylpyridine 42753-71-9
- Price
- US $5.00-2.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10000kg
- Release date
- 2024-08-20
Henan Fengda Chemical Co., Ltd
- Product
- 2-Amino-5-bromo-6-methylpyridine 42753-71-9
- Price
- US $5.00-0.10/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-09
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