ChemicalBook > CAS DataBase List > Ethyl 6-aminoimidazo[1,2-a]pyridine-2-carboxylate

Ethyl 6-aminoimidazo[1,2-a]pyridine-2-carboxylate

Product Name
Ethyl 6-aminoimidazo[1,2-a]pyridine-2-carboxylate
CAS No.
158980-21-3
Chemical Name
Ethyl 6-aminoimidazo[1,2-a]pyridine-2-carboxylate
Synonyms
6-AMINOIMIDAZO[1,2-A]PYR;Ethyl 6-aMinoiMidazo[1,2-a]pyridin-2-carboxylate;ETHYL 6-AMINO-IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLATE;6-AMINOIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER;Ethyl 6-aminoimidazo[1,2-a]pyridine-2-carboxylate USP/EP/BP;6-amino-2-imidazo[1,2-a]pyridinecarboxylic acid ethyl ester;Imidazo[1,2-a]pyridine-2-carboxylic acid, 6-amino-, ethyl ester;6-AMINOIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER, 95+%;Imidazo[1,2-a]pyridine-2-carboxylic acid, 6-amino-, ethyl ester (9CI);6-amino-Imidazo[1,2-a]pyridine-2-carboxylic acid ethyl ester (9CI ACI)
CBNumber
CB8189587
Molecular Formula
C10H11N3O2
Formula Weight
205.21
MOL File
158980-21-3.mol
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Ethyl 6-aminoimidazo[1,2-a]pyridine-2-carboxylate Property

Density 
1.35±0.1 g/cm3(Predicted)
storage temp. 
2-8°C(protect from light)
pka
3.98±0.50(Predicted)
Appearance
Light green to green Solid
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Safety

Hazard Codes 
Xi
Risk Statements 
43
Safety Statements 
36/37
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
A612575
Product name
6-Aminoimidazo[1,2-a]pyridine-2-carboxylicacidethylester
Packaging
500mg
Price
$100
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0960372
Product name
6-AMINOIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER
Purity
95.00%
Packaging
5G
Price
$1739.43
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0960372
Product name
6-AMINOIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER
Purity
95.00%
Packaging
10G
Price
$2413.95
Updated
2021/12/16
Matrix Scientific
Product number
071818
Product name
Ethyl 6-aminoimidazo[1,2-a]pyridine-2-carboxylate
Purity
95+%
Packaging
1g
Price
$142
Updated
2021/12/16
AK Scientific
Product number
W3450
Product name
Ethyl6-aminoimidazo[1,2-a]pyridine-2-carboxylate
Packaging
10g
Price
$771
Updated
2021/12/16
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Ethyl 6-aminoimidazo[1,2-a]pyridine-2-carboxylate Chemical Properties,Usage,Production

Synthesis

38923-08-9

158980-21-3

General procedure for the synthesis of ethyl 6-aminoimidazo[1,2-a]pyridine-2-carboxylate from ethyl 6-nitroimidazo[1,2-A]pyridine-2-carboxylate: 250 mg (1.01 mmol) of ethyl 6-nitroimidazo[1,2-a]pyridine-2-carboxylate was dissolved in 20 ml of ethanol at room temperature, and 30 mg of palladium (10% activated carbon) was added as a catalyst, the hydrogenation reaction was carried out and the reaction lasted for 5 hours at standard atmospheric pressure. After completion of the reaction, the reaction mixture was filtered through diatomaceous earth and the residue was washed with ethanol. The filtrates were combined, concentrated and dried under reduced pressure to give 215 mg of product (quantitative yield). The product was analyzed by LC/MS (Method 5): r = 1.40 mm; MS (ESIpos): m/z = 206 (M + H). 1H-NMR (400 MHz, DMSO-d5) data: δ [ppm] = 8.33 (s, 1H), 7.66 (s, 1H), 7.37 (d, 1H), 6.94 (dd, 1H). 5.11 (s, 2H), 4.26 (q, 2H), 1.29 (t, 3H).

References

[1] Patent: US2016/272637, 2016, A1. Location in patent: Paragraph 0500; 0501; 0502; 0503
[2] Heterocycles, 1994, vol. 38, # 7, p. 1527 - 1532
[3] Molecular Pharmaceutics, 2015, vol. 12, # 6, p. 1813 - 1835
[4] Patent: WO2015/185142, 2015, A1. Location in patent: Page/Page column 20; 21
[5] Patent: WO2008/100423, 2008, A1. Location in patent: Page/Page column 111

Ethyl 6-aminoimidazo[1,2-a]pyridine-2-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Ethyl 6-aminoimidazo[1,2-a]pyridine-2-carboxylate manufacturers

Career Henan Chemical Co
Product
Ethyl 6-aminoimidazo[1,2-a]pyridine-2-carboxylate 158980-21-3
Price
US $1.00/KG
Min. Order
1KG
Purity
95-99%
Supply Ability
1ton
Release date
2020-01-02

158980-21-3, Ethyl 6-aminoimidazo[1,2-a]pyridine-2-carboxylateRelated Search:


  • ETHYL 6-AMINO-IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLATE
  • 6-AMINOIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER
  • Imidazo[1,2-a]pyridine-2-carboxylic acid, 6-amino-, ethyl ester (9CI)
  • 6-AMINOIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER, 95+%
  • Ethyl 6-aMinoiMidazo[1,2-a]pyridin-2-carboxylate
  • Imidazo[1,2-a]pyridine-2-carboxylic acid, 6-amino-, ethyl ester
  • 6-AMINOIMIDAZO[1,2-A]PYR
  • 6-amino-2-imidazo[1,2-a]pyridinecarboxylic acid ethyl ester
  • Ethyl 6-aminoimidazo[1,2-a]pyridine-2-carboxylate USP/EP/BP
  • Imidazo[1,2-a]pyridine-2-carboxylic acid, 6-amino-, ethyl ester (9CI, ACI)
  • 6-amino-Imidazo[1,2-a]pyridine-2-carboxylic acid ethyl ester (9CI ACI)
  • 158980-21-3
  • Heterocycle-Pyridine series
  • AMINOACID