ChemicalBook > CAS DataBase List > 5-Nitrobenzothiophene

5-Nitrobenzothiophene

Product Name
5-Nitrobenzothiophene
CAS No.
4965-26-8
Chemical Name
5-Nitrobenzothiophene
Synonyms
5-nitrobenzo[b]thiophene;5-NITROBENZOTHIOPHENE;5-nitro-1-benzothiophene;Benzo[b]thiophene, 5-nitro-;5-Nitrobenzothiophene ISO 9001：2015 REACH
CBNumber
CB8208222
Molecular Formula
C8H5NO2S
Formula Weight
179.2
MOL File
4965-26-8.mol
More
Less

5-Nitrobenzothiophene Property

Melting point:
149-150 °C
Boiling point:
324.6±15.0 °C(Predicted)
Density 
1.435±0.06 g/cm3(Predicted)
storage temp. 
2-8°C(protect from light)
Appearance
Light yellow to brown Solid
More
Less

Safety

HS Code 
2934999090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

TRC
Product number
N495033
Product name
5-Nitrobenzo[b]thiophene
Packaging
100mg
Price
$60
Updated
2021/12/16
ChemScene
Product number
CS-W006433
Product name
5-Nitrobenzo[b]thiophene
Purity
≥98.0%
Packaging
250mg
Price
$61
Updated
2021/12/16
Apolloscientific
Product number
OR938440
Product name
5-Nitrobenzothiophene
Purity
95%
Packaging
250mg
Price
$115
Updated
2021/12/16
AK Scientific
Product number
Y9213
Product name
5-Nitrobenzo[b]thiophene
Packaging
250mg
Price
$154
Updated
2021/12/16
ChemScene
Product number
CS-W006433
Product name
5-Nitrobenzo[b]thiophene
Purity
≥98.0%
Packaging
5g
Price
$188
Updated
2021/12/16
More
Less

5-Nitrobenzothiophene Chemical Properties,Usage,Production

Synthesis

6345-55-7

4965-26-8

5-Nitro-1-benzothiophene-2-carboxylic acid (40 g, 179 mmol) was dissolved in quinoline (350 mL) under mechanical stirring followed by addition of copper powder (11.3 g, 179 mmol). The reaction mixture was heated to 190°C until complete gas release. After completion of the reaction, the mixture was cooled to room temperature and poured into crushed ice and acidified with concentrated hydrochloric acid. The resulting suspension was extracted with ethyl acetate and the organic layer was separated and washed sequentially with 2N hydrochloric acid, water and saturated brine. The organic layer was dried over anhydrous sodium sulfate and concentrated to give 5-nitrobenzothiophene (30.5 g, 95% yield). The structure of the product was confirmed by 1H NMR (DMSO-d6, 400 MHz) and LC-MS (electrospray): 1H NMR δ 8.85 (d, 1H), 8.31 (d, 1H), 8.18 (dd, 1H), 8.06 (d, 1H), 7.73 (d, 1H); LC-MS m/z = 180 [M + H]+.

References

[1] Bioorganic and Medicinal Chemistry, 2016, vol. 24, # 3, p. 403 - 427
[2] ACS Medicinal Chemistry Letters, 2016, vol. 7, # 8, p. 735 - 740
[3] ACS Medicinal Chemistry Letters, 2017, vol. 8, # 3, p. 338 - 343
[4] Patent: WO2006/66172, 2006, A1. Location in patent: Page/Page column 27
[5] Synthetic Communications, 1991, vol. 21, # 7, p. 959 - 964

5-Nitrobenzothiophene Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

5-Nitrobenzothiophene Suppliers

Belgium 1 China 64 Germany 1 India 1 Switzerland 1 United Kingdom 6 United States 12 Global 86
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
18270980682
Fax
021 51613951
Email
mlcheng@sunwaypharm.cn
Country
China
ProdList
8669
Advantage
57
Wuhan Haizheng Industry & Trade Development Co. Ltd
Tel
027-8866 0053/88660577/88660578
Fax
027-8899 1911
Country
China
ProdList
1073
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
HangZhou YuHao Chemical Technology Co., Ltd.
Tel
0571-82693216
Fax
0571-82880190
Email
info@yuhaochemical.com
Country
China
ProdList
2028
Advantage
58
Zhengzhou Alfachem Co., Ltd.
Tel
0371-53765687 18937137882
Fax
QQ:2885373884
Email
2853979813@qq.com
Country
China
ProdList
7991
Advantage
55
Yancheng KangdiSen Pharmaceutical Co., Ltd.
Tel
13812573443
Fax
-
Email
tongbenwan22@163.com
Country
China
ProdList
1980
Advantage
55
Henan CoreyChem Co., Ltd
Tel
0371-86658258
Fax
0371-60996044
Email
info@coreychem.com
Country
China
ProdList
10453
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Henan Anky Chemical Technology Co., Ltd.
Tel
17836913271
Fax
0374-8348899
Email
3224305243@qq.com
Country
China
ProdList
2952
Advantage
58
Wuxi KaideRui Pharmaceutical Technology Co., Ltd
Tel
19906241957
Fax
-
Email
1557216087@qq.com
Country
China
ProdList
1837
Advantage
55
Biokitchen
Tel
021-021-021-31663258 13795219287
Fax
021-31663258
Email
donghuanwen@126.com
Country
China
ProdList
8816
Advantage
58
Aikon International Limited
Tel
025-58859352 18068836627
Fax
(5)02557626880
Email
dt3@aikonchem.com
Country
China
ProdList
15493
Advantage
58
Bejing Famous Pharmaceutical Technology Co., Ltd.
Tel
13331045123
Fax
86-10-80339217
Email
2559355526@qq.com
Country
China
ProdList
14193
Advantage
58
Zhengzhou Acme Chemical Co., Ltd.
Tel
0371-037163312495,13303845143 13303845143
Fax
QQ3001379618
Email
3001379618@qq.com
Country
China
ProdList
10267
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52687
Advantage
58
Chengdu Feibai Pharmaceutical Co., Ltd.
Tel
028-84641798 18782128315
Email
3302391190@qq.com
Country
China
ProdList
9800
Advantage
55
Xinyi Kaiwu Chemical Technology Co., Ltd.
Tel
0516-0516-88997009 18651776937
Email
4164357@qq.com
Country
China
ProdList
3204
Advantage
58
Dideu Industries Group Limited
Tel
+86-29-89586680 +86-15129568250
Email
1026@dideu.com
Country
China
ProdList
20284
Advantage
58
Hefei TNJ Chemical Industry Co.,Ltd.
Tel
+86-0551-65418671 +8618949823763
Fax
0551-65418697
Email
sales@tnjchem.com
Country
China
ProdList
34563
Advantage
58
Unipharm pharmaceutical industry Co., Ltd
Tel
536-8266195 +8613953676784
Email
lee@unipharm-sd.com
Country
China
ProdList
1202
Advantage
58
Dayang Chem (Hangzhou) Co.,Ltd.
Tel
+86-0571-88938639 +8617705817739
Fax
+86-571-88938652，+86-571- 88492614
Email
info@dycnchem.com
Country
China
ProdList
52846
Advantage
58
Blocksynth Pharmaceutical Technology Co.,Ltd
Tel
0086-19817745290; +8619817745290
Email
bd@blocksynth.com
Country
China
ProdList
5661
Advantage
58
Shanghai Lanle Bird Industrial Co., Ltd.
Tel
15021845385
Email
765325601@qq.com
Country
China
ProdList
3609
Advantage
58
Shanghai Chuangtuo Biotechnology Co., Ltd.
Tel
021-64301660 18121334283
Email
sales@chuangtuobio.com
Country
China
ProdList
175
Advantage
58
Wuxi Kehua Biological Technology Co., Ltd.
Tel
0510-86838766 13636419861
Email
2258830676@qq.com
Country
China
ProdList
5044
Advantage
58
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Email
sales@accelachem.com
Country
China
ProdList
10467
Advantage
58
Changzhou Yinghao Technology Development Co., Ltd
Tel
15151934985
Email
sales@yingsapharm.com
Country
China
ProdList
5181
Advantage
58
CONIER CHEM AND PHARMA LIMITED
Tel
+8618523575427
Email
sales@conier.com
Country
China
ProdList
49975
Advantage
58
Shanghai Kaiwei Chemical Technology Co., Ltd.
Tel
021-58461859 15821823057
Email
service@aiviche.com
Country
China
ProdList
49312
Advantage
58
career henan chemical co
Tel
+86-0371-86658258 +8613203830695
Fax
0086-371-86658258
Email
factory@coreychem.com
Country
China
ProdList
29798
Advantage
58
Neostar United (Changzhou) Industrial Co., Ltd.
Tel
+86-0519-85551759 +8613506123987
Fax
+0086-519-85557389
Email
marketing1@neostarunited.com
Country
China
ProdList
8830
Advantage
58
Zhende Chemical Technology (Shanghai) Co., Ltd.
Tel
15601952568
Fax
3004479441
Email
sales4@myuchem.com
Country
China
ProdList
2994
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing@energy-chemical.com
Country
China
ProdList
44918
Advantage
58
Nanjing Puxin Pharmaceutical Technology Co., Ltd
Tel
17366295326
Fax
QQ360829978
Email
puxinpharma_2017@126.com
Country
China
ProdList
2444
Advantage
58
TCI (Shanghai) Chemical Trading Co., Ltd.
Tel
021-61109150
Fax
021-61105897
Email
sales@tcisct.com
Country
China
ProdList
29668
Advantage
58
Ningbo jinuo chemical co., LTD
Tel
0574-87314919 057487319282
Email
info@nbinno.com
Country
China
ProdList
7047
Advantage
58
Nanjing Yili Biotechnology Co., Ltd.
Tel
15380789538
Email
2885743537@qq.com
Country
China
ProdList
8205
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 4008210725
Email
malulu@leyan.com
Country
China
ProdList
40000
Advantage
58
Bide Pharmatech Ltd.
Tel
400-6005915
Email
sales@picasso-e.com
Country
China
ProdList
39653
Advantage
58
Jiaxing Zhejia Biotechnology Co., LTD
Tel
0573-85609002 18367600069;
Email
zhejia01@163.com
Country
China
ProdList
8887
Advantage
58
Zhengzhou Deyuankai Chemical Co., LTD
Tel
17837139533
Email
1165412154@qq.com
Country
China
ProdList
7740
Advantage
58
Pushan Industry (Shaanxi) Co., Ltd.
Tel
029-81310890 13571859809
Email
info@pushanshiye.com
Country
China
ProdList
9955
Advantage
58
Zhengzhou Hong Sheng Pharmaceutical Technology Co. Ltd.
Tel
0371-55695890 15637198702
Email
1677336983@qq.com
Country
China
ProdList
13191
Advantage
58
Shanghai Yanbang Pharmaceutical Technology Co., Ltd
Tel
15618536883
Email
1228181347@qq.com
Country
China
ProdList
7951
Advantage
58
Shaanxi Didu New Material Co., Ltd
Tel
029-81145920 17391631969
Email
1046@dideu.com
Country
China
ProdList
9996
Advantage
58
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 17801761073
Email
Gsiyu@solarbio.com
Country
China
ProdList
50464
Advantage
58
https://hanhongsci.com/
Tel
021-54306202 18917919676
Email
info@hanhongsci.com
Country
China
ProdList
29995
Advantage
58
Ningbo Zhenyue Pharmaceutical Technology Co., Ltd
Tel
19817745290
Email
bd@blocksynth.com
Country
China
ProdList
5870
Advantage
58
Hangzhou Sulfuchem Material Technology Co., Ltd.
Tel
0571-86113725 15372021306
Email
sales@sulfuchem.com
Country
China
ProdList
970
Advantage
58
More
Less

View Lastest Price from 5-Nitrobenzothiophene manufacturers

Career Henan Chemical Co
Product
5-Nitrobenzothiophene 4965-26-8
Price
US $1.00/g
Min. Order
1g
Purity
≥98%
Supply Ability
g/kg/T
Release date
2019-12-24

4965-26-8, 5-NitrobenzothiopheneRelated Search:

5-NITROTHIOPHENE-2-CARBOXALDEHYDE Sodium 3-nitrobenzenesulphonate Dibenzothiophene 5-CHLOROBENZOTHIOPHENE 2-Nitrothiophene 2-Acetylbenzo[b]thiophene 1-Chloro-3-nitrobenzene 4-Nitrobenzoic acid Thianaphthene 5-Nitrothiophene-2-carboxylic acid Thiophene POLYTHIOPHENE 1,3-Dinitrobenzene Nitrobenzene 5-NITROBENZOTHIOPHENE-2-CARBOXYLIC ACID 2-NITRODIBENZOTHIOPHENE Ethyl 6-methyl-5-nitrobenzo[b]thiophene-2-carboxylate 2,8-DINITRODIBENZOTHIOPHENE

  • 5-NITROBENZOTHIOPHENE
  • 5-nitrobenzo[b]thiophene
  • Benzo[b]thiophene, 5-nitro-
  • 5-nitro-1-benzothiophene
  • 5-Nitrobenzothiophene ISO 9001：2015 REACH
  • 4965-26-8
  • C8H5NO2S