3,5-Dichloro-2-cyanopyridine

Product Name: 3,5-Dichloro-2-cyanopyridine
CAS No.: 85331-33-5
Chemical Name: 3,5-Dichloro-2-cyanopyridine
Synonyms: 3,5-dichloropicolinonitrile;3,5-Dichloropyridine-2-carbonitrile;3,5-Dichloropicolinitrile;3,5-DICHLORO-2-CYANOPYRIDINE;2-CYANO-3,5-DICHLOROPYRIDINE;Cyanodichloropyridine 235---;3,5-dichboro-2-cyanopyridine;3,5-Dichloror-2-cyanopyridine;3,5-Dichloro-2-cyanopyridine>3,5-Dichloro-pyridin-2-carbonitrile
CBNumber: CB8232724
Molecular Formula: C6H2Cl2N2
Formula Weight: 173
MOL File: 85331-33-5.mol

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3,5-Dichloro-2-cyanopyridine Property

Melting point:: 101-103°C
Boiling point:: 271.9±35.0 °C(Predicted)
Density: 1.49±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: -4.61±0.10(Predicted)
form: powder to crystal
color: White to Light yellow
BRN: 4390101
InChI: InChI=1S/C6H2Cl2N2/c7-4-1-5(8)6(2-9)10-3-4/h1,3H
InChIKey: ATUOLSDAAPMVJJ-UHFFFAOYSA-N
SMILES: C1(C#N)=NC=C(Cl)C=C1Cl
CAS DataBase Reference: 85331-33-5(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 20/21/22-36/37/38
Safety Statements: 26-36/37/39-36-36/37
RIDADR: 3439
WGK Germany: 3
HazardClass: 6.1
PackingGroup: III
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 736074
Product name: 3,5-Dichloropyridine-2-carbonitrile
Purity: 95%
Packaging: 1g
Price: $30.7
Updated: 2023/01/07

Sigma-Aldrich

Product number: 736074
Product name: 3,5-Dichloropyridine-2-carbonitrile
Purity: 95%
Packaging: 5g
Price: $61.9
Updated: 2023/01/07

TCI Chemical

Product number: D4059
Product name: 3,5-Dichloro-2-cyanopyridine
Purity: >98.0%(GC)
Packaging: 1g
Price: $24
Updated: 2025/07/31

TCI Chemical

Product number: D4059
Product name: 3,5-Dichloro-2-cyanopyridine
Purity: >98.0%(GC)
Packaging: 5g
Price: $73
Updated: 2025/07/31

TRC

Product number: D473985
Product name: 3,5-Dichloropicolinonitrile
Packaging: 500mg
Price: $45
Updated: 2021/12/16

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3,5-Dichloro-2-cyanopyridine Chemical Properties,Usage,Production

Chemical Properties

Yellow to light brown crystalline powder

Uses

3,5-Dichloro-2-cyanopyridine is an intermediate in the industrial synthesis of nicotinic acid and nicotinamide.

Synthesis

15177-57-8

7677-24-9

85331-33-5

General procedure for the synthesis of 2-cyano-3,5-dichloropyridine from 3,5-dichloropyridine 1-oxide and trimethylcyanosilane: 21.8 mL (0.174 mol) of trimethylcyanosilane and 14.6 mL (0.158 mol) of dimethylcarbamoyl chloride were sequentially added to 26 g (0.158 mol) of 3,5-dichloropyridine 1-oxide in an 80-mL dichloromethane solution. The reaction mixture was stirred at room temperature for 48 hours. After the reaction was completed, 100 mL of 10% aqueous NaHCO3 solution was added and stirred vigorously for 10 minutes. After separating the organic and aqueous phases, the aqueous phase was extracted once with dichloromethane. All organic phases were combined, dried with anhydrous sodium sulfate and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography using dichloromethane as eluent. The target fraction was collected, concentrated and recrystallized from a small amount of methanol to give 11 g (40.2% yield) of 2-cyano-3,5-dichloropyridine with a melting point of 102 °C. The target fraction was collected, concentrated and recrystallized from a small amount of methanol.

References

[1] Patent: US2003/232842, 2003, A1. Location in patent: Page 8

3,5-Dichloro-2-cyanopyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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3,5-Dichloro-2-cyanopyridine Suppliers

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View Lastest Price from 3,5-Dichloro-2-cyanopyridine manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 3,5-Dichloro-2-cyanopyridine 85331-33-5
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10000KGS
Release date: 2025-06-03

Jinan Finer Chemical Co., Ltd

Product: 3,5-Dichloro-2-cyanopyridine 85331-33-5
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100mt
Release date: 2021-11-23

Hebei Zhuanglai Chemical Trading Co Ltd

Product: 3,5-Dichloro-2-cyanopyridine 85331-33-5
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 ton
Release date: 2024-11-18

85331-33-5, 3,5-Dichloro-2-cyanopyridineRelated Search:

2,3-Dichloropyridine 2,5-Dichloropyridine 2-Cyanopyridine 3-Aminopyridine Clopyralid 2-Chloro-5-chloromethylpyridine 3,5-Dichloropyridine 5-Bromo-3-nitropyridine-2-carbonitrile 2-Cyano-3-fluoropyridine 5-bromo-3-methylpicolinonitrile 2-Cyano-3-chloropyridine 2-Cyano-3,5-difluoropyridine 3-bromo-5-chloropyridine-2-carbonitrile 5-bromo-3-chloropyridine-2-carbonitrile 2-Cyano-3-trifluoromethylpyridine 5-Chloro-3-nitropyridine-2-carbonitrile 5-Bromo-3-fluoro-pyridine-2-carbonitrile 3-Bromo-5-methylpyridine-2-carbonitrile

3,5-dichloropicolinonitrile

2-PYRIDINECARBONITRILE, 3,5-DICHLORO-

2-CYANO-3,5-DICHLOROPYRIDINE

3,5-DICHLORO-2-CYANOPYRIDINE

3,5-Dichloropicolinitrile

3,5-Dichloropyridine-2-carbonitrile

Cyanodichloropyridine 235---

3,5-Dichloro-2-pyridinecarbonitrile

3,5-Dichloro-pyridin-2-carbonitrile

2-Cyano-3,5-dichloropyridine, 3,5-Dichloropicolinonitrile

3,5-Dichloro-2-cyanopyridine&gt

3,5-Dichloro-2-cyanopyridine ISO 9001：2015 REACH

3,5-dichboro-2-cyanopyridine

3,5-Dichloror-2-cyanopyridine

85331-33-5

85331-28-7

85311-33-5

C6H2C12N2

Building Blocks

Chemical Synthesis

Heterocyclic Building Blocks

Pyridines, Pyrimidines, Purines and Pteredines

Pyridine series

Pyridines

Pyridine

Pyridines derivates

C6