3,5-Dichloro-2-cyanopyridine
- Product Name
- 3,5-Dichloro-2-cyanopyridine
- CAS No.
- 85331-33-5
- Chemical Name
- 3,5-Dichloro-2-cyanopyridine
- Synonyms
- 3,5-dichloropicolinonitrile;3,5-Dichloropyridine-2-carbonitrile;3,5-Dichloropicolinitrile;3,5-DICHLORO-2-CYANOPYRIDINE;2-CYANO-3,5-DICHLOROPYRIDINE;Cyanodichloropyridine 235---;3,5-dichboro-2-cyanopyridine;3,5-Dichloror-2-cyanopyridine;3,5-Dichloro-2-cyanopyridine>3,5-Dichloro-pyridin-2-carbonitrile
- CBNumber
- CB8232724
- Molecular Formula
- C6H2Cl2N2
- Formula Weight
- 173
- MOL File
- 85331-33-5.mol
3,5-Dichloro-2-cyanopyridine Property
- Melting point:
- 101-103°C
- Boiling point:
- 271.9±35.0 °C(Predicted)
- Density
- 1.49±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- -4.61±0.10(Predicted)
- form
- powder to crystal
- color
- White to Light yellow
- BRN
- 4390101
- InChI
- InChI=1S/C6H2Cl2N2/c7-4-1-5(8)6(2-9)10-3-4/h1,3H
- InChIKey
- ATUOLSDAAPMVJJ-UHFFFAOYSA-N
- SMILES
- C1(C#N)=NC=C(Cl)C=C1Cl
- CAS DataBase Reference
- 85331-33-5(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 20/21/22-36/37/38
- Safety Statements
- 26-36/37/39-36-36/37
- RIDADR
- 3439
- WGK Germany
- 3
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 736074
- Product name
- 3,5-Dichloropyridine-2-carbonitrile
- Purity
- 95%
- Packaging
- 1g
- Price
- $30.7
- Updated
- 2023/01/07
- Product number
- 736074
- Product name
- 3,5-Dichloropyridine-2-carbonitrile
- Purity
- 95%
- Packaging
- 5g
- Price
- $61.9
- Updated
- 2023/01/07
- Product number
- D4059
- Product name
- 3,5-Dichloro-2-cyanopyridine
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $24
- Updated
- 2025/07/31
- Product number
- D4059
- Product name
- 3,5-Dichloro-2-cyanopyridine
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $73
- Updated
- 2025/07/31
- Product number
- D473985
- Product name
- 3,5-Dichloropicolinonitrile
- Packaging
- 500mg
- Price
- $45
- Updated
- 2021/12/16
3,5-Dichloro-2-cyanopyridine Chemical Properties,Usage,Production
Chemical Properties
Yellow to light brown crystalline powder
Uses
3,5-Dichloro-2-cyanopyridine is an intermediate in the industrial synthesis of nicotinic acid and nicotinamide.
Synthesis
15177-57-8
7677-24-9
85331-33-5
General procedure for the synthesis of 2-cyano-3,5-dichloropyridine from 3,5-dichloropyridine 1-oxide and trimethylcyanosilane: 21.8 mL (0.174 mol) of trimethylcyanosilane and 14.6 mL (0.158 mol) of dimethylcarbamoyl chloride were sequentially added to 26 g (0.158 mol) of 3,5-dichloropyridine 1-oxide in an 80-mL dichloromethane solution. The reaction mixture was stirred at room temperature for 48 hours. After the reaction was completed, 100 mL of 10% aqueous NaHCO3 solution was added and stirred vigorously for 10 minutes. After separating the organic and aqueous phases, the aqueous phase was extracted once with dichloromethane. All organic phases were combined, dried with anhydrous sodium sulfate and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography using dichloromethane as eluent. The target fraction was collected, concentrated and recrystallized from a small amount of methanol to give 11 g (40.2% yield) of 2-cyano-3,5-dichloropyridine with a melting point of 102 °C. The target fraction was collected, concentrated and recrystallized from a small amount of methanol.
References
[1] Patent: US2003/232842, 2003, A1. Location in patent: Page 8
3,5-Dichloro-2-cyanopyridine Preparation Products And Raw materials
Raw materials
Preparation Products
3,5-Dichloro-2-cyanopyridine Suppliers
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- --
- Fax
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- brian@chordip.com
- Country
- Jordan
- ProdList
- 704
- Advantage
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View Lastest Price from 3,5-Dichloro-2-cyanopyridine manufacturers
- Product
- 3,5-Dichloro-2-cyanopyridine 85331-33-5
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-06-03
- Product
- 3,5-Dichloro-2-cyanopyridine 85331-33-5
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100mt
- Release date
- 2021-11-23
- Product
- 3,5-Dichloro-2-cyanopyridine 85331-33-5
- Price
- US $10.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20 ton
- Release date
- 2024-11-18