ChemicalBook > CAS DataBase List > 7-Hydroxygranisetron

7-Hydroxygranisetron

Product Name
7-Hydroxygranisetron
CAS No.
4498-67-3
Chemical Name
7-Hydroxygranisetron
Synonyms
INDAPAMIDE;1H-INDAZOLE-3-CARBOXYLIC ACID;INDAZOLE-3-CARBOXYLIC ACID;1H-INDAZOL-3-CARBONIC ACID;NSC 520610;AKOS BB-9978;3-CARBOXYINDAZOLE;Indazole - 3 - carbo;3-Carboxy-1H-indazole;Indazole-3-carboxylicaci
CBNumber
CB8247050
Molecular Formula
C8H6N2O2
Formula Weight
162.15
MOL File
4498-67-3.mol
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7-Hydroxygranisetron Property

Melting point:
266-270 °C (dec.)
Boiling point:
443.7±18.0 °C(Predicted)
Density 
1.506±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
3.03±0.10(Predicted)
form 
powder
color 
beige
BRN 
6354
InChI
InChI=1S/C8H6N2O2/c11-8(12)7-5-3-1-2-4-6(5)9-10-7/h1-4H,(H,9,10)(H,11,12)
InChIKey
BHXVYTQDWMQVBI-UHFFFAOYSA-N
SMILES
N1C2=C(C=CC=C2)C(C(O)=O)=N1
CAS DataBase Reference
4498-67-3(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-36-36/37/38
Safety Statements 
26-36/37/39-22
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
56915
Product name
Indazole-3-carboxylic acid
Purity
≥97.0% (HPLC)
Packaging
10g
Price
$138
Updated
2023/06/20
Sigma-Aldrich
Product number
56915
Product name
Indazole-3-carboxylic acid
Purity
≥97.0% (HPLC)
Packaging
50g
Price
$468
Updated
2023/06/20
TCI Chemical
Product number
I0672
Product name
Indazole-3-carboxylic Acid
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$21
Updated
2024/03/01
TCI Chemical
Product number
I0672
Product name
Indazole-3-carboxylic Acid
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$57
Updated
2024/03/01
Alfa Aesar
Product number
H64001
Product name
1H-Indazole-3-carboxylic acid, 98%
Packaging
5g
Price
$29.65
Updated
2024/03/01
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7-Hydroxygranisetron Chemical Properties,Usage,Production

Chemical Properties

yellow crystal

Uses

Indazole-3-carboxylic acid may be used in the synthesis of the following:

  • N-(8-methyl-azabicyclo[3.2.11]oct-3-yl)-1H-indazole-3-carboxamide
  • N-(1- benzyl-4-methylhexahydro-1H-1,4-diazepin-6-yl)-1H-indazole-3-carboxamide
  • 1H-indazole-3-carboxamide

Uses

Indazole-3-carboxylic acid is indole derivatives useful in treatment of pain and inflammation

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 26, p. 531, 1989 DOI: 10.1002/jhet.5570260251

7-Hydroxygranisetron Preparation Products And Raw materials

Raw materials

Stannous chloride dihydrate Isatin Stannous chloride Sodium nitrite Hydrochloric acid Acetic acid Sodium hydroxide Sulfuric acid

Preparation Products

3-Methylindole Lonidamine
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View Lastest Price from 7-Hydroxygranisetron manufacturers

Dorne Chemical Technology co. LTD
Product
7-Hydroxygranisetron 4498-67-3
Price
US $1.00/ASSAYS
Min. Order
1ASSAYS
Purity
99%
Supply Ability
1000kg
Release date
2024-03-26
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Product
7-Hydroxygranisetron 4498-67-3
Price
US $500.00-300.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000
Release date
2024-08-23
Hebei Zhuanglai Chemical Trading Co Ltd
Product
Indazole-3-carboxylic acid 4498-67-3
Price
US $150.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
500kg
Release date
2024-11-28

4498-67-3, 7-HydroxygranisetronRelated Search:

Calconcarboxylic acid Citric acid Folic acid 1-Methylindazole-3-carboxylic acid Ethyl 2-(Chlorosulfonyl)acetate 1H-INDAZOLE-4-CARBOXYLIC ACID Indazole Indazole-4-boronic acid, hydrochloride 1H-INDAZOLE-5-BORONIC ACID 6-INDAZOLYBORONIC ACID Indometacin INDOMETHACIN SODIUM 7-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-1H-INDAZOLE Methyl indole-6-carboxylate 1H-[1,2,3]TRIAZOLE-4-CARBALDEHYDE 6-Hydroxyindole Indole-4-carboxylic acid Ascoric Acid

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  • 4498-67-3
  • 581083-36-9
  • 498-67-3
  • C8H6N2O2
  • Heterocyclic Building Blocks
  • Indazoles
  • Building Blocks
  • Indoles and derivatives
  • pharmacetical
  • Carboxylic Acids
  • Organic acids
  • Acids and Derivatives
  • Heterocycles
  • (intermediate of granisetron)
  • Indazoles
  • Indole Derivatives
  • Carboxylic Acids
  • Fused Ring Systems
  • Building Blocks
  • Heterocyclic Building Blocks
  • PHARMACEUTICAL INTERMEDIATES