ChemicalBook > CAS DataBase List > 1-Chloro-5-isopropoxy-2-methyl-4-nitrobenzene

1-Chloro-5-isopropoxy-2-methyl-4-nitrobenzene

Product Name
1-Chloro-5-isopropoxy-2-methyl-4-nitrobenzene
CAS No.
1032903-50-6
Chemical Name
1-Chloro-5-isopropoxy-2-methyl-4-nitrobenzene
Synonyms
EOS-60654;CR-7-CL,CRT-5;2-Chloro-4-isopropoxy-5-nitrotoluene;4-CHLORO-2-ISOPROPOXY-5-METHYL-NITROBENZ;1-Chloro-5-isopropoxy-2-methyl-4-nitrobenzene;1-Chloro-2-methyl-4-nitro-5-(propan-2-yloxy)benzene;Benzene, 1-chloro-2-methyl-5-(1-methylethoxy)-4-nitro-;4-Chloro-5-methyl-2-[(prop-2-y)loxy]nitrobenzene, 5-Chloro-4-methyl-2-nitrophenyl prop-2-yl ether
CBNumber
CB82489953
Molecular Formula
C10H12ClNO3
Formula Weight
229.66
MOL File
1032903-50-6.mol
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1-Chloro-5-isopropoxy-2-methyl-4-nitrobenzene Property

Boiling point:
333.1±37.0 °C(Predicted)
Density 
1.228
storage temp. 
Sealed in dry,Room Temperature
Appearance
Off-white to light yellow Solid
InChI
InChI=1S/C10H12ClNO3/c1-6(2)15-10-5-8(11)7(3)4-9(10)12(13)14/h4-6H,1-3H3
InChIKey
BXIHEXKVDALKGM-UHFFFAOYSA-N
SMILES
C1(Cl)=CC(OC(C)C)=C([N+]([O-])=O)C=C1C
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Safety

HS Code 
2904200090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TRC
Product number
C382823
Product name
1-Chloro-5-isopropoxy-2-methyl-4-nitrobenzene
Packaging
50mg
Price
$45
Updated
2021/12/16
TRC
Product number
C382823
Product name
1-Chloro-5-isopropoxy-2-methyl-4-nitrobenzene
Packaging
100mg
Price
$90
Updated
2021/12/16
ChemScene
Product number
CS-M2893
Product name
1-Chloro-2-methyl-4-nitro-5-(propan-2-yloxy)benzene
Purity
98.61%
Packaging
250mg
Price
$111
Updated
2021/12/16
Apolloscientific
Product number
OR61251
Product name
2-Chloro-4-isopropoxy-5-nitrotoluene
Packaging
250mg
Price
$144
Updated
2021/12/16
ChemScene
Product number
CS-M2893
Product name
1-Chloro-2-methyl-4-nitro-5-(propan-2-yloxy)benzene
Purity
98.61%
Packaging
1g
Price
$145
Updated
2021/12/16
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1-Chloro-5-isopropoxy-2-methyl-4-nitrobenzene Chemical Properties,Usage,Production

Synthesis

67-63-0

112108-73-3

1032903-50-6

1. 2-Chloro-4-fluoro-5-nitrotoluene (260 g) and potassium hydroxide (116 g) were added to 1.5 L of isopropanol and the reaction was carried out at 20 °C. The progress of the reaction was monitored by TLC until the disappearance of the raw material. 2. After completion of the reaction, the stirring was stopped, and the reaction solution was slowly poured into 5 L of water. 3. The reaction mixture was filtered, and the solid product was collected and washed with an appropriate amount of water. 4. The filter cake was dried. 1-chloro-5-isopropoxy-2-methyl-4-nitrobenzene (271 g) was obtained in 86.3% yield.

References

[1] Journal of Medicinal Chemistry, 2013, vol. 56, # 14, p. 5675 - 5690
[2] Patent: EP3287463, 2018, A1. Location in patent: Paragraph 0164; 0165
[3] Patent: CN106674084, 2017, A. Location in patent: Paragraph 0026; 0027; 0028
[4] Patent: CN106336398, 2017, A. Location in patent: Paragraph 0108; 0127; 0128; 0129
[5] Patent: CN106478700, 2017, A. Location in patent: Paragraph 0093; 0108; 0109; 0110

1-Chloro-5-isopropoxy-2-methyl-4-nitrobenzene Preparation Products And Raw materials

Raw materials

Preparation Products

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1-Chloro-5-isopropoxy-2-methyl-4-nitrobenzene Suppliers

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View Lastest Price from 1-Chloro-5-isopropoxy-2-methyl-4-nitrobenzene manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
1-Chloro-5-isopropoxy-2-methyl-4-nitrobenzene 1032903-50-6
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-30
Nanjing Fred Technology Co., Ltd
Product
1-chloro-5-isopropoxy-2-methyl-4-nitrobenzene 1032903-50-6
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%(HPLC)
Supply Ability
2000kg/Year
Release date
2023-12-14
Zhuozhou Wenxi import and Export Co., Ltd
Product
1-Chloro-5-isopropoxy-2-methyl-4-nitrobenzene 1032903-50-6
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10

1032903-50-6, 1-Chloro-5-isopropoxy-2-methyl-4-nitrobenzeneRelated Search:

tert-butyl 4-(4-aMino-5-isopropoxy-2-Methylphenyl)piperidine-1-carboxylate 4-(5-isopropoxy-2-Methyl-4-nitrophenyl)pyridine Ceritinib (LDK378) LDK-378 dihydrochloride 4-Pyrimidinamine, 2,5-dichloro-N-[2-[(1-methylethyl)sulfonyl]phenyl]- 1-broMo-5-fluoro-2-Methyl-4-nitrobenzene 1-AMINO-2-(ISOPROPYLSULPHONYL)BENZENE 2,4,5-Trichloropyrimidine 1-BroMo-5-isopropoxy-2-Methyl-4-nitrobenzene 5-Methyl-2-(1-Methylethoxy)-4- (4-piperidinyl)- BenzenaMine hydrochloride (1:2)

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