Oxazole-2-amine

Product Name: Oxazole-2-amine
CAS No.: 4570-45-0
Chemical Name: Oxazole-2-amine
Synonyms: oxazol-2-amine;2-AMINO-OXAZOLE;2-OxazolaMine;2-AMINOXAZOLE;Oxazole-2-amine;OXAZOL-2-YLAMINE;OXAZOLE-2-YLAMINE;1,3-OXAZOL-2-AMINE;2-Aminooxazole >2-Aminooxazole,97%
CBNumber: CB8262819
Molecular Formula: C3H4N2O
Formula Weight: 84.08
MOL File: 4570-45-0.mol

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Oxazole-2-amine Property

Melting point:: 93-95℃
Boiling point:: 186.7±23.0 °C(Predicted)
Density: 1.241±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO (Soluble), Ethyl Acetate (Slightly)
form: Solid
pka: 5.45±0.10(Predicted)
color: Off-White to Pale Yellow
λmax: 219nm(MeOH)(lit.)
InChI: InChI=1S/C3H4N2O/c4-3-5-1-2-6-3/h1-2H,(H2,4,5)
InChIKey: ACTKAGSPIFDCMF-UHFFFAOYSA-N
SMILES: O1C=CN=C1N
CAS DataBase Reference: 4570-45-0(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 34-36/37/38
Safety Statements: 26-36/37/39-45-24/25
RIDADR: 2735
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 739731
Product name: 2-Aminooxazole
Purity: 97%
Packaging: 500mg
Price: $116
Updated: 2025/07/31

TCI Chemical

Product number: A2884
Product name: 2-Aminooxazole
Purity: >98.0%(GC)(T)
Packaging: 1g
Price: $128
Updated: 2024/03/01

TCI Chemical

Product number: A2884
Product name: 2-Aminooxazole
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $511
Updated: 2023/06/20

TRC

Product number: A618745
Product name: 2-Aminooxazole
Packaging: 100mg
Price: $50
Updated: 2021/12/16

TRC

Product number: A618745
Product name: 2-Aminooxazole
Packaging: 500mg
Price: $80
Updated: 2021/12/16

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Oxazole-2-amine Chemical Properties,Usage,Production

Uses

2-Aminooxazole is a chemical reagent used in the synthesis of novel inhibitors of the kinetoplastid Trypanosoma brucei.

Synthesis

420-04-2

141-46-8

4570-45-0

Example 2: Preparation of 2-aminooxazole. To a tetrahydrofuran (THF, 60 mL) solution of cyanamide (19.8 mL, 50% w/w aqueous solution, 0.25 mol) was added a 24 mL aqueous solution of 2-hydroxyacetaldehyde (15 g, 0.25 mol). The reaction mixture was treated with 2 M aqueous sodium hydroxide (25.2 mL, 0.05 mol) at 0 °C. The mixture was slowly warmed to room temperature and stirred continuously for 24 hours. Upon completion of the reaction, the volatile solvent (THF) was removed by distillation under reduced pressure. The remaining aqueous solution was extracted with ethyl acetate (4 × 200 mL). The organic phases were combined, dried with anhydrous sodium sulfate, and subsequently concentrated under reduced pressure to give 14.968 g (71.3% yield) of white solid product. The product was characterized by 400 MHz 1H NMR (CDCl3): δ 7.13 (s, 1H), 6.74 (s, 1H), 5.26 (br.s, 2H). Elemental analysis calculated values (C3H4N2O): C 42.86%, H 4.80%, N 33.32%; measured values: C 43.01%, H 4.87%, N 33.11%.

References

[1] Patent: WO2007/123892, 2007, A2. Location in patent: Page/Page column 50
[2] Patent: WO2004/110990, 2004, A2. Location in patent: Page 37
[3] Patent: WO2006/44869, 2006, A1. Location in patent: Page/Page column 132
[4] Chemistry - A European Journal, 2013, vol. 19, # 14, p. 4586 - 4595
[5] Synthesis, 1976, p. 591 - 593

Oxazole-2-amine Preparation Products And Raw materials

Raw materials

Sodium sulfate Tetrahydrofuran Diethyl ether Ethyl acetate Sodium hydroxide PETROLEUM ETHER Cyanamide GLYCOLALDEHYDE

Preparation Products

Idoxuridine

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Oxazole-2-amine Suppliers

Americas 1 Canada 1 China 151 Europe 1 Germany 2 India 3 Japan 1 United Kingdom 5 United States 26 Global 191

TCI Europe

Tel: 320-37350700
Fax: +32 (0)37350701
Email: sales@tcieurope.eu
Country: Europe
ProdList: 23671
Advantage: 75

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View Lastest Price from Oxazole-2-amine manufacturers

R&D Scientific Inc.

Product: Oxazole-2-amine 4570-45-0
Price: US $780.00/g
Min. Order: 1g
Purity: 97
Supply Ability: 500 Kg
Release date: 2024-02-23

Zhuozhou Wenxi import and Export Co., Ltd

Product: Oxazole-2-amine 4570-45-0
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: Oxazole-2-amine 4570-45-0
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

4570-45-0, Oxazole-2-amineRelated Search:

Triethanolamine Triallylamine Fenoxaprop-p-ethyl Acetaminophen Aminopyrine Oxazole Glucosamine Isoxazole Famoxadone Dibenzylamine Bis(2-ethylhexyl)amine Sulfamic acid Sulfamethoxazole Sulfisoxazole EC 2.6.1.2 Zoxazolamine 5-PHENYL-OXAZOL-2-YLAMINE 2-HYDRAZINO-1,3-BENZOXAZOLE

2-AMINO-OXAZOLE

1,3-OXAZOL-2-AMINE

2-Amino-1,3-oxazole

2-AMINOXAZOLE

OXAZOLE-2-YLAMINE

Oxazole-2-amine

OXAZOL-2-YLAMINE

oxazol-2-amine

2-Amino Oxazole Or 1,3-Oxazol-2-amine

2-OxazolaMine

2,3-dihydro-1,3-oxazol-2-amine

2-Aminooxazole &gt

2-Aminooxazole,97%

2-Oxazolamine (9CI, ACI)

4570-45-0

C3H4N20

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Oxazole