PluriSln 1
- Product Name
- PluriSln 1
- CAS No.
- 91396-88-2
- Chemical Name
- PluriSln 1
- Synonyms
- PluriSln;uriSIn 1;NSC 14613;PluriSIn#1;plurisln 1;PluriSIn PluriSIn;PluriSIn #1, >=98%;PluriSln 1 USP/EP/BP;NSC 14613, PluriSln 1;PluriSln 1, NSC 14613
- CBNumber
- CB82657004
- Molecular Formula
- C12H11N3O
- Formula Weight
- 213.24
- MOL File
- 91396-88-2.mol
PluriSln 1 Property
- Melting point:
- 177-178℃
- Boiling point:
- 335.7±15.0 °C(Predicted)
- Density
- 1.251±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- solubility
- DMSO: soluble15mg/mL, clear
- pka
- 10.69±0.23(Predicted)
- form
- powder
- color
- white to beige
- Stability:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H319Causes serious eye irritation
- Precautionary statements
-
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- I0975
- Product name
- PluriSIn 1
- Purity
- >98.0%(HPLC)
- Packaging
- 20mg
- Price
- $154
- Updated
- 2024/03/01
- Product number
- I0975
- Product name
- PluriSIn 1
- Purity
- >98.0%(HPLC)
- Packaging
- 100mg
- Price
- $460
- Updated
- 2024/03/01
- Product number
- 16161
- Product name
- PluriSln 1
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $62
- Updated
- 2024/03/01
- Product number
- 16161
- Product name
- PluriSln 1
- Purity
- ≥95%
- Packaging
- 10mg
- Price
- $109
- Updated
- 2024/03/01
- Product number
- 16161
- Product name
- PluriSln 1
- Purity
- ≥95%
- Packaging
- 25mg
- Price
- $211
- Updated
- 2024/03/01
PluriSln 1 Chemical Properties,Usage,Production
Description
PluriSln-1 (91396-88-2) is an inhibitor of stearoyl-coA desaturase (SCD1). PluriSln-1 was able to selectively eliminate human pluripotent stem cells (hPSCs) while not affecting a large array of progenitor and differentiated cells.1?The ability to eliminate potentially tumorigenic undifferentiated cells is important for increasing the safety of hPSC-based treatments. PluriSln-1 has been used to successfully eliminate tumorigenic cells in cardiomyocytes2?and chondrogenic cells3.
Uses
NSC 14613 is an inhibitor of the stearoyl-coA desaturase 1 (SCD1), which is able to selectively eliminate hPSCs.
storage
+4°C
References
1) Ben-David?et al. (2013),?Selective elimination of human pluripotent stem cells by an oleate synthesis inhibitor discovered in a high-throughput screen; Cell Stem Cell.?12?167 2) Zhang?et al. (2014),?Inhibition of stearoyl-coA desaturase eliminates tumorigenic Nanog-positive cells: improving the safety of iPS cell transplantation to myocardium; Cell Cycle?13?762 3) Cheng?et al. (2014),?Cartilage Repair Using Human Embryonic Stem Cell-Derived Chondroprogenitors; Stem Cells Transl. Med.?3?1287
PluriSln 1 Preparation Products And Raw materials
Raw materials
Preparation Products
PluriSln 1 Suppliers
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View Lastest Price from PluriSln 1 manufacturers
- Product
- 1,4-Pyridinecarboxylicacid 91396-88-2
- Price
- US $0.00-0.00/KG
- Min. Order
- 5mg
- Purity
- 99% HPLC
- Supply Ability
- 2000tons
- Release date
- 2019-12-30
- Product
- PluriSln 1 91396-88-2
- Price
- US $5.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1ton
- Release date
- 2019-09-03