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5-Bromo-2-methylbenzoic acid

Product Name
5-Bromo-2-methylbenzoic acid
CAS No.
79669-49-1
Chemical Name
5-Bromo-2-methylbenzoic acid
Synonyms
5-Bromo-o-toluic acid;2-METHYL-5-BROMOBENZOIC ACID;5-Bromo-o-toluicacid(COOH=1);5-BROMO-2-METHYLBENZOIC ACID;Benzoic acid, 5-bromo-2-methyl-;5-Bromo-2-methylbenzoic acid 97%;5-BROMO-2-METHYLBENZOIC ACID,98%;5-Bromo-2-methylbenzoic Acid >5-Bromo-2-methylbenzoic acid ,97%;5 - BROMO - 2 - METHYL BENZEIC ACID
CBNumber
CB8266620
Molecular Formula
C8H7BrO2
Formula Weight
215.04
MOL File
79669-49-1.mol
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5-Bromo-2-methylbenzoic acid Property

Melting point:
167-171°C
Boiling point:
319.4±30.0 °C(Predicted)
Density 
1.599±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
soluble in Methanol
form 
powder to crystal
pka
3.48±0.25(Predicted)
color 
White to Almost white
InChIKey
SEENCYZQHCUTSB-UHFFFAOYSA-N
CAS DataBase Reference
79669-49-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
22-36/37/38
Safety Statements 
26
RIDADR 
UN 2811 6.1/PG 3
WGK Germany 
3
HazardClass 
IRRITANT
PackingGroup 
HS Code 
29163990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
694797
Product name
5-Bromo-2-methylbenzoic acid
Purity
97%
Packaging
1g
Price
$24
Updated
2023/06/20
Sigma-Aldrich
Product number
694797
Product name
5-Bromo-2-methylbenzoic acid
Purity
97%
Packaging
5g
Price
$67.5
Updated
2023/06/20
TCI Chemical
Product number
B3050
Product name
5-Bromo-2-methylbenzoic Acid
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$25
Updated
2024/03/01
TCI Chemical
Product number
B3050
Product name
5-Bromo-2-methylbenzoic Acid
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$50
Updated
2024/03/01
Alfa Aesar
Product number
H60516
Product name
5-Bromo-2-methylbenzoic acid, 97%
Packaging
5g
Price
$99.65
Updated
2024/03/01
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5-Bromo-2-methylbenzoic acid Chemical Properties,Usage,Production

Chemical Properties

Off-white Powder.

Uses

2-Methyl-5-bromobenzoic acid is used in organic synthesis and pharmaceutical intermediates. It is used in the synthesis of 5-bromo-2-methyl-N-(quinolin-8-yl)benzamide, (5-Bromo-2-methylphenyl)(thiophen-2-yl)-methanone and 2-(5-bromo-2-methylbenzyl)-5-(4-fluorophenyl)thiophene.

Synthesis

In a reaction vessel equipped with a mechanical stirrer, a solution of 2-methylbenzoic acid (10.00 g, 73.45 mmol, 1.0 equivalent) in concentrated sulfuric acid (15 mL) at room temperature, bromine (17.6 g, 110.14 mmol, 1. 5 equivalents) was added dropwise over 10 minutes and stirred at 25 ° C. for 20 hours. The reaction solution was injected into ice water (60 ml), and the precipitated solid was filtered, washed with water (20 mL), and air-dried at 60 ° C. overnight to obtain a bromo compound (15.2 g, 97%, addition rate: 95.7).5-Br body / 3-Br body = 62: 38). The obtained crude bromo compound (3 g) was dissolved in ethanol (9 mL) at 70 ° C., cooled to 20 ° C., and stirred at the same temperature for 30 minutes at 10 ° C. or lower for 3 hours. The precipitated crystals were filtered and air-dried at 60 ° C. overnight to obtain 5-Bromo-2-methylbenzoic acid(1.19 g, 5-Br / 3-Br = 91: 9, total yield: 38.5%).

5-Bromo-2-methylbenzoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Bromo-2-methylbenzoic acid Suppliers

Alkemi BVBA
Tel
--
Fax
--
Email
nfo@alkemi.be
Country
Belgium
ProdList
2201
Advantage
58
TCI EUROPE N.V.
Tel
--
Fax
--
Email
sales@tcieurope.be
Country
Belgium
ProdList
2200
Advantage
66
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View Lastest Price from 5-Bromo-2-methylbenzoic acid manufacturers

airuikechemical co., ltd.
Product
2-METHYL-5-BROMOBENZOIC ACID 79669-49-1
Price
US $0.00-0.00/g
Min. Order
1g
Purity
99.99%
Supply Ability
20 tons
Release date
2024-04-07
Hebei Weibang Biotechnology Co., Ltd
Product
5-Bromo-2-methylbenzoic acid 79669-49-1
Price
US $1.00/PCS
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2021-07-14
Hebei Mojin Biotechnology Co., Ltd
Product
5-Bromo-2-methylbenzoic acid 79669-49-1
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-08-21

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  • Aromatic Nitriles
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