ChemicalBook > CAS DataBase List > 4-Bromo-3-nitrobenzoic acid

4-Bromo-3-nitrobenzoic acid

Product Name
4-Bromo-3-nitrobenzoic acid
CAS No.
6319-40-0
Chemical Name
4-Bromo-3-nitrobenzoic acid
Synonyms
RARECHEM AH CK 0042;4-Bromo-3-nitrobenzoicaci;4-BROMO-3-NITROBENZOIC ACID;3-Nitro-4-bromobenzoic acid;2-Bromo-5-carboxynitrobenzene;Benzoic acid, 4-bromo-3-nitro-;4-Bromo-3-nitrobenzoic Acid >4-BROMO-3-NITRO-BENZOIC ACID >97%;4-Bromo-3-nitrobenzoic acid, 95%,;4-Bromo-3-nitrobenzoic acid ISO 9001：2015 REACH
CBNumber
CB8271789
Molecular Formula
C7H4BrNO4
Formula Weight
246.01
MOL File
6319-40-0.mol
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4-Bromo-3-nitrobenzoic acid Property

Melting point:
202-204°C
Boiling point:
340.9±32.0 °C(Predicted)
Density 
2.0176 (rough estimate)
refractive index 
1.6200 (estimate)
storage temp. 
2-8°C
solubility 
soluble in Methanol
form 
Solid
pka
3.35±0.10(Predicted)
color 
White to yellow
CAS DataBase Reference
6319-40-0(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-22
Safety Statements 
26-36/37/39
WGK Germany 
3
Hazard Note 
Irritant
HS Code 
29163990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
724734
Product name
4-Bromo-3-nitrobenzoic acid
Purity
95%
Packaging
5g
Price
$24
Updated
2023/06/20
TCI Chemical
Product number
B3689
Product name
4-Bromo-3-nitrobenzoic Acid
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$67
Updated
2025/07/31
TCI Chemical
Product number
B3689
Product name
4-Bromo-3-nitrobenzoic Acid
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$265
Updated
2025/07/31
TRC
Product number
B697958
Product name
4-Bromo-3-nitrobenzoic Acid
Packaging
500mg
Price
$65
Updated
2021/12/16
TRC
Product number
B697958
Product name
4-Bromo-3-nitrobenzoic Acid
Packaging
250mg
Price
$55
Updated
2021/12/16
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4-Bromo-3-nitrobenzoic acid Chemical Properties,Usage,Production

Chemical Properties

light yellow powder

Synthesis

586-76-5

6319-40-0

The general procedure for the synthesis of 4-bromo-3-nitrobenzoic acid from 4-bromobenzoic acid is as follows: 1. prepare a nitration mixture by slowly adding fuming nitric acid (12.4 mL, 0.3 mol) to concentrated hydrochloric acid followed by sulfuric acid (30.1 mL, 0.6 mol) at 0-5 °C. 2. the cooled nitrification mixture was transferred to a beaker fitted with a mechanical stirrer and a charging funnel. 3. 4-Bromobenzoic acid (40 g, 0.2 mol) was slowly added to the nitrification mixture in batches while maintaining a temperature of 0-5°C. The dosing process lasted for 5 hours. 4. After completion of the addition, the reaction mixture was continued to be stirred at room temperature for 2 hours. 5. The reaction mixture was slowly poured into ice water to precipitate the solid product. 6. The solid product was separated by filtration, washed with water to neutrality and subsequently air dried to constant weight to give the pure 4-bromo-3-nitrobenzoic acid (white solid, 47.2 g, 96% yield). Product characterization data: 1H NMR (300 MHz, CDCl3): δ 7.85 (d, J = 12.0 Hz, 1H), 8.09 (d, J = 12.0 Hz, 1H), 8.48 (s, 1H). 13C NMR (75 MHz, CDCl3): δ 124.2, 132.1, 135.2, 138.0, 139.8, 159.8, 171.0.

References

[1] Beilstein Journal of Organic Chemistry, 2016, vol. 12, p. 2267 - 2273
[2] Patent: US2008/293736, 2008, A1. Location in patent: Page/Page column 32
[3] Patent: WO2017/7634, 2017, A1. Location in patent: Paragraph 0730; 0731; 0732
[4] Patent: WO2005/16882, 2005, A1. Location in patent: Page/Page column 13
[5] Justus Liebigs Annalen der Chemie, 1884, vol. 222, p. 178 Anm. 1

4-Bromo-3-nitrobenzoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 4-Bromo-3-nitrobenzoic acid manufacturers

Henan Fengda Chemical Co., Ltd
Product
4-Bromo-3-nitrobenzoic acid 6319-40-0
Price
US $100.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-25
Career Henan Chemical Co
Product
4-Bromo-3-nitrobenzoic acid 6319-40-0
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1kg;10kg;100kg
Release date
2019-08-29

6319-40-0, 4-Bromo-3-nitrobenzoic acidRelated Search:

4-BROMO-3-NITRO-BENZALDEHYDE 4-Bromo-3-nitrobenzoic acid Methyl 4-bromo-3-nitrobenzoate METHYL 2-BROMO-5-NITROBENZOIC ACID,2-BROMO-5-NITROBENZOIC ACID METHYL ESTER Methyl 3-bromo-5-nitrobenzoate 2-BROMO-5-NITROBENZOIC ACID 3-BROMO-4-NITROBENZOIC ACID 97 5-BROMO-2-NITRO-BENZOIC ACID 2-Bromo-4-nitrobenzoic acid 98% tert-Butyl 4-bromo-2-nitrobenzoate Ethyl 3-bromo-5-nitrobenzoate 4-BROMO-2-NITROBENZOIC ACID,4-Bromo-2-Nitrobenzoic Acid 2-Nitro-4-Bromobenzoic Acid METHYL 2-BROMO-4-NITROBENZOATE Ethyl 2-bromo-3-nitrobenzoate 2-BROMO-3-NITROBENZOIC ACID (KG LEVEL),2-BROMO-3-NITROBENZOIC ACID, TECH., 90%,2-Bromo-3-nitrobenzoic acid 95%,2-BROMO-3-NITROBENZOIC ACID 3-BROMO-5-NITROBENZOIC ACID 2-amino-5-bromo-3-nitrobenzoic acid 3-Nitrobenzoic acid

  • RARECHEM AH CK 0042
  • 4-BROMO-3-NITROBENZOIC ACID
  • 4-BROMO-3-NITRO-BENZOIC ACID >97%
  • 3-Nitro-4-bromobenzoic acid
  • 2-Bromo-5-carboxynitrobenzene
  • 4-Bromo-3-nitrobenzoic Acid &gt
  • Benzoic acid, 4-bromo-3-nitro-
  • 4-Bromo-3-nitrobenzoicaci
  • 4-Bromo-3-nitrobenzoic acid ISO 9001：2015 REACH
  • 4-Bromo-3-nitrobenzoic acid, 95%,
  • 6319-40-0
  • 6319-40-4
  • intermediate
  • Benzoic acid
  • blocks
  • Bromides
  • Carboxes
  • NitroCompounds
  • Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts