CYCLO(-HIS-PRO)
- Product Name
- CYCLO(-HIS-PRO)
- CAS No.
- 53109-32-3
- Chemical Name
- CYCLO(-HIS-PRO)
- Synonyms
- Cyclo(HP);Cyclo(Pro-His);CYCLO(-HIS-PRO);HIS-PRO, CYCLIC;Cyclo-Pro-His-HO;CYCLO(HIS-PRO), >99%;Cyclo(histidyl-proline);Protirelin EP Impurity E;Cyclo(L-histidyl-L-proline);Nebivolol Impurity 10 Monomer
- CBNumber
- CB8279260
- Molecular Formula
- C11H14N4O2
- Formula Weight
- 234.25
- MOL File
- 53109-32-3.mol
CYCLO(-HIS-PRO) Property
- Melting point:
- 162-164 °C
- Boiling point:
- 659.3±48.0 °C(Predicted)
- Density
- 1.41±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMF: 1 mg/ml; DMSO: 1 mg/ml; Ethanol: 1 mg/ml; PBS (pH 7.2): 1 mg/ml
- form
- A neat oil
- pka
- 12.73±0.40(Predicted)
Safety
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- FC49257
- Product name
- Cyclo(L-His-L-Pro)
- Packaging
- 25mg
- Price
- $83.5
- Updated
- 2021/12/16
- Product number
- CS-6320
- Product name
- Cyclo(his-pro)
- Packaging
- 5mg
- Price
- $90
- Updated
- 2021/12/16
- Product number
- FC49257
- Product name
- Cyclo(L-His-L-Pro)
- Packaging
- 50mg
- Price
- $140.5
- Updated
- 2021/12/16
- Product number
- CS-6320
- Product name
- Cyclo(his-pro)
- Packaging
- 10mg
- Price
- $150
- Updated
- 2021/12/16
- Product number
- FC49257
- Product name
- Cyclo(L-His-L-Pro)
- Packaging
- 100mg
- Price
- $225
- Updated
- 2021/12/16
CYCLO(-HIS-PRO) Chemical Properties,Usage,Production
Uses
Cyclo(L-histidyl-L-proline) is used in the pharmaceutical composition comprising cyclo(His-Pro) for preventing or treating obesity.
Definition
ChEBI: Cyclo(L-His-L-Pro) is a homodetic cyclic peptide resulting from the formal condensation of both the amino and acid groups of L-histidine with the acid and amino groups of L-proline. It is a metabolite of thyrotropin-releasing hormone (TRH). It has a role as a human blood serum metabolite, a dopamine uptake inhibitor and an anti-inflammatory agent. It is a homodetic cyclic peptide, a dipeptide, a pyrrolopyrazine and a member of imidazoles. It is functionally related to a L-histidine and a L-proline.
CYCLO(-HIS-PRO) Preparation Products And Raw materials
Raw materials
Preparation Products
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