ChemicalBook > CAS DataBase List > Ethyl 3-bromopropionate
Ethyl 3-bromopropionate
- Product Name
- Ethyl 3-bromopropionate
- CAS No.
- 539-74-2
- Chemical Name
- Ethyl 3-bromopropionate
- Synonyms
- Ethyl 3-bromopropanoate;Propionic acid, 3-bromo-, ethyl ester;3-ethyl broMide;3-broMo-propanoate;Ethyl 3-bromopropion;Ethyl-bromopropionate;*Tramadol Impurity 11;Ethyl3-Bromopropanoate;ETHYL 3-BROMOPROPIONATE;Ethyl Acetate Impurity 9
- CBNumber
- CB8298638
- Molecular Formula
- C5H9BrO2
- Formula Weight
- 181.03
- MOL File
- 539-74-2.mol
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Ethyl 3-bromopropionate Property
- Melting point:
- 184-186 °C(Solv: water (7732-18-5))
- Boiling point:
- 135-136 °C/50 mmHg (lit.)
- Density
- 1.412 g/mL at 25 °C (lit.)
- refractive index
- n20/D 1.452(lit.)
- Flash point:
- 175 °F
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- H2O: soluble
- form
- Liquid
- color
- Clear colorless to pale yellow
- Water Solubility
- Soluble in water, alcohol, chloroform, benzene.
- Sensitive
- Light Sensitive
- BRN
- 1700933
- Dielectric constant
- 9.4（20.0℃）
- CAS DataBase Reference
- 539-74-2(CAS DataBase Reference)
- NIST Chemistry Reference
- Propanoic acid, 3-bromo-, ethyl ester(539-74-2)
- EPA Substance Registry System
- Propanoic acid, 3-bromo-, ethyl ester (539-74-2)
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 128163
- Product name
- Ethyl 3-bromopropionate
- Purity
- 98%
- Packaging
- 25g
- Price
- $78.1
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- 128163
- Product name
- Ethyl 3-bromopropionate
- Purity
- 98%
- Packaging
- 100g
- Price
- $103
- Updated
- 2025/07/31
TCI Chemical
- Product number
- B0647
- Product name
- Ethyl 3-Bromopropionate
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $68
- Updated
- 2025/07/31
TCI Chemical
- Product number
- B0647
- Product name
- Ethyl 3-Bromopropionate
- Purity
- >98.0%(GC)
- Packaging
- 100g
- Price
- $182
- Updated
- 2025/07/31
TCI Chemical
- Product number
- B0647
- Product name
- Ethyl 3-Bromopropionate
- Purity
- >98.0%(GC)
- Packaging
- 500g
- Price
- $726
- Updated
- 2025/07/31
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Ethyl 3-bromopropionate Chemical Properties,Usage,Production
Chemical Properties
clear colorless to pale yellow liquid
Uses
Ethyl 3-bromopropionate was used in the preparation of (3?,4?-dimethoxyphenyl)-5-oxopentanoic acid.
Application
Ethyl 3-bromopropionate is primarily used as an intermediate in organic synthesis. Due to the presence of an active bromine atom in its molecular structure, it exhibits the properties of an alkylating agent in chemical reactions, enabling it to participate in various types of chemical reactions. It is an important electrophilic reagent that can be used to introduce specific functional groups or carbon chains when constructing complex organic molecules.
Synthesis
The amount of 3-bromopropionic acid was fixed at 30 g. Ethanol and 3-bromopropionic acid were added to a 100 mL three-necked round-bottom flask at a molar ratio of 1.5, followed by 60 mL of benzene and 1.2 g of p-toluenesulfonic acid. The mixture was thoroughly shaken, and a condenser and water separator were connected. The mixture was refluxed at 80 °C for 3.5 h until no more water precipitated. The solvent was evaporated, 20 mL of 5% sodium bicarbonate solution was added, and the mixture was washed with 50 mL of water. The mixture was then redistilled. Ethyl 3-bromopropionate was obtained with a mass fraction of 98.49% and a yield of 94.7%.
References
[1] Patent: US2009/156593, 2009, A1. Location in patent: Page/Page column 10
[2] Journal of the American Chemical Society, 1934, vol. 56, p. 698
[3] Org.Synth. Coll.Vol.III<1955>577,
[4] Annales de Chimie (Cachan, France), 1921, vol. <9>15, p. 246
[5] Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1921, vol. 172, p. 1269
Ethyl 3-bromopropionate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Ethyl 3-bromopropionate manufacturers
Shandong Vital Biotechnology Co., Ltd.
- Product
- Ethyl 3-bromopropionate 539-74-2
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 100tons
- Release date
- 2025-11-20
Shaanxi Dideu New Materials Co. Ltd
- Product
- Ethyl 3-bromopropionate 539-74-2
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2025-02-20
Henan Fengda Chemical Co., Ltd
- Product
- Ethyl 3-bromopropionate 539-74-2
- Price
- US $8.00-0.80/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-09
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