ChemicalBook > CAS DataBase List > Tos-PEG4-CH2CO2H
Tos-PEG4-CH2CO2H
- Product Name
- Tos-PEG4-CH2CO2H
- CAS No.
- 1581248-63-6
- Chemical Name
- Tos-PEG4-CH2CO2H
- Synonyms
- Tos-PEG3-CH2COOH;Tos-PEG4-CH2CO2H;2-[2-[2-[2-(Tosyloxy)ethoxy]ethoxy]ethoxy]acetic Acid;2-[2-[2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethoxy]ethoxy]acetic acid;2-[2-(2-{2-[(4-methylbenzenesulfonyl)oxy]ethoxy}ethoxy)ethoxy]acetic acid;Acetic acid, 2-[2-[2-[2-[[(4-methylphenyl)sulfonyl]oxy]ethoxy]ethoxy]ethoxy]-
- CBNumber
- CB83062689
- Molecular Formula
- C15H22O8S
- Formula Weight
- 362.4
- MOL File
- 1581248-63-6.mol
More
Less
Tos-PEG4-CH2CO2H Property
- Boiling point:
- 539.9±45.0 °C(Predicted)
- Density
- 1.280±0.06 g/cm3(Predicted)
- solubility
- Soluble in DCM
- pka
- 3.39±0.10(Predicted)
More
Less
N-Bromosuccinimide Price
BroadPharm
- Product number
- BP-22089
- Product name
- Tos-PEG4-CH2CO2H
- Purity
- 98%
- Packaging
- 250mg
- Price
- $290
- Updated
- 2021/12/16
BroadPharm
- Product number
- BP-22089
- Product name
- Tos-PEG4-CH2CO2H
- Purity
- 98%
- Packaging
- 500mg
- Price
- $485
- Updated
- 2021/12/16
BroadPharm
- Product number
- BP-22089
- Product name
- Tos-PEG4-CH2CO2H
- Purity
- 98%
- Packaging
- 1g
- Price
- $680
- Updated
- 2021/12/16
More
Less
Tos-PEG4-CH2CO2H Chemical Properties,Usage,Production
Description
Tos-PEG4-CH2CO2H is a PEG linker containing a tosyl group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The tosyl group is a very good leaving group for nucleophilic substitution reactions. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.
Uses
Tos-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34. DOI:10.1038/s12276-018-0065-6
Tos-PEG4-CH2CO2H Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
Tos-PEG4-CH2CO2H Suppliers
- Tel
- --
- Fax
- --
- sales@apolloscientific.co.uk
- Country
- United Kingdom
- ProdList
- 6084
- Advantage
- 88
1581248-63-6, Tos-PEG4-CH2CO2HRelated Search:
Tos-PEG4-acid
Tos-PEG5 t-butyl ester
Tos-PEG2-CH2CO2tBu
Tos-PEG2-t-butyl ester
Tos-PEG4-t-butyl ester
Tos-PEG6-t-Butyl ester
Tos-PEG3-CH2CO2tBu
Tos-PEG5-CH2CO2H
Tos-PEG5-CH2CO2t-butyl ester
Tos-PEG3-CH2CO2H