Tos-PEG7-CH2CO2t-butyl ester
- Product Name
- Tos-PEG7-CH2CO2t-butyl ester
- CAS No.
- 1530777-90-2
- Chemical Name
- Tos-PEG7-CH2CO2t-butyl ester
- Synonyms
- Tos-PEG6-CH2-Boc;Tos-PEG6-CH2COOtBu;Tos-PEG7-CH2CO2tBu;Tos-PEG7-t-butyl acetate;Tos-PEG7-CH2CO2t-butyl ester;tert-butyl 20-(tosyloxy)-3,6,9,12,15,18-hexaoxaicosanoate;tert-Butyl 20-(Tosyloxy)-3,6,9,12,15,18-hexaoxaicosan-1-oate;3,6,9,12,15,18-Hexaoxaeicosanoic acid, 20-[[(4-methylphenyl)sulfonyl]oxy]-, 1,1-dimethylethyl ester;Tos-PEG6-CH2COOtBu/3,6,9,12,15,18-Hexaoxaeicosanoic acid, 20-[[(4-methylphenyl)sulfonyl]oxy]-, 1,1-dimethylethyl ester
- CBNumber
- CB83062694
- Molecular Formula
- C25H42O11S
- Formula Weight
- 550.66
- MOL File
- 1530777-90-2.mol
Tos-PEG7-CH2CO2t-butyl ester Property
- storage temp.
- Storage temp. 2-8°C
- form
- Viscous Liquid
- color
- Colorless to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- BP-22131
- Product name
- Tos-PEG7-CH2CO2tBu
- Purity
- 98%
- Packaging
- 250mg
- Price
- $360
- Updated
- 2021/12/16
- Product number
- AS104145
- Product name
- Tos-PEG6-CH2COOtBu
- Purity
- 95+%
- Packaging
- 1g
- Price
- $588
- Updated
- 2021/12/16
- Product number
- BIPG1861
- Product name
- Tos-PEG7-CH2CO2t-butyl ester
- Packaging
- 250mg
- Price
- $701
- Updated
- 2021/12/16
- Product number
- BP-22131
- Product name
- Tos-PEG7-CH2CO2tBu
- Purity
- 98%
- Packaging
- 1g
- Price
- $880
- Updated
- 2021/12/16
- Product number
- B-1086
- Product name
- Tos-PEG6-CH2COOtBu
- Purity
- 97%
- Packaging
- 0.25g
- Price
- $220
- Updated
- 2021/12/16
Tos-PEG7-CH2CO2t-butyl ester Chemical Properties,Usage,Production
Description
Tos-PEG7-CH2CO2tBu is a PEG linker containing a t-butyl ester and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The tosyl group is a very good leaving group for nucleophilic substitution reactions.
Uses
Tos-PEG6-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs; Alkyl/ether
References
[1] Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34. DOI:10.1038/s12276-018-0065-6
Tos-PEG7-CH2CO2t-butyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
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