ChemicalBook > CAS DataBase List > O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE
O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE
- Product Name
- O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE
- CAS No.
- 57981-02-9
- Chemical Name
- O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE
- Synonyms
- PFBHA;O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine;PFBHA HCL;Nsc153392;FLOROX REAGENT;FLOROX(TM) REAGENT;TIMTEC-BB SBB003152;Pentafluorobenzylhydroxylamine;PENTAFLUOROBENZYLHYDROXYLAMINE HCL;(2,3,4,5,6-Pentafluorobenzyl)oxyamine
- CBNumber
- CB8307815
- Molecular Formula
- C7H5ClF5NO
- Formula Weight
- 249.57
- MOL File
- 57981-02-9.mol
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O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE Property
- Melting point:
- 227 °C (subl.)(lit.)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- H2O: 5%, clear
- form
- powder to crystal
- color
- White
- PH
- pH(5g/l, 25℃) : 2.0～3.0
- Water Solubility
- Soluble in water.
- BRN
- 4031190
- CAS DataBase Reference
- 57981-02-9(CAS DataBase Reference)
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 194484
- Product name
- O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride
- Purity
- ≥98%
- Packaging
- 250mg
- Price
- $58.7
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 194484
- Product name
- O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride
- Purity
- ≥98%
- Packaging
- 1g
- Price
- $159
- Updated
- 2024/03/01
TCI Chemical
- Product number
- P0822
- Product name
- O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine Hydrochloride [for Oxime Preparation]
- Purity
- >98.0%(HPLC)(N)
- Packaging
- 1g
- Price
- $123
- Updated
- 2024/03/01
TCI Chemical
- Product number
- P0822
- Product name
- O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine Hydrochloride [for Oxime Preparation]
- Purity
- >98.0%(HPLC)(N)
- Packaging
- 5g
- Price
- $465
- Updated
- 2024/03/01
Alfa Aesar
- Product number
- A18368
- Product name
- O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride, 99+%
- Packaging
- 0.25g
- Price
- $53.65
- Updated
- 2024/03/01
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O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE Chemical Properties,Usage,Production
Chemical Properties
White powder
Uses
O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride is used in the preparation of oximes of steroids having keto group. It is used as a derivatization reagent in the determination of thromboxane B2, prostaglandins, amygdalin and a variety of aldehydes, ketones and acids. It is a versatile reagent utilized for the detection of carbonyl-containing compounds by gas chromatography (GC), gas chromatography mass spectrometry (GC-MS) and other methods. As a derivatization reagent, it is also used for EC/LC analysis of keto-steroids and carbohydrates.
Uses
PFBHA.HCl has been used for derivatization of metabolites with carbonyl groups followed by analysis via GC-MS. It has also been used in aldehyde derivatization followed by aldehydic hydrolysis using GC/MS.
Uses
O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride is used:
- In the preparation of oximes of steroids-bearing keto group.
- As a derivatization reagent in the determination of thromboxane B2, prostaglandins, amygdalin, and a variety of aldehydes, ketones, and acids.
General Description
O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride (PFBHA.HCl) is a derivatizing agent.
Purification Methods
Recrystallise the salt from EtOH to form colourless leaflets. Drying the compound at high vacuum and elevated temperature will result in losses by sublimation. [Youngdale J Pharm Sci 65 625 1976, Wehner & Handke J Chromatog 177 237 1979, Nambara et al. give incorrect m as 115-116o J Chromatogr 114 81 1975.]
O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Hexane
Hydrazinium hydroxide solution
N-Hydroxyphthalimide
N,N-Dimethylformamide
Acetone
Bromopentafluorobenzene
Triethylamine
Hydrogen bromide
Tetrahydrofuran
Diethyl ether
Lithium Aluminum Hydride
Hydrochloric acid
Dichloromethane
Methanol
Sodium hydroxide
Magnesium
N-Methylformanilide
Sulfuric acid
Preparation Products
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O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE Suppliers
- Tel
- --
- Fax
- --
- info@pschemicals.com
- Country
- The Netherlands
- ProdList
- 2724
- Advantage
- 58
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View Lastest Price from O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE manufacturers
Career Henan Chemical Co
- Product
- O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE 57981-02-9
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2018-12-20
57981-02-9, O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDERelated Search:
2,3,4,5-Tetrafluorobenzyl alcohol
2,3,4,5,6-PENTAFLUOROTOLUENE
2,6-Difluorobenzyl alcohol
2,3-Difluorobenzyl alcohol
2,3,5-Trifluorobenzyl alcohol
2,3,4,6-TETRAFLUOROBENZYL ALCOHOL
Methoxyammonium chloride
2,4-Difluorobenzyl alcohol
3,4,5-Trifluorobenzenemethanol
3,5-Difluorobenzyl alcohol
Ethoxyamine hydrochloride
2,3,6-TRIFLUOROBENZYL ALCOHOL
2,5-Difluorobenzyl alcohol
3,4-Difluorobenzyl alcohol
2,3,4-Trifluorobenzyl alcohol
O-Benzylhydroxylamine hydrochloride
2,3,4,5,6-Pentafluorobenzyl alcohol
1,2,3,5-Tetrafluorobenzene