ChemicalBook > CAS DataBase List > O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE

O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE

Product Name
O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE
CAS No.
57981-02-9
Chemical Name
O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE
Synonyms
PFBHA;O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine;PFBHA HCL;Nsc153392;FLOROX REAGENT;FLOROX(TM) REAGENT;TIMTEC-BB SBB003152;Pentafluorobenzylhydroxylamine;PENTAFLUOROBENZYLHYDROXYLAMINE HCL;(2,3,4,5,6-Pentafluorobenzyl)oxyamine
CBNumber
CB8307815
Molecular Formula
C7H5ClF5NO
Formula Weight
249.57
MOL File
57981-02-9.mol
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O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE Property

Melting point:
227 °C (subl.)(lit.)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
H2O: 5%, clear
form 
powder to crystal
color 
White
PH
pH(5g/l, 25℃) : 2.0～3.0
Water Solubility 
Soluble in water.
BRN 
4031190
CAS DataBase Reference
57981-02-9(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-24/25
WGK Germany 
3
F 
10
HazardClass 
IRRITANT
HS Code 
29280000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
194484
Product name
O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride
Purity
≥98%
Packaging
250mg
Price
$58.7
Updated
2024/03/01
Sigma-Aldrich
Product number
194484
Product name
O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride
Purity
≥98%
Packaging
1g
Price
$159
Updated
2024/03/01
TCI Chemical
Product number
P0822
Product name
O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine Hydrochloride [for Oxime Preparation]
Purity
>98.0%(HPLC)(N)
Packaging
1g
Price
$123
Updated
2024/03/01
TCI Chemical
Product number
P0822
Product name
O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine Hydrochloride [for Oxime Preparation]
Purity
>98.0%(HPLC)(N)
Packaging
5g
Price
$465
Updated
2024/03/01
Alfa Aesar
Product number
A18368
Product name
O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride, 99+%
Packaging
0.25g
Price
$53.65
Updated
2024/03/01
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O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride is used in the preparation of oximes of steroids having keto group. It is used as a derivatization reagent in the determination of thromboxane B2, prostaglandins, amygdalin and a variety of aldehydes, ketones and acids. It is a versatile reagent utilized for the detection of carbonyl-containing compounds by gas chromatography (GC), gas chromatography mass spectrometry (GC-MS) and other methods. As a derivatization reagent, it is also used for EC/LC analysis of keto-steroids and carbohydrates.

Uses

PFBHA.HCl has been used for derivatization of metabolites with carbonyl groups followed by analysis via GC-MS. It has also been used in aldehyde derivatization followed by aldehydic hydrolysis using GC/MS.

Uses

O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride is used:

  • In the preparation of oximes of steroids-bearing keto group.
  • As a derivatization reagent in the determination of thromboxane B2, prostaglandins, amygdalin, and a variety of aldehydes, ketones, and acids.
It is a versatile reagent used for the detection of carbonyl-containing compounds by GC, GC-MS, and other methods.

General Description

O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride (PFBHA.HCl) is a derivatizing agent.

Purification Methods

Recrystallise the salt from EtOH to form colourless leaflets. Drying the compound at high vacuum and elevated temperature will result in losses by sublimation. [Youngdale J Pharm Sci 65 625 1976, Wehner & Handke J Chromatog 177 237 1979, Nambara et al. give incorrect m as 115-116o J Chromatogr 114 81 1975.]

O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Hexane Hydrazinium hydroxide solution N-Hydroxyphthalimide N,N-Dimethylformamide Acetone Bromopentafluorobenzene Triethylamine Hydrogen bromide Tetrahydrofuran Diethyl ether Lithium Aluminum Hydride Hydrochloric acid Dichloromethane Methanol Sodium hydroxide Magnesium N-Methylformanilide Sulfuric acid

Preparation Products

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O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE Suppliers

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View Lastest Price from O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE manufacturers

Career Henan Chemical Co
Product
O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE 57981-02-9
Price
US $1.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
100KG
Release date
2018-12-20

57981-02-9, O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDERelated Search:

2,3,4,5-Tetrafluorobenzyl alcohol 2,3,4,5,6-PENTAFLUOROTOLUENE 2,6-Difluorobenzyl alcohol 2,3-Difluorobenzyl alcohol 2,3,5-Trifluorobenzyl alcohol 2,3,4,6-TETRAFLUOROBENZYL ALCOHOL Methoxyammonium chloride 2,4-Difluorobenzyl alcohol 3,4,5-Trifluorobenzenemethanol 3,5-Difluorobenzyl alcohol Ethoxyamine hydrochloride 2,3,6-TRIFLUOROBENZYL ALCOHOL 2,5-Difluorobenzyl alcohol 3,4-Difluorobenzyl alcohol 2,3,4-Trifluorobenzyl alcohol O-Benzylhydroxylamine hydrochloride 2,3,4,5,6-Pentafluorobenzyl alcohol 1,2,3,5-Tetrafluorobenzene

  • 2-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE
  • FLOROX REAGENT
  • FLOROX(TM) REAGENT
  • PFBHA
  • PFBHA HCL
  • PENTAFLUOROBENZYLHYDROXYLAMINE HCL
  • O-(PENTAFLUOROBENZYL)HYDROXYAMINE HYDROCHLORIDE
  • O-(PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE
  • O-PENTAFLUOROBENZYLHYDROXYLAMINE HYDROCHLORIDE IN PYRIDINE
  • O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE
  • TIMTEC-BB SBB003152
  • 0-(2,3,4,5,6-Pentafluorobenzyl) Hydroxylamine Hydrochloride
  • O-(Pentafluorobenzyl)hydroxylamine hydrochloride 97%
  • O-(2,3,4,5,6-pentafluorobenzyl)*hydroxylamine hyd
  • O-(2,3,4,5,6-PENTAFLUOROBENZYL)HYDROXYL- AMINE HYDROCHLORIDE, 99+%
  • O-(2,3,4,5,6-PENTAFLUOROBENZYL)*HYDROXYL AMINE HYDRO
  • O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamineHCl
  • O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride 97%
  • O-(Pentafluorobenzyl)hydroxylaminehydrochloride97%
  • O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine Hydrochloride [for Oxime Preparation]
  • (2,3,4,5,6-Pentafluorobenzyl)oxyamine
  • [(2,3,4,5,6-Pentafluorobenzyl)oxy]amine
  • O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine
  • O-(Pentafluorophenylmethyl)hydroxylamine
  • Pentafluorobenzylhydroxylamine
  • O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine·hydrochloric acid
  • Pentafluorobenzylhydroxylamine·hydrochloride
  • 1-[(Aminooxy)methyl]-2,3,4,5,6-pentafluorobenzene hydrochloride
  • 2,3,4,5,6-Pentafluorobenzyloxyamine hydrochloride
  • N-[(2,3,4,5,6-Pentafluorobenzyl)oxy]amine hydrochloride
  • Nsc153392
  • O-[(2,3,4,5,6-Pentafluorophenyl)methyl]hydroxylamine hydrochloride
  • O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylaMine hydrochloride >=98%
  • O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylaMine hydrochloride, derivatization grade
  • Hydroxylamine, O-[(2,3,4,5,6-pentafluorophenyl)methyl]-, hydrochloride (1:1)
  • 6-PENTAFLUOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE
  • O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride, 99%, derivatization grade
  • Method 556 PFBHA Reagent@15.0 mg/mL in Water
  • O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamineHydrochloride[forOximePreparation]&gt
  • O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride for GC derivatization
  • O-[(2,3,4,5,6-pentafluorophenyl)methyl]hydroxylamine
  • 57981-02-9
  • C7H5ClF5NO
  • C7H4F5NO
  • C6F5CH2ONH2HCl
  • C7H4F5NOHCl
  • C7H4F5NOClH
  • Biochemicals and Reagents
  • Building Blocks
  • BioChemical
  • Nitrogen Compounds
  • Luminescent Compounds/Detection
  • Organic Building Blocks
  • Derivatization agents
  • Boronic Acid, etc. (GC Derivatizing Reagents)
  • GC Derivatizing Reagents
  • Hydroxylamines (O-Substituted)
  • Hydroxylamines