1,1,1-Trifluoroethyl-PEG3-Propargyl
- Product Name
- 1,1,1-Trifluoroethyl-PEG3-Propargyl
- CAS No.
- 1835759-73-3
- Chemical Name
- 1,1,1-Trifluoroethyl-PEG3-Propargyl
- Synonyms
- 1,1,1-Trifluoroethyl-PEG2-propargyl;1,1,1-Trifluoroethyl-PEG3-Propargyl;1-Propyne, 3-[2-[2-(2,2,2-trifluoroethoxy)ethoxy]ethoxy]-
- CBNumber
- CB83162800
- Molecular Formula
- C9H13F3O3
- Formula Weight
- 226.19
- MOL File
- 1835759-73-3.mol
1,1,1-Trifluoroethyl-PEG3-Propargyl Property
- Boiling point:
- 243.5±35.0 °C(Predicted)
- Density
- 1.152±0.06 g/cm3(Predicted)
- form
- Liquid
- color
- Colorless to light yellow
N-Bromosuccinimide Price
- Product number
- BP-22938
- Product name
- 1,1,1-Trifluoroethyl-PEG3-Propargyl
- Purity
- 98%
- Packaging
- 250mg
- Price
- $480
- Updated
- 2021/12/16
- Product number
- BP-22938
- Product name
- 1,1,1-Trifluoroethyl-PEG3-Propargyl
- Purity
- 98%
- Packaging
- 500mg
- Price
- $750
- Updated
- 2021/12/16
1,1,1-Trifluoroethyl-PEG3-Propargyl Chemical Properties,Usage,Production
Description
1,1,1-Trifluoroethyl-PEG3-Propargyl is a heterobifunctional reagent with an alkyne group and a trifluoroethyl group. The alkyne group reacts with azide compounds or biomolecules in copper catalyzed Click Chemistry to form a stable triazole linkage. The trifluoroethyl group is used to react with lysine and other primary amine groups in proteins, antibody and other molecules and surfaces.
Uses
1,1,1-Trifluoroethyl-PEG2-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. 1,1,1-Trifluoroethyl-PEG2-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
1,1,1-Trifluoroethyl-PEG3-Propargyl Preparation Products And Raw materials
Raw materials
Preparation Products
1,1,1-Trifluoroethyl-PEG3-Propargyl Suppliers
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- United States
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View Lastest Price from 1,1,1-Trifluoroethyl-PEG3-Propargyl manufacturers
- Product
- 1,1,1-Trifluoroethyl-PEG3-propargyl 1835759-73-3
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-27