Azide-PEG3-Sulfone-PEG3-Azide
- Product Name
- Azide-PEG3-Sulfone-PEG3-Azide
- CAS No.
- 2055024-45-6
- Chemical Name
- Azide-PEG3-Sulfone-PEG3-Azide
- Synonyms
- N3-PEG3-Sulfone-PEG3-N3;Azide-PEG3-Sulfone-PEG3-Azide;3,6,9,15,18,21-Hexaoxa-12-thiatricosane, 1,23-diazido-, 12,12-dioxide
- CBNumber
- CB83162855
- Molecular Formula
- C16H32N6O8S
- Formula Weight
- 468.52568
- MOL File
- 2055024-45-6.mol
N-Bromosuccinimide Price
- Product number
- BP-23228
- Product name
- Azide-PEG3-Sulfone-PEG3-azide
- Purity
- 98%
- Packaging
- 100mg
- Price
- $320
- Updated
- 2021/12/16
- Product number
- BP-23228
- Product name
- Azide-PEG3-Sulfone-PEG3-azide
- Purity
- 98%
- Packaging
- 250mg
- Price
- $540
- Updated
- 2021/12/16
- Product number
- BP-23228
- Product name
- Azide-PEG3-Sulfone-PEG3-azide
- Purity
- 98%
- Packaging
- 500mg
- Price
- $750
- Updated
- 2021/12/16
- Product number
- BP-23228
- Product name
- Azide-PEG3-Sulfone-PEG3-azide
- Purity
- 98%
- Packaging
- 1g
- Price
- $1400
- Updated
- 2021/12/16
Azide-PEG3-Sulfone-PEG3-Azide Chemical Properties,Usage,Production
Description
Azide-PEG3-Sulfone-PEG3-azide is a PEG linker containing two azide groups. The azide group enables Click Chemistry with groups such as alkynes, DBCO and BCN. The hydrophilic PEG spacer increases solubility in aqueous media.
Uses
Azide-PEG3-Sulfone-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azide-PEG3-Sulfone-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Azide-PEG3-Sulfone-PEG3-Azide Preparation Products And Raw materials
Raw materials
Preparation Products
Azide-PEG3-Sulfone-PEG3-Azide Suppliers
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View Lastest Price from Azide-PEG3-Sulfone-PEG3-Azide manufacturers
- Product
- Azide-PEG3-Sulfone-PEG3-azide 2055024-45-6
- Price
- US $0.00/mg
- Min. Order
- 500mg
- Purity
- >95.00%
- Supply Ability
- 500mg
- Release date
- 2024-03-28