ChemicalBook > CAS DataBase List > 3-Chloro-2-fluorobenzoic acid
3-Chloro-2-fluorobenzoic acid
Uses- Product Name
- 3-Chloro-2-fluorobenzoic acid
- CAS No.
- 161957-55-7
- Chemical Name
- 3-Chloro-2-fluorobenzoic acid
- Synonyms
- CAS:161957-55-7;BUTTPARK 14\01-29;RARECHEM AL BO 1303;3-Chloro-2-Fluorobenzoic;2-FLUORO-3-CHLOROBENZOIC ACID;3-CHLORO-2-FLUOROBENZOIC ACID;3-Chloro-2-fluoroboronic acid;3-Chloro-2-fluorobenzoicacid98%;Benzoic acid, 3-chloro-2-fluoro-;3-Chloro-2-fluorobenzoic Acid >
- CBNumber
- CB8350200
- Molecular Formula
- C7H4ClFO2
- Formula Weight
- 174.56
- MOL File
- 161957-55-7.mol
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3-Chloro-2-fluorobenzoic acid Property
- Melting point:
- 177-180 °C (lit.)
- Boiling point:
- 278.9±20.0 °C(Predicted)
- Density
- 1.477±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- soluble in Methanol
- form
- powder to crystal
- pka
- 2.90±0.10(Predicted)
- color
- White to Light yellow to Light red
- BRN
- 7127637
- InChI
- InChI=1S/C7H4ClFO2/c8-5-3-1-2-4(6(5)9)7(10)11/h1-3H,(H,10,11)
- InChIKey
- FCSSYEWURMTUSM-UHFFFAOYSA-N
- SMILES
- C(O)(=O)C1=CC=CC(Cl)=C1F
- CAS DataBase Reference
- 161957-55-7(CAS DataBase Reference)
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Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 20/21/22-36/37/38
- Safety Statements
- 22-24/25-36-26
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29163990
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 536318
- Product name
- 3-Chloro-2-fluorobenzoic acid
- Purity
- 98%
- Packaging
- 1g
- Price
- $36.1
- Updated
- 2023/06/20
TCI Chemical
- Product number
- C2117
- Product name
- 3-Chloro-2-fluorobenzoic Acid
- Purity
- >97.0%(GC)(T)
- Packaging
- 5g
- Price
- $21
- Updated
- 2025/07/31
TCI Chemical
- Product number
- C2117
- Product name
- 3-Chloro-2-fluorobenzoic Acid
- Purity
- >97.0%(GC)(T)
- Packaging
- 25g
- Price
- $83
- Updated
- 2025/07/31
TRC
- Product number
- C585648
- Product name
- 3-Chloro-2-fluorobenzoic Acid
- Packaging
- 100mg
- Price
- $75
- Updated
- 2021/12/16
Matrix Scientific
- Product number
- 002086
- Product name
- 3-Chloro-2-fluorobenzoic acid
- Purity
- 98%
- Packaging
- 5g
- Price
- $12
- Updated
- 2021/12/16
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3-Chloro-2-fluorobenzoic acid Chemical Properties,Usage,Production
Uses
3-Chloro-2-fluorobenzoic acid is an important fine chemical intermediate that can be used in the synthesis of pharmaceutical products, bioengineering, reactive dyes, polyester compounds, and pesticides.
Chemical Properties
white to light yellow crystal powder
Synthesis Reference(s)
Tetrahedron Letters, 36, p. 881, 1995 DOI: 10.1016/0040-4039(94)02385-O
Synthesis
85070-48-0
161957-55-7
General procedure for the synthesis of 3-chloro-2-fluorobenzoic acid from 3-chloro-2-fluorobenzaldehyde: An acetone (75 mL) solution of 3-chloro-2-fluorobenzaldehyde (3 g, 18.92 mmol) was slowly added to an aqueous (30 mL) solution of sodium chlorite (6.81 g, 75.68 mmol) under cooling conditions in an ice bath. The reaction mixture was stirred at 0°C for 5 minutes. Subsequently, sulfamic acid (5.50 g, 56.76 mmol) was added all at once and stirring was continued for 30 min at the same temperature. The reaction process was monitored by thin layer chromatography (TLC). After completion of the reaction, the mixture was diluted with water (5 mL) and filtered. The filtrate was extracted with ethyl acetate (3 x 50 mL), the organic layers were combined, dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure to give 3-chloro-2-fluorobenzoic acid as a white solid (3.2 g, 97% yield).LC-MS analysis: 172.9 (M-H).
References
[1] Patent: WO2017/72062, 2017, A1. Location in patent: Page/Page column 166
[2] Patent: WO2008/7149, 2008, A2. Location in patent: Page/Page column 28
3-Chloro-2-fluorobenzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-Chloro-2-fluorobenzoic acid manufacturers
Speranza Chemical Co., Ltd.
- Product
- 3-Chloro-2-fluorobenzoic acid 161957-55-7
- Price
- US $230.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 300 Tons/ year
- Release date
- 2019-12-25
Hebei Zhuanglai Chemical Trading Co Ltd
- Product
- 3-Chloro-2-Fluorobenzoic Acid 161957-55-7
- Price
- US $99.00-45.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20ton
- Release date
- 2024-12-18
Shaanxi Dideu Medichem Co. Ltd
- Product
- 3-Chloro-2-fluorobenzoic acid 161957-55-7
- Price
- US $0.00-0.00/KG
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 2000tons
- Release date
- 2019-12-25
161957-55-7, 3-Chloro-2-fluorobenzoic acidRelated Search:
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