Cyclopropane-1-carboximidamide hydrochloride
Uses- Product Name
- Cyclopropane-1-carboximidamide hydrochloride
- CAS No.
- 57297-29-7
- Chemical Name
- Cyclopropane-1-carboximidamide hydrochloride
- Synonyms
- CYCLOPROPANECARBOXIMIDAMIDE HYDROCHLORIDE;Cyclopropanecarboximidamide;CYCLOPROPYLCARBAMIDINE HYDROCHLORIDE;BUTTPARK 43\57-26;CYCLOPROPYL CARBAMIDINE HCL;cyclopropanecarbamidine, HCl;Cyclopropancecarboxamidine HCl;Cyclopropancecarboxamidine HCI;Cyclopropanecarboximidamide, HCl;Cyclopropaneamidine hydrochloride
- CBNumber
- CB8387657
- Molecular Formula
- C4H9ClN2
- Formula Weight
- 120.58
- MOL File
- 57297-29-7.mol
Cyclopropane-1-carboximidamide hydrochloride Property
- Melting point:
- 123 °C
- storage temp.
- Inert atmosphere,Room Temperature
- Water Solubility
- Soluble in water
- form
- powder to crystal
- color
- White to Almost white
- Sensitive
- Hygroscopic
- BRN
- 4507255
- InChI
- InChI=1S/C4H8N2.ClH/c5-4(6)3-1-2-3;/h3H,1-2H2,(H3,5,6);1H
- InChIKey
- JRYOZJIRAVZGMV-UHFFFAOYSA-N
- SMILES
- C1(C(N)=N)CC1.[H]Cl
- CAS DataBase Reference
- 57297-29-7(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36/37/39-37/39
- WGK Germany
- 3
- Hazard Note
- Irritant/Hygroscopic
- HazardClass
- IRRITANT
- HS Code
- 29252900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 735647
- Product name
- Cyclopropaneamidine hydrochloride
- Purity
- 97%
- Packaging
- 5g
- Price
- $26.5
- Updated
- 2025/07/31
- Product number
- C2344
- Product name
- Cyclopropanecarboxamidine Hydrochloride
- Purity
- >98.0%(N)
- Packaging
- 1g
- Price
- $25
- Updated
- 2025/07/31
- Product number
- C2344
- Product name
- Cyclopropanecarboxamidine Hydrochloride
- Purity
- >98.0%(N)
- Packaging
- 5g
- Price
- $51
- Updated
- 2025/07/31
- Product number
- C992053
- Product name
- CyclopropanecarboximidamideHydrochloride
- Packaging
- 1g
- Price
- $90
- Updated
- 2021/12/16
- Product number
- FC12149
- Product name
- Cyclopropancecarboxamidine HCl
- Packaging
- 25g
- Price
- $150
- Updated
- 2021/12/16
Cyclopropane-1-carboximidamide hydrochloride Chemical Properties,Usage,Production
Uses
Cyproteramidine hydrochloride is a non-selective protease inhibitor that can be used to inhibit the activity of a variety of enzymes.
Chemical Properties
white to light yellow crystal powde
Synthesis
5500-21-0
57297-29-7
The general procedure for the synthesis of cyclopropanecarboxamidine hydrochloride from cyclopropanecarbonitrile is as follows: in a 1 L reactor equipped with thermocouples, underground gas feed lines, hydrogen chloride cylinders, cylinder balancing device, and a nitrogen bubbler, the reactor was first flushed with nitrogen. Cyclopropanecarbonitrile (100 g, 1.5 mol), methanol (48 g, 1.5 mol) and toluene (400 mL) were then added. The reaction mixture was maintained at 15 °C under slight positive nitrogen pressure while anhydrous hydrogen chloride (57 g, 1.55 mol) was slowly added under the surface of the reaction mixture over a period of 2 hours. After addition, the reaction mixture was stirred at 23°C for 16 hours. Nitrogen was bubbled through the reaction mixture below the surface to purge the excess hydrogen chloride while the effluent was expelled through a water scrubber, a process that lasted for 2 hours. The mixture was cooled to 5 °C and then a methanol solution of ammonia (240 mL 7M solution, 1.7 mol) was added over 10 min, during which the temperature was kept below 25 °C. After standing for 1 h, the excess methanol was removed by distillation under reduced pressure. The product obtained was filtered and washed with toluene (100 mL) and finally dried by suction to give 170 g (94% yield) of cyclopropanecarboxamidine hydrochloride as a solid. The 1H NMR (DMSO-J6) data of the product were as follows: δ 8.8 (br s, 4H), 1.84 (m, 1H), 1.1 (m, 4H).
References
[1] Patent: WO2006/121648, 2006, A2. Location in patent: Page/Page column 22-23
[2] Patent: WO2011/58478, 2011, A1. Location in patent: Page/Page column 31
[3] Patent: WO2009/81112, 2009, A2. Location in patent: Page/Page column 113-114
[4] Patent: WO2010/92339, 2010, A1. Location in patent: Page/Page column 83
[5] Patent: US2003/139415, 2003, A1
Cyclopropane-1-carboximidamide hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Cyclopropane-1-carboximidamide hydrochloride Suppliers
- Tel
- 320-37350700
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- +32 (0)37350701
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View Lastest Price from Cyclopropane-1-carboximidamide hydrochloride manufacturers
- Product
- Cyclopropane-1-carboximidamide HCl 57297-29-7
- Price
- US $2.20-8.80/kg
- Min. Order
- 1kg
- Purity
- 99%min
- Supply Ability
- 100kg
- Release date
- 2025-09-08
- Product
- Cyclopropane-1-carboximidamide hydrochloride 57297-29-7
- Price
- US $8.80/KG
- Min. Order
- 1KG
- Purity
- 97%-99%
- Supply Ability
- 100kg
- Release date
- 2019-07-04