Fenofibric acid

Product Name: Fenofibric acid
CAS No.: 42017-89-0
Chemical Name: Fenofibric acid
Synonyms: FENOFIBRATE ACID;lf153;A-1081;FNF Acid;alpha1081;lf178acid;NSC 281318;EP-B/USP RC B;FENOFIBRIC ACID;FeNAfibric acid
CBNumber: CB8400259
Molecular Formula: C17H15ClO4
Formula Weight: 318.75
MOL File: 42017-89-0.mol

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Fenofibric acid Property

Melting point:: 177-179°C
Boiling point:: 486.5±35.0 °C(Predicted)
Density: 1.286±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: Chloroform (Slightly), Methanol (Slightly)
pka: 3.09±0.10(Predicted)
form: powder
color: White to Off-White
BRN: 2058973
InChI: InChI=1S/C17H15ClO4/c1-17(2,16(20)21)22-14-9-5-12(6-10-14)15(19)11-3-7-13(18)8-4-11/h3-10H,1-2H3,(H,20,21)
InChIKey: MQOBSOSZFYZQOK-UHFFFAOYSA-N
SMILES: C(O)(=O)C(OC1=CC=C(C(=O)C2=CC=C(Cl)C=C2)C=C1)(C)C
CAS DataBase Reference: 42017-89-0(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,N
Risk Statements: 36/37/38-50/53-22
Safety Statements: 26-36/37/39-61-60-24/25
RIDADR: UN 3077 9 / PGIII
WGK Germany: 3
RTECS: UA2453000
HazardClass: 9
PackingGroup: III
HS Code: 29189900
Toxicity: LD50 oral in rat: 1242mg/kg

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHR3315
Product name: Fenofibrate Related Compound B
Purity: certified reference material, pharmaceutical secondary standard
Packaging: 50MG
Price: $576
Updated: 2024/03/01

Sigma-Aldrich

Product number: 796565
Product name: Fenofibric acid
Purity: 95%
Packaging: 1g
Price: $29.88
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1269618
Product name: Fenofibrate Related Compound B
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 25mg
Price: $894
Updated: 2024/03/01

TCI Chemical

Product number: F1011
Product name: Fenofibric Acid
Purity: >98.0%(GC)(T)
Packaging: 1g
Price: $30
Updated: 2024/03/01

TCI Chemical

Product number: F1011
Product name: Fenofibric Acid
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $95
Updated: 2024/03/01

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Fenofibric acid Chemical Properties,Usage,Production

Chemical Properties

Fenofibric acid is a white to almost white crystalline powder that is stable under ordinary conditions and has a melting point of 179 – 183°C. Its empirical formula is C17H15ClO4 and molecular weight 318.75. Fenofibric acid is insoluble in water; its solubility increases with pH in buffered media.

Uses

Fenofibric acid, the active metabolite of fenofibrate. Increases Apolipoprotein A-Iediated High-Density Lipoprotein Biogenesis by enhancing transcription of ATP-Binding cassette transporter A1 gene in a liver X receptorependent manner

Uses

Fenofibric acid, the active metabolite of fenofibrate. Increases Apolipoprotein A-I–Mediated High-Density Lipoprotein Biogenesis by enhancing transcription of ATP-Binding cassette transporter A1 gene in a liver X receptor–dependent manner.

Uses

DPP4 inhibitor, antidiabetic

Definition

ChEBI: A monocarboxylic acid that is 2-methylpropanoic acid substituted by a 4-(4-chlorobenzoyl)phenoxy group at position 2. It is a metabolite of the drug fenofibrate.

Metabolism

Fenofibric acid is primarily conjugated with glucuronic acid and then excreted in urine. A small amount of fenofibric acid is reduced at the carbonyl moiety to a benzhydrol metabolite, which is, in turn, conjugated with glucuronic acid and excreted in urine. In vitro and in vivo metabolism data indicate that fenofibric acid does not undergo oxidative metabolism (e.g. cytochrome P450) to a significant extent. The enzymes CYP1A2, CYP2A6, CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6, CYP2E1, and CYP3A4 do not play a role in the metabolism of fenofibric acid.

Fenofibric acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Fenofibric acid manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: Fenofibric Acid 42017-89-0
Price: US $180.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-06-05

Hebei Mujin Biotechnology Co.,Ltd

Product: Fenofibrate Acid 42017-89-0
Price: US $100.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 5000kg/week
Release date: 2021-06-09

HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD

Product: Fenofibric acid 42017-89-0
Price: US $99.00-66.00/kg
Min. Order: 0.00100000kg
Purity: 99%
Supply Ability: 5000
Release date: 2024-08-12

42017-89-0, Fenofibric acidRelated Search:

(4-Chlorophenyl)[4-(1-Methylethoxy)phenyl]Methanone (Fenofibrate IMpurity) FENOFIBRATE RELATED COMPOUND C (25 MG) (1-METHYLETHYL 2-[[2-[4-(4-CHLOROBENZOYL)PHENOXY]-2-METHYLPROPANOYL]OXY]-2-METHYLPROPANOATE) Ethyl 2-(Chlorosulfonyl)acetate Dimethyldimethoxysilane Methyltriethoxysilane Methyltrimethoxysilane Stearic acid Folic acid Citric acid Ethoxymethylenemalononitrile Fenofibrate 2,2-Bis(hydroxymethyl)propionic acid 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropionic acid methyl ester Unii-4bmh7izt98 4-Chloro-4'-hydroxybenzophenone 3-[4-(4-Chlorobenzoyl)phenoxy]-2-butanone (Fenofibrate IMpurity) Diethyl squarate Squaric acid

2-[4-(4-CHLOROBENZOYL)PHENOXY]-2-METHYLPROPANOIC ACID

LABOTEST-BB LT00239222

FENOFIBRIC ACID

SALOR-INT L498335-1EA

2-[4-(4-CHLORO-BENZOYL)-PHENOXY]-2-METHYL-PROPIONIC ACID (FENOFIBRIC ACID)

2-[4-(4-CHLOROBENBONYZOYL)PHENOXY)-2-METHYLPROPIONIC ACID

2-[4'-(p-Chlorobenzoyl)phenoxy]-2-methylpropionic acid

FENOFIBRATE ACID

A-1081

Fenofibrate Related Compound B (25 mg) (2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanoic acid)

Choline Fenofibrate Impurity B

Fenofibrate Impurity 2(Fenofibrate EP Impurity B)

Fenofibrate impurity B (EP)

alpha1081

2-(4-(4-chlorobenzoyl)phenoxy)-2-methyl-propanoicaci

2-[4-[(4-chlorophenyl)-oxomethyl]phenoxy]-2-methylpropanoate

FeNAfibric acid

Fenofibrate EP IMpurity B

2-(4-(4-Chlorobenzoyl)phenoxy)-2-Methylpropanoic acid, 95+%

FNF Acid

NSC 281318

Fenofibric acid, >=99%

2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropionic acid 95%

lf153

lf178acid

procetofenicacid

2-[4-(4-CHLORO-BENZOYL)-PHENOXY]-2-METHYL-PROPIONIC ACID

2-[4-(4-CHLOROBENZOYL) PHENOXY]-2'-METHYL PROPANOIC ACID

Fenofibrate Impurity Ⅱ:Fenofibric acid(2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropionic acid)

FenofibricAcid&gt

Fenofibrate impurity B CRS

Fenofibrate EP Impurity B (Fenofibric Acid)

Propanoic acid, 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-

Fenofibrate USP Related Compound B

Fenofibrate EP Impurity B/ Fenofibrate Related Compound B (Fenofibric Acid)

Fenofibrate impurity B (F0048010)

Fenofibric acid D4

Fenofibric AcidQ: What is Fenofibric Acid Q: What is the CAS Number of Fenofibric Acid Q: What is the storage condition of Fenofibric Acid Q: What are the applications of Fenofibric Acid

Fenofibrate Related Compound B (2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanoic acid) (1269618)

Choline Fenofibrate EP Impurity B

Fenofibric acid,2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropionic acid

EP-B/USP RC B

Fenofibric acid 100 μg/ml Acetone

Fenofibrate Related Compound II（2-[4-（4-chlorobenzoyl)phenoxy]-2-methylpropanoic acid

2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropanoic Acid (Fenofibric Acid)

Fenofibric acid, 10 mM in DMSO

42017-89-0

C17H14ClO4

C20H21CL04

JANUVIA

Various Metabolites and Impurities

Intermediates & Fine Chemicals

Metabolites & Impurities

Pharmaceuticals

pharmacetical

Aromatics