4-Chloro-4'-hydroxybenzophenone
- Product Name
- 4-Chloro-4'-hydroxybenzophenone
- CAS No.
- 42019-78-3
- Chemical Name
- 4-Chloro-4'-hydroxybenzophenone
- Synonyms
- 4-CHLORO-4-HYDROXYBENZOPHENONE;NSC4056;NSC 4056;NSC-4056;4-Chloro-4'-;4-Chloro-4'EP-A /USP RC A;4-Chloro-4'-hydroxyb;-hydroxybenzophenone;LABOTEST-BB LT00248477
- CBNumber
- CB8435031
- Molecular Formula
- C13H9ClO2
- Formula Weight
- 232.66
- MOL File
- 42019-78-3.mol
4-Chloro-4'-hydroxybenzophenone Property
- Melting point:
- 177-181 °C
- Boiling point:
- 257 °C (13 mmHg)
- Density
- 1.2082 (rough estimate)
- refractive index
- 1.5434 (estimate)
- Flash point:
- 100 °C
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly, Sonicated)
- pka
- 7.68±0.15(Predicted)
- color
- Pale Beige to Light Brown
- BRN
- 2049956
- CAS DataBase Reference
- 42019-78-3(CAS DataBase Reference)
- NIST Chemistry Reference
- Methanone, (4-chlorophenyl)(4-hydroxyphenyl)-(42019-78-3)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-20/21/22
- Safety Statements
- 24/25-37/39-26-36
- Hazard Note
- Irritant
- HS Code
- 29144000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- PHR2864
- Product name
- Fenofibrate Related Compound A
- Purity
- Pharmaceutical Secondary Standard; Certified Reference Material
- Packaging
- 50MG
- Price
- $718
- Updated
- 2024/03/01
- Product number
- F0048005
- Product name
- Fenofibrate impurity A
- Purity
- European Pharmacopoeia (EP) Reference Standard
- Packaging
- f0048005
- Price
- $153
- Updated
- 2024/03/01
- Product number
- 1269607
- Product name
- Fenofibrate Related Compound A
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 25mg
- Price
- $894
- Updated
- 2024/03/01
- Product number
- C1155
- Product name
- 4-Chloro-4'-hydroxybenzophenone
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $75
- Updated
- 2024/03/01
- Product number
- C1155
- Product name
- 4-Chloro-4'-hydroxybenzophenone
- Purity
- >98.0%(GC)
- Packaging
- 500g
- Price
- $576
- Updated
- 2024/03/01
4-Chloro-4'-hydroxybenzophenone Chemical Properties,Usage,Production
Chemical Properties
light grey to beige-brown powder
Uses
4-Chloro-4’-hydroxybenzophenone (Fenofibrate EP Impurity A; Fenofibrate USP Related Compound A) the impurity of Fenofibric acid (42017-89-0), the active metabolite of fenofibrate which increases Apolipoprotein A-I–Mediated High-Density Lipoprotein Biogenesis by enhancing transcription of ATP-Binding cassette transporter A1 gene in a liver X receptor–dependent manner.
Preparation
Preparation by Fries rearrangement of phenyl p-chloro-benzoate,
? in the presence of aluminium chloride, without solvent, at 160° for 5 min, between 120° and 160° (good yield) or at 130° for 1 h, then at 160° for 1 h (10%) or in refluxing chlorobenzene for 10 h (52%);
? in the presence of trifluoromethanesulfonic acid at 45–55° (94%).
4-Chloro-4'-hydroxybenzophenone Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-Chloro-4'-hydroxybenzophenone manufacturers
- Product
- 4-p-Chlorobenzoylphenol 42019-78-3
- Price
- US $30.00/kg
- Min. Order
- 1kg
- Purity
- 99.7%
- Supply Ability
- 200000kg
- Release date
- 2024-04-22
- Product
- 4-Chloro-4′-Hydroxybenzophenone 42019-78-3
- Price
- US $15.00-10.00/g
- Min. Order
- 1g
- Purity
- 99.50%
- Supply Ability
- 10kg
- Release date
- 2023-06-25
- Product
- 4-Chloro-4'-hydroxybenzophenone 42019-78-3
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 30tons/month
- Release date
- 2023-02-25