2-FLUORO-4-HYDROXYPYRIDINE
- Product Name
- 2-FLUORO-4-HYDROXYPYRIDINE
- CAS No.
- 22282-69-5
- Chemical Name
- 2-FLUORO-4-HYDROXYPYRIDINE
- Synonyms
- 2-Fluoropyridin-4-ol;2-fluoro-4-Pyridinol;4-Pyridinol, 2-fluoro-;2-fluoro-1H-pyridin-4-one;2-FLUORO-4-HYDROXYPYRIDINE;2-Fluoro-4-hydroxypyridine97%;2-FLUORO-4-HYDROXYPYRIDINE 97%;2-fluoropyridin-4-ol - [F22448];2-FLUORO-4-HYDROXYPYRIDINE ISO 9001:2015 REACH
- CBNumber
- CB8447982
- Molecular Formula
- C5H4FNO
- Formula Weight
- 113.09
- MOL File
- 22282-69-5.mol
2-FLUORO-4-HYDROXYPYRIDINE Property
- Melting point:
- 146-149℃
- Boiling point:
- 377.4±22.0 °C(Predicted)
- Density
- 1.325±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 8.05±0.10(Predicted)
- Appearance
- White to light brown Solid
- InChI
- InChI=1S/C5H4FNO/c6-5-3-4(8)1-2-7-5/h1-3H,(H,7,8)
- InChIKey
- BRLSDLHMGRDAPF-UHFFFAOYSA-N
- SMILES
- C1(F)=NC=CC(O)=C1
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- F600078
- Product name
- 2-Fluoropyridin-4-ol
- Packaging
- 250mg
- Price
- $125
- Updated
- 2021/12/16
- Product number
- F13527
- Product name
- 2-Fluoro-4-hydroxypyridine
- Purity
- >98%
- Packaging
- 1g
- Price
- $100
- Updated
- 2021/12/16
- Product number
- PC01475
- Product name
- 2-Fluoro-4-hydroxypyridine
- Purity
- 95%
- Packaging
- 1g
- Price
- $254
- Updated
- 2021/12/16
- Product number
- 4H01-7-X4
- Product name
- 2-Fluoro-4-hydroxypyridine
- Purity
- 95%
- Packaging
- 1g
- Price
- $280
- Updated
- 2021/12/16
- Product number
- F13527
- Product name
- 2-Fluoro-4-hydroxypyridine
- Purity
- >98%
- Packaging
- 5g
- Price
- $300
- Updated
- 2021/12/16
2-FLUORO-4-HYDROXYPYRIDINE Chemical Properties,Usage,Production
Uses
2-Fluoropyridin-4-ol is a fluoronated pyridine that is used in the synthesis of herbicides and horticultural fungicides.
Synthesis
401815-98-3
22282-69-5
The general procedure for the synthesis of 2-fluoropyridin-4-ol from 2-fluoro-4-pyridinylboronic acid was as follows: trifluoromethylhydrazine (0.05 mmol), 2-fluoropyridin-4-boronic acid (0.5 mmol), potassium tert-butoxide (1.0 mmol) and poly(ethylene glycol)-400 (2.0 g) were added to a 25 mL reaction flask. The mixture was stirred at 100°C until the reaction was complete (monitored by TLC). Upon completion of the reaction, the reaction mixture was cooled to room temperature and the solvent was subsequently removed by evaporation under reduced pressure. Finally, the crude product was purified by column chromatography to afford the target compound 2-fluoropyridin-4-ol in 99% yield.
References
[1] Patent: CN103936538, 2017, B. Location in patent: Paragraph 0073; 0077; 0078
2-FLUORO-4-HYDROXYPYRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-FLUORO-4-HYDROXYPYRIDINE manufacturers
- Product
- 2-FLUORO-4-HYDROXYPYRIDINE 22282-69-5
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.0% min
- Supply Ability
- 100 tons min
- Release date
- 2021-05-26