ChemicalBook > CAS DataBase List > 2-FLUORO-4-HYDROXYPYRIDINE

2-FLUORO-4-HYDROXYPYRIDINE

Product Name: 2-FLUORO-4-HYDROXYPYRIDINE
CAS No.: 22282-69-5
Chemical Name: 2-FLUORO-4-HYDROXYPYRIDINE
Synonyms: 2-Fluoropyridin-4-ol;2-fluoro-4-Pyridinol;4-Pyridinol, 2-fluoro-;2-fluoro-1H-pyridin-4-one;2-FLUORO-4-HYDROXYPYRIDINE;2-Fluoro-4-hydroxypyridine97%;2-FLUORO-4-HYDROXYPYRIDINE 97%;2-fluoropyridin-4-ol - [F22448];2-FLUORO-4-HYDROXYPYRIDINE ISO 9001：2015 REACH
CBNumber: CB8447982
Molecular Formula: C5H4FNO
Formula Weight: 113.09
MOL File: 22282-69-5.mol

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2-FLUORO-4-HYDROXYPYRIDINE Property

Melting point:: 146-149℃
Boiling point:: 377.4±22.0 °C(Predicted)
Density: 1.325±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: 8.05±0.10(Predicted)
Appearance: White to light brown Solid
InChI: InChI=1S/C5H4FNO/c6-5-3-4(8)1-2-7-5/h1-3H,(H,7,8)
InChIKey: BRLSDLHMGRDAPF-UHFFFAOYSA-N
SMILES: C1(F)=NC=CC(O)=C1

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Safety

HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: F600078
Product name: 2-Fluoropyridin-4-ol
Packaging: 250mg
Price: $125
Updated: 2021/12/16

Matrix Scientific

Product number: 073432
Product name: 2-Fluoropyridin-4-ol
Purity: 95+%
Packaging: 1g
Price: $700
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0011641
Product name: 2-FLUORO-4-HYDROXYPYRIDINE
Purity: 95.00%
Packaging: 250MG
Price: $933.24
Updated: 2021/12/16

Frontier Specialty Chemicals

Product number: F13527
Product name: 2-Fluoro-4-hydroxypyridine
Purity: >98%
Packaging: 1g
Price: $100
Updated: 2021/12/16

Apolloscientific

Product number: PC01475
Product name: 2-Fluoro-4-hydroxypyridine
Purity: 95%
Packaging: 1g
Price: $254
Updated: 2021/12/16

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2-FLUORO-4-HYDROXYPYRIDINE Chemical Properties,Usage,Production

Uses

2-Fluoropyridin-4-ol is a fluoronated pyridine that is used in the synthesis of herbicides and horticultural fungicides.

Synthesis

401815-98-3

22282-69-5

The general procedure for the synthesis of 2-fluoropyridin-4-ol from 2-fluoro-4-pyridinylboronic acid was as follows: trifluoromethylhydrazine (0.05 mmol), 2-fluoropyridin-4-boronic acid (0.5 mmol), potassium tert-butoxide (1.0 mmol) and poly(ethylene glycol)-400 (2.0 g) were added to a 25 mL reaction flask. The mixture was stirred at 100°C until the reaction was complete (monitored by TLC). Upon completion of the reaction, the reaction mixture was cooled to room temperature and the solvent was subsequently removed by evaporation under reduced pressure. Finally, the crude product was purified by column chromatography to afford the target compound 2-fluoropyridin-4-ol in 99% yield.

References

[1] Patent: CN103936538, 2017, B. Location in patent: Paragraph 0073; 0077; 0078

2-FLUORO-4-HYDROXYPYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-FLUORO-4-HYDROXYPYRIDINE manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 2-FLUORO-4-HYDROXYPYRIDINE 22282-69-5
Price: US $1.10/g
Min. Order: 1g
Purity: 99.0% min
Supply Ability: 100 tons min
Release date: 2021-05-26

22282-69-5, 2-FLUORO-4-HYDROXYPYRIDINERelated Search:

2-FLUORO-4-HYDROXYPYRIDINE 2-CHLORO-3-FLUORO-5-HYDROXYPYRIDINE 2-CHLORO-5-FLUORO-3-HYDROXYPYRIDINE 3-CHLORO-2-FLUORO-5-HYDROXYPYRIDINE 4-Ethoxy-2-Fluoropyridine 3-BROMO-5-FLUORO-2-HYDROXYPYRIDINE,2-BROMO-5-FLUORO-2-HYDROXYPYRIDINE 3-FLUORO-4-HYDROXYPYRIDINE 97%,3-Fluoro-4-hydroxypyridine97%,3-FLUORO-4-HYDROXYPYRIDINE 2-HYDROXY-4-FLUOROPYRIDINE 3-FLUORO-5-HYDROXYPYRIDINE,3-Fluoro-5-hydroxypyridine97%,5-Fluoro-3-hydroxypyridine,HCPY3003-Fluoro-5-hydroxypyridine 3-BROMO-2-FLUORO-5-HYDROXYPYRIDINE 2-FLUORO-6-HYDROXYPYRIDINE,2-Fluoro-6-hydroxypyridine97%,2-FLUORO-6-HYDROXYPYRIDINE 97% 6-Bromo-2-fluoro-3-hydroxypyridine 2-Fluoro-3-hydroxypyridine97%,2-FLUORO-3-HYDROXYPYRIDINE,3-FLUORO-2-HYDROXYPYRIDINE 6-FLUORO-3-HYDROXYPYRIDINE,2-Fluoro-5-hydroxypyridine98%,2-FLUORO-5-HYDROXYPYRIDINE 4-BROMO-5-FLUORO-2-HYDROXYPYRIDINE 3-FLUORO-2-HYDROXYPYRIDINE,3-Fluoro-2-hydroxypyridine97%,3-Fluoro-2-hydroxypyridine, 3-fluoro-2-pyridone,3-FLUORO-2-HYDROXYPYRIDINE 97% 5-FLUORO-2-HYDROXYPYRIDINE,3-Fluoro-6-hydroxypyridine 3,5-DICHLORO-2,6-DIFLUORO-4-BENZYLOXYPYRIDINE

2-FLUORO-4-HYDROXYPYRIDINE

2-Fluoro-4-hydroxypyridine97%

2-FLUORO-4-HYDROXYPYRIDINE 97%

2-Fluoropyridin-4-ol

2-fluoro-4-Pyridinol

2-fluoro-1H-pyridin-4-one

2-FLUORO-4-HYDROXYPYRIDINE ISO 9001：2015 REACH

4-Pyridinol, 2-fluoro-

2-fluoropyridin-4-ol - [F22448]

22282-69-5

C5H4FNO

Pyridines