N-TERT-BUTYL-ALPHA-PHENYLNITRONE

ChemicalBook > CAS DataBase List > N-TERT-BUTYL-ALPHA-PHENYLNITRONE

N-TERT-BUTYL-ALPHA-PHENYLNITRONE

Product Name: N-TERT-BUTYL-ALPHA-PHENYLNITRONE
CAS No.: 3376-24-7
Chemical Name: N-TERT-BUTYL-ALPHA-PHENYLNITRONE
Synonyms: PBN;N-tert-Butyl-α-phenylnitrone;N-tert-Butyl-α-phenylnitrone;2-PropanaMine, 2-Methyl-N-(phenylMethylene)-, N-oxide;Butylphenylnitrone;Phenyl N-t-butylnitrone;PHENYL-TERT-BUTYLNITRONE;N-T-BUTYL-A-PHENYLNITRONE;PHENYL N-TERT-BUTYLNITRONE;c-phenyl-n-tert-butylnitrone
CBNumber: CB8469861
Molecular Formula: C11H15NO
Formula Weight: 177.24
MOL File: 3376-24-7.mol

Less

N-TERT-BUTYL-ALPHA-PHENYLNITRONE Property

Melting point:: 73-74 °C(lit.)
Boiling point:: 283℃
Density: 0.990
refractive index: 1.5480 (estimate)
Flash point:: 119℃
storage temp.: Store at <= 20°C.
solubility: DMSO: soluble
form: powder
pka: 1.50±0.53(Predicted)
color: white
Water Solubility: Soluble in DMSO (10 mg/ml), chloroform (50 mg/ml), and water (20 mg/ml).
Merck: 14,7056
BRN: 2044028
CAS DataBase Reference: 3376-24-7(CAS DataBase Reference)
EPA Substance Registry System: 2-Propanamine, 2-methyl-N-(phenylmethylene)-, N-oxide (3376-24-7)

Less

Safety

Safety Statements: 22-24/25
WGK Germany: 3
RTECS: TX1760000
F: 10
TSCA: Yes
HS Code: 2929 90 00

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 80126
Product name: N-tert-Butyl-α-phenylnitrone
Purity: for ESR-spectroscopy
Packaging: 1g
Price: $281
Updated: 2024/03/01

Sigma-Aldrich

Product number: 8.41179
Product name: N-tert-Butyl-α-phenylnitrone
Purity: for synthesis
Packaging: 1g
Price: $132
Updated: 2024/03/01

Sigma-Aldrich

Product number: 203995
Product name: N-tert-Butyl-α-phenylnitrone
Purity: Most commonly-used free radical trap.
Packaging: 500mg
Price: $111
Updated: 2024/03/01

TCI Chemical

Product number: B1701
Product name: N-tert-Butyl-alpha-phenylnitrone
Purity: >98.0%(HPLC)(T)
Packaging: 1g
Price: $68
Updated: 2024/03/01

TCI Chemical

Product number: B1701
Product name: N-tert-Butyl-alpha-phenylnitrone
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $218
Updated: 2024/03/01

Less

N-TERT-BUTYL-ALPHA-PHENYLNITRONE Chemical Properties,Usage,Production

Chemical Properties

white to light beige fine crystalline powder

Uses

N-tert-Butyl-a-phenylnitrone is a commonly-used free radical trap. It contains radical scavenging activity and an ability to inhibit Cox-2 (cyclooxygenase-2). N-tert-Butyl-a-phenylnitrone is an antioxidant that has been shown to act as a protective agent in several experimental models of neurodegenerative disorders. N-tert-Butyl-a-phenylnitrone inhibits lipid peroxidation in rat liver microsomes. It also prevents the induction of inducible nitric oxide synthase (iNOS) by reactive oxygen species.

Uses

N-tert-Butyl-α-phenylnitrone has been used:

as a component of Dneasy Blood&Tissue buffer to preserve the oxidized state of DNA extracted from human non-tumorigenic epithelial breast (MCF10A) cells
as a free radical scavenger of reactive oxygen species (ROS) in microglial (MG) cell lines
to attenuate fibroblast senescence in unstable oral squamous cell carcinomas (GU-OSCC)

Uses

Spin trap reagent for carbon- or oxygen- or nitrogen-centered free radicals.

Synthesis Reference(s)

Tetrahedron, 48, p. 8677, 1992 DOI: 10.1016/S0040-4020(01)89443-6

General Description

Most commonly-used free radical trap. An antioxidant that has been shown to act as a protective agent in several experimental models of neurodegenerative disorders. Inhibits lipid peroxidation in rat liver microsomes. Also prevents the induction of inducible nitric oxide synthase (iNOS) by reactive oxygen species.

Biochem/physiol Actions

Product does not compete with ATP.

Purification Methods

Crystallise PBN from hexane. It is a free radical trap. [cf Janzen Methods Enzymology 105 188 1984, Beilstein 7 IV 519.]

N-TERT-BUTYL-ALPHA-PHENYLNITRONE Preparation Products And Raw materials

Raw materials

ZINC Acetonitrile Ethanol Sodium sulfate Toluene 3-Chloroperoxybenzoic acid Benzaldehyde Diethyl ether Benzene Ethyl acetate Hydrochloric acid Sodium bicarbonate Potassium permanganate Acetic acid tert-Butylamine PETROLEUM ETHER

Preparation Products

2-METHYL-N-(PHENYLMETHYLENE)-2-PROPYLAMINE

Less

N-TERT-BUTYL-ALPHA-PHENYLNITRONE Suppliers

Americas 1 Belgium 1 Canada 1 China 114 Europe 1 Germany 4 India 4 Japan 2 Switzerland 3 United Kingdom 5 United States 22 Global 158

Hubei Jiuchang New Material Technology Co., Ltd

Tel: 13407109540
Email: 15216757546@163.com
Country: China
ProdList: 172
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 021-61259108 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Beijing HwrkChemical Technology Co., Ltd

Tel: 010-89508211 18501085097
Fax: 010-89508210
Email: sales.bj@hwrkchemical.com
Country: China
ProdList: 8418
Advantage: 55

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44689
Advantage: 61

Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
Country: China
ProdList: 9809
Advantage: 59

Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18738
Advantage: 57

Syntechem Co.,Ltd

Tel
Fax: E-Mail Inquiry
Email: info@syntechem.com
Country: China
ProdList: 12984
Advantage: 57

Sichuan Kulinan Technology Co., Ltd

Tel: 400-1166-196 18981987031
Fax: 028-84555506 800101999
Email: cdhxsj@163.com
Country: China
ProdList: 11707
Advantage: 57

Beijing Taiya Jie Technology Development Co., Ltd.

Tel: 021-33690831-8001 13552411790
Fax: 021-33690831
Email: postmaster@tyjchem.cn
Country: China
ProdList: 1541
Advantage: 55

Hangzhou Sage Chemical Co., Ltd.

Tel: +86057186818502 13588463833
Fax: Pls mail us for more information!
Email: info@sagechem.com
Country: China
ProdList: 10266
Advantage: 58

Thermo Fisher Scientific

Tel: 800-810-5118
Fax: +86-10-84193589
Email: cnchemical@thermofisher.com
Country: China
ProdList: 17770
Advantage: 75

Beijing innoChem Science & Technology Co.,Ltd.

Tel: 400-810-7969 010-59572699
Fax: 010-59572688
Email: ningzi.li@inno-chem.com.cn
Country: China
ProdList: 6134
Advantage: 55

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 22514
Advantage: 55

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-400-6206333 18521732826
Fax: 021-50323701
Email: market@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

Guangzhou Isun Pharmaceutical Co., Ltd

Tel: 020-39119399 18927568969
Fax: 020-39119999
Email: isunpharm@qq.com
Country: China
ProdList: 4428
Advantage: 55

TargetMol Chemicals Inc.

Tel: 021-021-33632979 15002134094
Fax: 021-33632979
Email: marketing@targetmol.com
Country: China
ProdList: 7783
Advantage: 58

Shanghai BeiZhuo Biotech Co., Ltd.

Tel: 021-61119791,13386096464
Fax: 021-50190009
Email: bzswkf@foxmail.com
Country: China
ProdList: 3921
Advantage: 50

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 41462
Advantage: 60

Hunan HuaTeng Pharmaceutical Co., Ltd.,

Tel: 400-8592883 15367835770
Fax: 0731-82251112
Email: viola@huatengsci.com
Country: China
ProdList: 5875
Advantage: 58

Suzhou yacoo science co.,Ltd

Tel: 0512-87182056 18013166090
Fax: 0512-87182056
Email: lingling.qi@yacoo.com.cn
Country: China
ProdList: 7295
Advantage: 60

Shanghai YuLue Chemical Co., Ltd.

Tel: 021-60345187 13671753212
Fax: 021-34702061
Email: lzz841106@aliyun.com
Country: China
ProdList: 10276
Advantage: 55

Shanghai Xingui Biotechnology Co., Ltd.

Tel: 17501653715
Email: xingui2022@126.com
Country: China
ProdList: 10021
Advantage: 58

Shanghai Macklin Biochemical Co.,Ltd.

Tel: 15221275939 15221275939
Fax: 021-50706099
Email: shenlinxing@macklin.cn
Country: China
ProdList: 16166
Advantage: 55

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51456
Advantage: 80

Codow Chemical Co.,Ltd.

Tel: 18620099427
Fax: +86-20-62619665
Email: amy@howeipharm.com
Country: China
ProdList: 17687
Advantage: 55

Shanghai Xilong Biochemical Technology Co., Ltd.

Tel: 021-52907766-8042
Fax: 021-52906523
Country: China
ProdList: 9941
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 27313
Advantage: 60

parabiochem

Tel: 025-83453382-8005
Fax: 025-83453382
Email: sale@parabiochem.com
Country: China
ProdList: 9595
Advantage: 55

ShangHai Biochempartner Co.,Ltd

Tel: 177-54423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8011
Advantage: 62

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Anhui kuer Bioengineering Co., Ltd

Tel: 0551-65171243 13856024262
Email: kuer@kuerhuaxue.com
Country: China
ProdList: 2997
Advantage: 55

Shandong Ono Chemical Co., Ltd.

Tel: 0539-6362799 20）
Fax: 0539-6362799（To 20）
Country: China
ProdList: 10007
Advantage: 58

9ding chemical ( Shanghai) Limited

Tel: 021-021-52271985 17721149837
Fax: +86 (21) 52271987
Email: sales@9dingchem.com
Country: China
ProdList: 19800
Advantage: 60

Shanghai BaiShun Biological Technology Co., Ltd

Tel: 021-37581181
Fax: 021-57456066
Email: sales@chem-mall.com
Country: China
ProdList: 10330
Advantage: 58

Aikon International Limited

Tel: 025-58859352 18068836627
Fax: 02557626880
Email: sales01@aikonchem.com
Country: China
ProdList: 15084
Advantage: 58

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400-6387771-6038 18902104717
Email: sales@heowns.com
Country: China
ProdList: 21085
Advantage: 60

3A Chemicals

Tel: 400-668-9898
Fax: 010-51582189
Email: service@3achem.com
Country: China
ProdList: 20557
Advantage: 58

Zhengzhou Acme Chemical Co., Ltd.

Tel: 0371-037163312495,13303845143 13303845143
Fax: QQ3001379618
Email: 3001379618@qq.com
Country: China
ProdList: 9990
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52693
Advantage: 58

Beijing OKA biological technology co., LTD

Tel: 010-010-010-62971590 18548936886
Fax: 010-62340519
Email: jack@oka-vip.com
Country: China
ProdList: 6897
Advantage: 58

Henan Alpha Chemical Co., Ltd.

Tel: 0371-0371-55055611 18137792234
Fax: QQ：3002694073
Email: 3002694073@qq.com
Country: China
ProdList: 10569
Advantage: 58

Shanghai UCHEM Inc.

Tel: +862156762820 +86-13564624040
Email: sales@myuchem.com
Country: China
ProdList: 7514
Advantage: 58

Zhejiang J&C Biological Technology Co.,Limited

Tel: +1-2135480471 +1-2135480471
Email: sales@sarms4muscle.com
Country: China
ProdList: 10473
Advantage: 58

Henan Alfa Chemical Co., Ltd

Tel: +86-18339805032; +8618339805032
Email: alfa4@alfachem.cn
Country: China
ProdList: 13227
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: +86-0551-65418671 +8618949823763
Fax: 0551-65418697
Email: sales@tnjchem.com
Country: China
ProdList: 34553
Advantage: 58

CD Chemical Group Limited

Tel: +8615986615575
Fax: 0086-13651442114
Email: info@codchem.com
Country: China
ProdList: 20342
Advantage: 58

Dayang Chem (Hangzhou) Co.,Ltd.

Tel: 571-88938639 +8617705817739
Fax: +86-571-88938652，+86-571- 88492614
Email: info@dycnchem.com
Country: China
ProdList: 52849
Advantage: 58

Less

View Lastest Price from N-TERT-BUTYL-ALPHA-PHENYLNITRONE manufacturers

Shanghai UCHEM Inc.

Product: N-tert-Butyl-α-phenylnitrone 3376-24-7
Price: US $79.00-519.00/g
Min. Order: 5g
Purity: 0.97
Supply Ability: 25kg
Release date: 2023-12-27

Shaanxi Dideu Medichem Co. Ltd

Product: N-TERT-BUTYL-ALPHA-PHENYLNITRONE 3376-24-7
Price: US $1.00/Kg
Min. Order: 1Kg
Purity: 98%
Supply Ability: 20T
Release date: 2024-07-19

Career Henan Chemical Co

Product: 3376-24-7 3376-24-7
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1kg,5kg,100kg
Release date: 2019-07-04

3376-24-7, N-TERT-BUTYL-ALPHA-PHENYLNITRONERelated Search:

1H-Benzotriazol-1-yloxytris(dimethylamino)phosphonium Hexafluorophosphate 1-Hydroxy-2,2,6,6-tetramethyl-4-oxopiperidine N-TERT-BUTYL-ALPHA-PHENYLNITRONE tert-Butylamine NITRON PTIO CARBOXY-PTIO 2-(4-NITROPHENYL)-4,4,5,5-TETRAMETHYLIMIDAZOLINE-3-OXIDE-1-OXYL N-TERT-BUTYL-D9-PHENYL-D5-NITRONE N-TERT-BUTYL-ALPHA-(2-SULFOPHENYL)NITRO& BENZYLIDENE(2-HYDROXYIMINO-1,1-DIMETHYLETHYL)AMMONIUMOLATE N-(1-CYANO-1-METHYLETHYL)-A-PHENYLNITRONE 5-AMINO-4,4-DIMETHYL-2-PHENYL-4H-IMIDAZOLE-3-OXIDE 2-(4-CARBOXYPHENYL)-4,4,5,5-TETRAMETHYLIMIDAZOLINE-1-OXYL-3-OXIDE, NA N-TERT-BUTYL-ALPHA-(2,4,6-TRIMETHOXY-PHENYL)NITRONE, 99 1H-IMIDAZOL-1-YLOXY, 2-(1,3-BENZODIOXOL-5-YL)-4,5-DIHYDRO-4,4,5,5-TETRAMETHYL-, 3-OXIDE 2-(4-Carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide 3,3,4,4-TETRAMETHYL-2-TRIMETHYLAMMONIOPHENYL-2-IMIDAZOLINE-3-OXIDE-1-YLOXY CHLORIDE

c-phenyl-n-tert-butylnitrone

n-benzylidene-tert-butylamineoxide

n-tert-butyl-2-phenylnitrone

n-tert-butyl-alpha-phenyl-nitron

n-tert-butyl-c-phenylnitrone

(Z)-N-benzylidene-2-Methylpropan-2-aMine oxide

PHENYL N-TERT-BUTYLNITRONE

PBN

N-BENZYLIDENE-TERT-BUTYLAMINE N-OXIDE

N-T-BUTYL-ALPHA-PHENYLNITRONE

N-TERT-BUTYL-ALPHA-PHENYLNITRONE

N-TERT-BUTYL-A-PHENYLNITRONE

N-tert-Butyl-α-phenylnitrone(PBN)

N-tert-Butyl-α-phenylnitrone - CAS 3376-24-7 - Calbiochem

N-Benzylidene-2-methylpropan-2-amine oxide

BENZYLIDENE(TERT-BUTYL)AMMONIUMOLATE

Phenyl N-t-butylnitrone

Butylphenylnitrone

N-benzyliden-tert-butylamine N-ether

N-tert-Butyl-α-phenylnitrone

N-T-BUTYL-A-PHENYLNITRONE

N-TERT-BUTYL-ALPHA-PHENYLNITRONE (PNB)

à-phenyl-n-tert-butylnitrone

n-tert-butyl-à-phenylnitrone

PHENYL-TERT-BUTYLNITRONE

N-tert-Butyl-ɑ-phenylnitrone, 98%

N-tert-B-butyl-alpha-phenylnitrone,98%

2-Methyl-N-(phenylmethylene)-2-propanamine N-oxide

2-Methyl-N-(phenylmethylene)-2-propanamine oxide

N-tert-Butyl-alpha-phenylnitrone,98%

N-tert-Butyl-α-phenylnitrone ,98%

N-tert-Butyl-α-phenylnitrone,N-Benzylidene-tert-butylamine N-oxide, PBN, Phenyl N-t-butylnitrone

2-methyl-n-(phenylmethylene)-2-propanaminn-oxide

2-methyl-n-(phenylmethylene)-s-propanaminen-oxide

2-methyl-n-(phenylmethylene)-s-propanaminn-oxide

2-phenyl-n-tert-butylnitrone

alpha-phenyl-n-tert-butylnitrone

Benzylidene(tert-butyl)azane oxide

benzylidene-tert-butylaminen-oxide

N-tert-Butyl-alpha-phenylnitrone, 98% 5GR

2-PropanaMine, 2-Methyl-N-(phenylMethylene)-, N-oxide

Benzylidene-tert-butylamine oxide

tert-Butyl(benzylidene)amine N-oxide

N-tert-Butyl-alpha-phenylnitrone&gt

N-TERT-BUTYL-A-PHENYLNITRONE FOR SYNTHES

(E)-tert-butyl(oxido)(phenylmethylidene)azanium

N-benzylidene-t-butylamine N-oxide

N-tert-Butyl-α-phenylnitrone, 95%+

N-tert-Butyl-α-phenylnitrone

N-benzylidene-2-methylpropane-2-amine oxide

N-tert-Butyl-α-phenylnitrone(PBN)

n-tert-butyl-n-[(e)-phenylmethylene]amine oxide

3376-24-7

C6H5CHNOCCH33

Biochemicals and Reagents

BioChemical

Cell Signaling Enzymes

Application Index