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Hyaluronidase

Product Name
Hyaluronidase
CAS No.
9001-54-1
Chemical Name
Hyaluronidase
Synonyms
HAase;Aidase;Hyalas;Atidase;Mucinase;Diffusin;Enzodase;Hyaluron;Type I-S;Hyalidase
CBNumber
CB8486088
Molecular Formula
C18H14O7
Formula Weight
342.29956
MOL File
9001-54-1.mol
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Hyaluronidase Property

storage temp. 
−20°C
form 
lyophilized powder
color 
white to slightly brown
Merck 
13,4777
InChI
InChI=1S/C18H14O7/c19-13(11-2-4-15-17(6-11)25-9-23-15)7-12(18(20)21)10-1-3-14-16(5-10)24-8-22-14/h1-6,12H,7-9H2,(H,20,21)
InChIKey
PPEBBOHQEAQKSW-UHFFFAOYSA-N
SMILES
C(O)(=O)C(C1=CC=C2OCOC2=C1)CC(C1=CC=C2OCOC2=C1)=O
EPA Substance Registry System
Hyaluronidase (9001-54-1)
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
3-10
HS Code 
35079090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
H1115000
Product name
Hyaluronidase
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
50 mg
Price
$233
Updated
2025/07/31
Sigma-Aldrich
Product number
H1115000
Product name
Hyaluronidase
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
h1115000
Price
$218
Updated
2024/03/01
American Custom Chemicals Corporation
Product number
ENZ0001491
Product name
Hyaluronidase
Purity
95.00%
Packaging
5MG
Price
$498.81
Updated
2021/12/16
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Hyaluronidase Chemical Properties,Usage,Production

Chemical Properties

Vitaminase is an enzyme extracted from mammalian testes that can hydrolyze glassy mucopolysaccharides, it is a white or slightly yellow powder, soluble in water, insoluble in ethanol, acetone or ether. Odorless. Stability is good, 420C continuous heating for 60 min without loss of vitality, 1000C continuous heating for 5 min can retain 80% of the vitality. It is easy to be inactivated in low concentration of aqueous solution, and can be protected by gelatin or gum arabic to prevent inactivation.Fe2+ and Cu2+ ions have reversible inhibition on the enzyme, while Pb2+, Hg2+, Ni2+ and other ions have no significant effect on the enzyme activity. The inhibitory effect of chondroitin B sulfate (dermatophyte), heparin sulfate, keratin sulfate, sodium heparin, and high concentrations of vitric acid on vitreous acid enzyme was reversed in the presence of sodium chloride (0.15 mol/L) or fisetin sulfate. Vitaminase Injection is a sterile, freeze-dried product of vitaminase plus a suitable excipient as a white or off-white lyophilized mass or powder. The aqueous solution is unstable and needs to be prepared before clinical use.

Uses

Pharmaceutic aid (diffusing agent in s.c. injections).

brand name

Diffusin (Ortho Pharmaceutical); Enzodase (Bristol-Myers Squibb); Hyazyme (Abbott); Vitrase (Biozyme Laboratories Ltd., UK); Wydase (Wyeth-Ayerst);Hylase.

Purification Methods

Hyaluronidase is purified by chromatography on DEAE-cellulose prior to use. [Distler & Jourdain J Biol Chem 248 6772 1973.]

Hyaluronidase Preparation Products And Raw materials

Raw materials

Preparation Products

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Hyaluronidase Suppliers

BIOINDUSTRIA L.I.M. S.P.A.
Tel
--
Fax
--
Email
export@bioindustria.it
Country
Italy
ProdList
12
Advantage
58
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View Lastest Price from Hyaluronidase manufacturers

RongNa Biotechnology Co.,Ltd
Product
Hyaluronidase 9001-54-1
Price
US $10.00/ASSAYS
Min. Order
1ASSAYS
Purity
99%
Supply Ability
1 ton
Release date
2025-08-27
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Hyaluronidase 9001-54-1
Price
US $0.00/G
Min. Order
1G
Purity
98%min
Supply Ability
30kg/month
Release date
2023-02-08
Watson Biotechnology Co.,Ltd
Product
Hyaluronidase 9001-54-1
Price
US $0.00-0.00/G
Min. Order
1G
Purity
805 u/mg
Supply Ability
100G
Release date
2024-08-10

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